OCT News and Research

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Study offers insight into handling the COVID-19 pandemic with biased data

Accurate and near real-time data on the course and evolution of the COVID-19 pandemic have been instrumental in informing public health mitigation strategies and policy worldwide.

22 Oct 2021

TEDDY study adds to a growing body of evidence that type 1 diabetes is not a single disease

New findings from the international The Environmental Determinants of Diabetes in the Young (TEDDY) study add to a growing body of evidence indicating that type 1 diabetes is not a single disease. The presentation and, perhaps, cause of autoimmune diabetes differs among genetically high-risk children, the research suggests.

22 Oct 2021

Researchers identify a potential pathogenic link between IBD and mental comorbidities

In response to gut inflammation, such as that caused by inflammatory bowel disease (IBD), the vascular barrier in the brain choroid plexus closes, locking down access to the brain, according to a new study.

22 Oct 2021

Bacteria defend themselves against viral predators with exchangeable genetic elements

Bacterial viruses, so-called phages, destroy bacteria. Bacteria are constantly exposed to viral attacks. A research team led by Martin Polz, a microbiologist at the University of Vienna, has now studied how bacteria defend themselves against viral predators.

22 Oct 2021

Experts address the limitations of studying individual brains in cognitive neuroscience

In a new paper, scientists suggest that efforts to understand human cognition should expand beyond the study of individual brains. They call on neuroscientists to incorporate evidence from social science disciplines to better understand how people think.

22 Oct 2021

Researchers find a new way to analyze diseased and healthy cells from brain tumor patients

Scientists studying the most common and aggressive type of brain tumor in adults have discovered a new way of analyzing diseased and healthy cells from the same patient.

22 Oct 2021

STI and HIV services in crisis pregnancy centers could cause real harm to public health

Cases of sexually transmitted infections (STIs) and HIV are again on the rise in the U.S., giving new urgency to ongoing efforts to make STI and HIV services more accessible.

21 Oct 2021

Cell-free DNA can help detect measurable residual disease in children with medulloblastoma

Scientists at St. Jude Children's Research Hospital have shown that cell-free DNA from cerebrospinal fluid (CSF) can be used to detect measurable residual disease (MRD) in children treated for the brain tumor medulloblastoma.

21 Oct 2021

New online tool effective in supporting smoke and tobacco free policies on college campuses

A unique study published today in the Oxford University Press journal Nicotine & Tobacco Research looks at the impact of a new online reporting tool in shaping college campus attitudes and behaviors about smoke and tobacco free (STF) policies.

21 Oct 2021

Researchers identify a common gene variant that drives the efficiency and outcome of dialysis

Every day, the human kidneys clean about 1,500 liters of blood by producing approximately 1–2 liters of urine. Thereby, the body gets rid of excess water and toxic waste products of the metabolism or also drugs and maintains the balance of water and minerals in the tissues.

21 Oct 2021

Study: Covid-19 vaccine is over 90% effective at preventing deaths from Delta

Vaccination is over 90 per cent effective at preventing deaths from the Delta variant of Covid-19, according to the first country-level data on mortality.

21 Oct 2021

Innovative method greatly simplifies the complexity of delivering vaccines

Future vaccine delivery may rely on everyday items like BBQ lighters and microneedles, thanks to the ingenuity of a team of Georgia Institute of Technology and Emory University researchers.

21 Oct 2021

Pitt researchers to contribute to building an atlas of cellular senescence

Most cells throughout the body can divide and multiply to replace old cells and repair damaged tissue, but in response to certain stresses, cells can lose their ability to proliferate. These so-called senescent cells accumulate with age and may contribute to cancer and age-related disorders, such as chronic lung disease, cardiovascular disease, frailty and dementia, by pumping out signals that damage neighboring tissues.

21 Oct 2021

New system aims to maximize protection, minimize costs while planning epidemic interventions

A team of researchers has created a software system designed to model epidemics, with the aim of maximizing public-health protections while minimizing economic and social costs.

21 Oct 2021

Researchers employ novel algorithm to identify candidate cancer drugs for pulmonary hypertension

By combining computational and experimental approaches, University of Pittsburgh School of Medicine and Prairie View A&M University researchers identified cancer drugs that show promise for treating pulmonary hypertension, or PH, a rare and incurable lung disease.

21 Oct 2021

Skeletal muscle in individuals with type 2 diabetes has a different circadian rhythm, research shows

Almost all cells regulate their biological processes over a 24-hour period, otherwise called a cell's circadian rhythm. To do so, cells use a biological clock that cycles different genes on and off throughout the day and night. Scientists already know that our metabolic health can suffer when our biological clock breaks down, due to shift work or sleep disorders, for example. However, it's unclear how exactly the biological clock of people with type 2 diabetes differs from healthy people.

21 Oct 2021

Research reveals the mechanisms of cardiac sex disparities at an early stage

Males and females differ in prevalence, treatment responses, and survival rates for a variety of diseases. For cardiac disease, women almost uniformly fare far worse than men. There are likely many reasons for this, and scientists at the University of North Carolina at Chapel Hill and Princeton University seemed to have found one deep inside cells before we're even born.

21 Oct 2021

OCT News and Research

Study offers insight into handling the COVID-19 pandemic with biased data

TEDDY study adds to a growing body of evidence that type 1 diabetes is not a single disease

Researchers identify a potential pathogenic link between IBD and mental comorbidities

Bacteria defend themselves against viral predators with exchangeable genetic elements

Experts address the limitations of studying individual brains in cognitive neuroscience

Researchers find a new way to analyze diseased and healthy cells from brain tumor patients

STI and HIV services in crisis pregnancy centers could cause real harm to public health

Cell-free DNA can help detect measurable residual disease in children with medulloblastoma

New online tool effective in supporting smoke and tobacco free policies on college campuses

Researchers identify a common gene variant that drives the efficiency and outcome of dialysis

Study: Covid-19 vaccine is over 90% effective at preventing deaths from Delta

Innovative method greatly simplifies the complexity of delivering vaccines

Pitt researchers to contribute to building an atlas of cellular senescence

New system aims to maximize protection, minimize costs while planning epidemic interventions

Researchers employ novel algorithm to identify candidate cancer drugs for pulmonary hypertension

Skeletal muscle in individuals with type 2 diabetes has a different circadian rhythm, research shows

Research reveals the mechanisms of cardiac sex disparities at an early stage

Researchers challenge long-held assumption about ML trade-offs in public policy decisions

Interferon treatment coupled with bone marrow transplant reduces risk of leukemia recurrence

First-in-human study of DBS for post-stroke rehabilitation shows encouraging results

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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