Proliferation News and Research

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UA researchers seek to better understand NHE8 protein’s role in GI disorders, colon cancer

About 1.6 million Americans suffer from inflammatory bowel disease (IBD), which encompasses several painful and complex disorders that include Crohn's disease and ulcerative colitis.

27 Jul 2017

UC scientists take different approach to investigating how influenza spreads through the lungs

Influenza is a recurring global health threat that, according to the World Health Organization, is responsible for as many as 500,000 deaths every year, most due to influenza pneumonia, or viral pneumonia.

25 Jul 2017

Low vitamin D may affect recovery of injured corneas

Injury or disease in combination with too little vitamin D can be bad for the window to your eyes. The three-layer, transparent cornea at the front of the eyes focuses the light coming in. But its prominent position also puts it at risk for injury from an errant mascara wand or over-prodding finger or a car accident.

24 Jul 2017

Testing treatments using pig model may help minimize drug failure rates for chronic conditions

Scientists may be able to minimize the failure rate of drugs for diseases linked to high-calorie diets, such as colon cancer and type 2 diabetes, if they test treatments using a pig model, according to an international team of researchers.

21 Jul 2017

Researcher models heart attack in petri dishes to gain insights into cardiac diseases

In petri dishes in her campus laboratory at New Jersey Institute of Technology, Alice Lee is developing colonies of cardiac cells, formed into chambers, that pump and contract like a human heart.

18 Jul 2017

Scientists reveal key role of TLK2 gene in placenta development, embryo viability in mice

The placenta, a transient organ that links the developing embryo to its mother, is responsible for nutrient, waste and gas exchange between the fetus and the mother.

17 Jul 2017

Bacterium S. gallolyticus appears to actively promote development of colorectal cancer

Colorectal cancer is fairly treatable when caught early with regular screenings, but it is still the second-leading cause of cancer-related deaths in American men and the third-leading cause in women.

17 Jul 2017

MGH researchers identify novel mechanism behind resistance to angiogenesis inhibitors

A Massachusetts General Hospital research team has identified a novel mechanism behind resistance to angiogenesis inhibitors - drugs that fight cancer by suppressing the formation of new blood vessels.

14 Jul 2017

Researchers discover potential substitutes for BPA that lack adverse effects

Researchers at Baylor College of Medicine have identified a group of potential substitutes for bisphenol A (BPA) that lack the adverse effects typically associated with BPA.

14 Jul 2017

New partnership to advance novel airway-delivered gene therapy for treating pulmonary hypertension

Mount Sinai has partnered with Theragene Pharmaceuticals, Inc. to advance a novel airway-delivered gene therapy for treating pulmonary hypertension (PH), a form of high blood pressure in blood vessels in the lungs that is linked to heart failure.

13 Jul 2017

ERYTECH partners with Queen’s University to advance its product candidate for treating arginase-1 deficiency

ERYTECH Pharma, a French clinical-stage biopharmaceutical company developing innovative therapies for rare forms of cancer and orphan diseases, today announced that it has entered into a research collaboration with Queen's University in Canada to advance the preclinical development of ERYTECH's eryminase program specifically for the treatment of arginase-1 deficiency, a rare and severe metabolic disorder related to arginine metabolism.

12 Jul 2017

Collagen found to regulate epidermal proliferation in juvenile and aged skin

Type XVII collagen (COL17) is found to regulate the proliferation of epidermal cells and therefore the thickness of juvenile and aged skin, suggesting COL17 can potentially be used for future anti-aging strategies.

11 Jul 2017

New technology could help patients requiring stem cell therapies for Parkinson's, stroke, other diseases

A groundbreaking advancement in materials from Northwestern University could potentially help patients requiring stem cell therapies for spinal cord injuries, stroke, Parkinson's disease, Alzheimer's disease, arthritic joints or any other condition requiring tissue regeneration, according to a new study.

10 Jul 2017

Prolonged use of cancer inhibitors can lead to severe cardiovascular problems

Plk1 inhibitors have recently been acknowledged as an "Innovative Therapy for leukaemia" by the US Food and Drug Administration.

10 Jul 2017

New marker may help diagnose late-stage lung cancer

Investigators have found a new marker that might be used for diagnosing a common form of lung cancer, especially at late stages.

10 Jul 2017

High-throughput screening technique reveals new brain cancer drug targets

Researchers from Case Western Reserve University School of Medicine and The Cleveland Clinic designed a way to screen brain tumor cells and identify potential drug targets missed by other methods.

5 Jul 2017

Novel micro-cubes can efficiently deliver hydrophobic anti-tumor drug to cancer cells

Many potent anti-cancer drugs have major drawbacks -- they fail to mix with water, which means they will have a limited solubility in blood, and they lack selectivity to cancer cells.

29 Jun 2017

Discovery of T cell exhaustion offers new pathway to more powerful immunotherapies

St. Jude Children's Research Hospital immunologists have discovered how immune cells called T cells become "exhausted" -- unable to do their jobs of attacking invaders such as cancer cells or viruses.

28 Jun 2017

Mouse brain models reveal insights into genetics of autism

While the definitive causes remain unclear, several genetic and environmental factors increase the likelihood of autism spectrum disorder, or ASD, a group of conditions covering a "spectrum" of symptoms, skills and levels of disability.

28 Jun 2017

Researchers question use of fungicides on imported flowers, bulbs that induce antifungal drug resistance

Researchers in Manchester are questioning the legal use of certain fungicides used on imported flowers and bulbs following evidence that they induce resistance to the drugs used to treat patients with Aspergillus fumigatus, a virulent of fungal disease.

From The University of Manchester 27 Jun 2017

Proliferation News and Research

UA researchers seek to better understand NHE8 protein’s role in GI disorders, colon cancer

UC scientists take different approach to investigating how influenza spreads through the lungs

Low vitamin D may affect recovery of injured corneas

Testing treatments using pig model may help minimize drug failure rates for chronic conditions

Researcher models heart attack in petri dishes to gain insights into cardiac diseases

Scientists reveal key role of TLK2 gene in placenta development, embryo viability in mice

Bacterium S. gallolyticus appears to actively promote development of colorectal cancer

MGH researchers identify novel mechanism behind resistance to angiogenesis inhibitors

Researchers discover potential substitutes for BPA that lack adverse effects

New partnership to advance novel airway-delivered gene therapy for treating pulmonary hypertension

ERYTECH partners with Queen’s University to advance its product candidate for treating arginase-1 deficiency

Collagen found to regulate epidermal proliferation in juvenile and aged skin

New technology could help patients requiring stem cell therapies for Parkinson's, stroke, other diseases

Prolonged use of cancer inhibitors can lead to severe cardiovascular problems

New marker may help diagnose late-stage lung cancer

High-throughput screening technique reveals new brain cancer drug targets

Novel micro-cubes can efficiently deliver hydrophobic anti-tumor drug to cancer cells

Discovery of T cell exhaustion offers new pathway to more powerful immunotherapies

Mouse brain models reveal insights into genetics of autism

Researchers question use of fungicides on imported flowers, bulbs that induce antifungal drug resistance

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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