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IUPUI scientists develop new synthetic method to shorten drug discovery and development process

Synthesizing useful new compounds is what pharmaceutical discovery and development is all about. Researchers at the School of Science at Indiana University-Purdue University Indianapolis have devised a method to substantially speed up the process.

1 Dec 2016

Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

Multiple sclerosis is an autoimmune disease in which the body's immune system attacks the patient's own cells.

1 Dec 2016

OHSU scientists identify potential target for preventing and treating Alzheimer's disease

A new scientific discovery may provide a future avenue for treatment and prevention of Alzheimer's disease.

1 Dec 2016

Type 2 diabetes linked to long list of complications that can affect health and quality of life

T2D Lifestyle, a national survey by Health Union of more than 400 individuals living with type 2 diabetes (T2D), reveals that patients not only struggle with commonly understood complications, but also numerous lesser known ones that people do not associate with diabetes.

1 Dec 2016

Newborns with low levels of vitamin D may more likely develop multiple sclerosis in later life

Babies born with low levels of vitamin D may be more likely to develop multiple sclerosis (MS) later in life than babies with higher levels of vitamin D, according to a study published in the November 30, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.

30 Nov 2016

Researchers use microbubbles and ultrasound to transport drugs across blood–brain barrier

The impassable blood-brain barrier prevents microorganisms from entering our brain, however it also blocks medicines that could help treat Parkinson's, Alzheimer's and other neurodegenerative diseases.

30 Nov 2016

TUM scientists uncover molecular mechanisms of inhibitors that can selectively thwart immunoproteasome

The immunoproteasome dismantles proteins and the resulting fragments are displayed on the surface of cells. This helps the immune system to recognize abnormal cells. However, in chronic inflammations and autoimmune diseases this “information channel” is overactive.

29 Nov 2016

Sheffield haematologist wins prestigious Anthony Nolan Supporter Award

Professor John Snowden, Consultant Haematologist at Sheffield Teaching Hospitals NHS Foundation Trust, was presented with a national award by the blood cancer charity Anthony Nolan.

25 Nov 2016

Research identifies presence of neuron-producing stem cells in meninges

A multidisciplinary research, conceived by Dr. Francesco Bifari, Department of Medical Biotechnology and Translational Medicine, University of Milan, Italy and Dr. Ilaria Decimo University of Verona, Italy, found that meninges - the protective membranes that enclose the brain - contain of a pool of neural stem cells.

24 Nov 2016

Researchers uncover neural progenitors in protective membranes covering the brain

In a cross-domain study directed by professor Peter Carmeliet (VIB - KU Leuven), researchers discovered unexpected cells in the protective membranes that enclose the brain, the so called meninges.

24 Nov 2016

Sutter Health awarded $1.2 million by California Initiative to advance precision of care for multiple sclerosis

The not-for-profit Sutter Health network was awarded $1.2 million by the California Initiative to Advance Precision Medicine to support patients with multiple sclerosis—and help improve how we target and treat health matters across the entire state.

23 Nov 2016

Palliative care improves patients' survival and quality of life, study shows

People living with serious illness who receive palliative care have better quality of life and fewer symptoms than those who don't receive palliative care, according to a new study by researchers at the University of Pittsburgh School of Medicine.

22 Nov 2016

Researchers call sun avoidance as emerging health problem in the U.S.

A landmark study published Friday in the Journal Dermato-Endocrinology has world-renowned researchers calling insufficient sun exposure an emerging health problem in the United States.

21 Nov 2016

Researchers discover protein complex that enables 'quality control' of immune T cells

The research into T cell development within an organ called the thymus revealed for the first time that a protein complex called LUBAC enables 'quality control' of the cells before they are released into the bloodstream.

18 Nov 2016

Scientists identify naturally occurring molecule that plays protective role in ALS

Researchers at the Virginia Tech Carilion Research Institute have identified a naturally occurring molecule that has the potential for preserving sites of communication between nerves and muscles in amyotrophic lateral sclerosis (ALS) and over the course of aging -- as well as a molecule that interferes with this helpful process.

18 Nov 2016

Psoriatic arthritis patients experience multiple symptoms that can make diagnosis difficult, survey reveals

Psoriatic arthritis (PsA) is an inflammatory condition closely related to and most often co-occurring with psoriasis.

16 Nov 2016

Children born to mothers with rheumatoid arthritis may have increased risk of developing epilepsy

A new study shows a link between mothers with rheumatoid arthritis and children with epilepsy.

16 Nov 2016

Statins can help prevent first time heart attacks, strokes in adults with cardiovascular risk factors

Cholesterol-lowering drugs help prevent heart attacks and strokes in adults with cardiovascular risk factors such as high cholesterol, high blood pressure, diabetes and smoking, but have not yet had a heart attack or stroke, according to a large-scale analysis of clinical trial data led by the OHSU Pacific Northwest Evidence-Based Practice Center.

14 Nov 2016

Researchers identify mechanism of how circadian clocks in neurons encode daily rhythms of excitability

Molecular clocks in cells throughout the body control many physiologic changes in a 24-hour day/night circadian rhythm -- among them the timing of sleep and wakefulness.

14 Nov 2016

Drug approved for other purposes can promote recovery from acute nerve damage, study shows

Researchers at the University of Rochester Medical Center believe they have identified a new means of enhancing the body's ability to repair its own cells, which they hope will lead to better diagnosis and treatment of traumatic nerve injuries, like those sustained in car accidents, sports injuries, or in combat.

14 Nov 2016

Sclerosis News and Research

IUPUI scientists develop new synthetic method to shorten drug discovery and development process

Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

OHSU scientists identify potential target for preventing and treating Alzheimer's disease

Type 2 diabetes linked to long list of complications that can affect health and quality of life

Newborns with low levels of vitamin D may more likely develop multiple sclerosis in later life

Researchers use microbubbles and ultrasound to transport drugs across blood–brain barrier

TUM scientists uncover molecular mechanisms of inhibitors that can selectively thwart immunoproteasome

Sheffield haematologist wins prestigious Anthony Nolan Supporter Award

Research identifies presence of neuron-producing stem cells in meninges

Researchers uncover neural progenitors in protective membranes covering the brain

Sutter Health awarded $1.2 million by California Initiative to advance precision of care for multiple sclerosis

Palliative care improves patients' survival and quality of life, study shows

Researchers call sun avoidance as emerging health problem in the U.S.

Researchers discover protein complex that enables 'quality control' of immune T cells

Scientists identify naturally occurring molecule that plays protective role in ALS

Psoriatic arthritis patients experience multiple symptoms that can make diagnosis difficult, survey reveals

Children born to mothers with rheumatoid arthritis may have increased risk of developing epilepsy

Statins can help prevent first time heart attacks, strokes in adults with cardiovascular risk factors

Researchers identify mechanism of how circadian clocks in neurons encode daily rhythms of excitability

Drug approved for other purposes can promote recovery from acute nerve damage, study shows

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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