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Research highlights guselkumab's impact on Crohn's endoscopic healing

In a major advance for patients with Crohn's disease, a new study led by researchers at Mount Sinai Health System found that guselkumab, a medication with a mechanism of action that is new to inflammatory bowel disease (IBD) treatment, outperformed an established standard of care in promoting intestinal healing and symptom relief.

18 Jul 2025

Study identifies SDR42E1's role in vitamin D pathway

Vitamin D is not only an essential nutrient, but also the precursor of the hormone calcitriol, indispensable for health: it regulates the uptake of phosphate and calcium necessary for bones by the intestines, as well as cell growth and the proper function of muscles, nerve cells, and the immune system.

18 Jul 2025

Chronic venous insufficiency linked to increased cardiovascular disease and mortality risk

In light of reports from the White House that President Donald J. Trump has been diagnosed with Chronic Venous Insufficiency (CVI), the American Heart Association is sharing important information on the condition and its association with cardiovascular risk factors, disease and increased risk of death.

18 Jul 2025

Specially engineered antibody delivers RNA therapy to treatment-resistant tumors

A specially engineered antibody capable of delivering RNA therapies to hard-to-reach, treatment-resistant tumors significantly shrank tumor size and improved survival in animal models, according to a study published July 16 in Science Translational Medicine.

17 Jul 2025

Study casts doubt on a widely used shortcut in rectal cancer drug trials

A new study by a Tulane University researcher casts doubt on a widely used shortcut in rectal cancer drug trials, raising concerns that some treatments may be fast-tracked for approval without evidence they help patients live longer.

17 Jul 2025

Galectin-3 identified as key driver of chemoresistance in pancreatic cancer

Pancreatic cancer is often diagnosed at an advanced stage and is characterized by a poor prognosis and rising mortality.

17 Jul 2025

How can super-resolution technology help study neurotransmission?

Discover how super-resolution technology can be used to sudy neurotransmission at inhibitory synapses.

From Bruker Nano Surfaces and Metrology 17 Jul 2025

Robotic-assisted neuroendovascular aneurysm embolization shows promising 6-month results

The six-month follow-up results from the pioneering trial of robotic-assisted neuroendovascular aneurysm embolization using the CorPath GRX system were presented today by Vitor Pereira, MD on behalf of the investigators at the Society of NeuroInterventional Surgery's (SNIS) 22nd Annual Meeting.

17 Jul 2025

OmicsTweezer offers breakthrough in analyzing tumor microenvironments

Researchers have developed a powerful new tool that makes it easier to study the mix of cell types in human tissue, which is crucial for understanding diseases such as cancer.

17 Jul 2025

endTB-Q trial highlights importance of individualized regimens

Some patients with highly drug-resistant tuberculosis could benefit from a shorter treatment with fewer drugs while others may warrant more aggressive therapy, according to the findings of a new study led by an international group of researchers including scientists from Harvard Medical School and conducted across six countries in Asia, Africa, and South America.

17 Jul 2025

Chemotherapy may trigger inflammatory response that fuels bladder cancer resistance

Chemotherapy used to target and kill bladder cancer cells may trigger an inflammatory response that ultimately may make the cancer more resistant to treatment, according to new research from scientists at Houston Methodist.

16 Jul 2025

Unlocking bacterial genomes to develop tailored probiotic therapies

Probiotics are emerging tools used by neonatal intensive care units to promote healthy outcomes and prevent intestinal diseases such as necrotizing enterocolitis.

16 Jul 2025

Music therapy approach can ease distress in dementia patients

A new treatment that uses music therapy on dementia wards could improve care and support for some of the NHS's most vulnerable patients.

16 Jul 2025

Prestigious Stephenson Scholar Grants support cutting-edge pancreatic cancer studies

The Stephenson Global Pancreatic Cancer Research Institute and its partner City of Hope, one of the country's largest and most advanced cancer research and treatment organizations, today announced the six inaugural recipients of the prestigious Stephenson Scholar Grants, awarding $5.25 million to support high-impact research aimed at transforming the understanding, early detection and treatment of pancreatic cancer.

16 Jul 2025

New research offers hope to preserve vision in autosomal dominant optic atrophy

Autosomal dominant optic atrophy (ADOA), the most common genetic optic neuropathy, is an insidious disease. It often presents slowly during childhood by way of blurry vision, trouble reading or focusing, and sometimes only as a failed vision test.

16 Jul 2025

Harvard researchers uncover how the brain directs blood flow in real time

All day long, our brains carry out complicated and energy-intensive tasks such as remembering, solving problems, and making decisions.

16 Jul 2025

Gut-brain axis in eating disorders offers new treatment potential

Understanding the gut-brain axis is key to addressing eating disorders. This study highlights microbiota's influence and emerging therapeutic approaches.

16 Jul 2025

Research unravels the immune secrets of a cured pediatric rhabdoid tumor

Although relatively rare, many childhood cancers remain life-threatening and lack effective personalized treatments. Rhabdoid tumors are among these fatal cancers and can develop in various tissues and organs.

16 Jul 2025

New insights into depressive symptoms in premature ovarian insufficiency

Premature menopause has been described as a life-changing diagnosis with profound physical, psychological, and social consequences. Affected women not only experience the effects of estrogen deficiency, but they also experience the unanticipated loss of reproductive function.

16 Jul 2025

Yoga, Tai Chi, walking and jogging found to improve sleep and ease insomnia

Yoga, Tai Chi, walking and jogging may be the best forms of exercise to improve sleep quality and ease insomnia, suggest the findings of a comparative pooled data analysis published in the online journal BMJ Evidence Based Medicine.

15 Jul 2025