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Managing menopause: The 2023 toolkit for healthcare practitioners

The authors of the revised 2023 Toolkit extracted key recommendations from professional guidelines and positions as well as consensus statements on menopause and related conditions that have emerged since 2014.

1 Nov 2023

How next-gen sequencing is changing antibody drug discovery

New study outlines how next-generation sequencing (NGS) and machine-learning methods can revolutionize antibody discovery, particularly against SARS-CoV-2. The research demonstrates that NGS provides greater epitopic and paratopic diversity, enabling more effective identification and prioritization of therapeutic antibodies.

31 Oct 2023

Promising new drug target for triple-negative breast cancer identified

Improving treatments for triple-negative breast cancer (TNBC), an aggressive tumor with very poor prognosis and limited therapeutic targets, has been challenging.

30 Oct 2023

Modular nanoparticles developed for targeted drug delivery and neutralizing biological agents

Engineers at the University of California San Diego have developed modular nanoparticles that can be easily customized to target different biological entities such as tumors, viruses or toxins.

30 Oct 2023

Scientists identify mechanism causing deadly blood clots after some COVID-19 vaccines

A mechanism that led some patients to experience cases of deadly clotting following some types of Covid-19 vaccination has been identified in new research.

30 Oct 2023

Scientists identify mechanism of alcohol withdrawal headaches

About 283 million people worldwide suffer from alcohol use disorder, a debilitating health challenge for which limited therapeutic options are available. The cost to society is estimated at greater than $2 trillion annually.

30 Oct 2023

New omicron sublineages surge, but Pfizer-BioNTech bivalent booster retains effectiveness

The efficacy of the bivalent Pfizer-BioNTech COVID-19 messenger ribonucleic acid (mRNA) vaccine BNT162b2 BA.4/5.

30 Oct 2023

How does the Mediterranean diet impact insulin resistance and sensitivity in obese individuals?

Researchers evaluate the associations between adherence to the Mediterranean diet, insulin secretion, resistance, and sensitivity in obese individuals.

30 Oct 2023

New study highlights risks of anti-ERBB2 cancer drugs during pregnancy

Study finds that anti-ERBB2 inhibitors used in breast cancer treatment pose significant risks to pregnancy and fetal health, including higher likelihoods of congenital defects and intrauterine growth restriction. Researchers recommend careful monitoring and possibly discontinuing these drugs during pregnancy despite their effectiveness against cancer.

29 Oct 2023

Receptor structure-based virtual screening identifies a promising p38α inhibitor

Announcing a new publication for Acta Materia Medica journal. Mitogen-activated protein kinases (MAPKs) are a group of serine-threonine protein kinases that can be activated by extracellular stimuli.

27 Oct 2023

Imperial researchers discover hidden mechanism behind feeling touch

Imperial researchers have discovered a hidden mechanism within hair follicles that allow us to feel touch.

27 Oct 2023

New ERC-funded research project aims to develop targeted treatments for chronic wounds and cancer

the Freiburg University Medical Center and member of the Medical Faculty at the University of Freiburg, has received a European Research Council (ERC) Starting Grant from the European Commission.

27 Oct 2023

New treatment combination shows promise for metastatic colorectal cancer patients with rare genetic mutation

An international Phase 3 clinical trial found that metastatic colorectal cancer patients with a rare genetic tumor mutation called KRAS G12C experienced superior progression-free survival rates compared to standard of care when offered a combination treatment of KRAS inhibitor sotorasib and monoclonal antibody panitumumab.

27 Oct 2023

New bioreactor could accelerate access to cancer-killing immunotherapy

A new tool to rapidly grow cancer-killing white blood cells could advance the availability of immunotherapy, a promising therapy which harnesses the power of the body's immune response to target cancer cells.

26 Oct 2023

In acute myocardial infarction patients, does adding a traditional Chinese medicine compound to standard treatments improve outcomes?

Researchers investigated whether Tongxinluo, a Chinese medicinal compound, could improve clinical outcomes among ST-segment elevation myocardial infarction patients.

26 Oct 2023

NF-κB activation during COVID-19 and its impact on patients with hypertension

Researchers review the role of NF-κB activation in the replication of SARS-CoV-2 and the impact of COVID-19 medications on NF-κB activation.

25 Oct 2023

Scientists develop new method to control brain activity with light

Studying the brain remains one of the most challenging endeavors in neuroscience. Researchers have explored various methods for live imaging and stimulation of deep brain activity.

25 Oct 2023

Omicron's edge: boosters pressure SARS-CoV-2 to adapt and evolve

The effects of vaccine booster doses on the adaptive evolution of the virus.

25 Oct 2023

Red grape polyphenol, resveratrol: a multifaceted therapeutic powerhouse under review

The therapeutic potential of resveratrol, a red grape polyphenol.

25 Oct 2023

BA.2.86 Omicron sub-variant shows high receptor affinity but moderate neutralization resistance

Study investigates the receptor affinity and antigenicity of the SARS-CoV-2 Omicron BA.2.86 variant, revealing that it does not show higher resistance to neutralization by human sera than other recent variants. Despite its high number of mutations and receptor affinity, the variant is slightly more sensitive to neutralization than the EG.5.1 variant, warranting continued surveillance.

24 Oct 2023

Receptor News and Research

Managing menopause: The 2023 toolkit for healthcare practitioners

How next-gen sequencing is changing antibody drug discovery

Promising new drug target for triple-negative breast cancer identified

Modular nanoparticles developed for targeted drug delivery and neutralizing biological agents

Scientists identify mechanism causing deadly blood clots after some COVID-19 vaccines

Scientists identify mechanism of alcohol withdrawal headaches

New omicron sublineages surge, but Pfizer-BioNTech bivalent booster retains effectiveness

How does the Mediterranean diet impact insulin resistance and sensitivity in obese individuals?

New study highlights risks of anti-ERBB2 cancer drugs during pregnancy

Receptor structure-based virtual screening identifies a promising p38α inhibitor

Imperial researchers discover hidden mechanism behind feeling touch

New ERC-funded research project aims to develop targeted treatments for chronic wounds and cancer

New treatment combination shows promise for metastatic colorectal cancer patients with rare genetic mutation

New bioreactor could accelerate access to cancer-killing immunotherapy

In acute myocardial infarction patients, does adding a traditional Chinese medicine compound to standard treatments improve outcomes?

NF-κB activation during COVID-19 and its impact on patients with hypertension

Scientists develop new method to control brain activity with light

Omicron's edge: boosters pressure SARS-CoV-2 to adapt and evolve

Red grape polyphenol, resveratrol: a multifaceted therapeutic powerhouse under review

BA.2.86 Omicron sub-variant shows high receptor affinity but moderate neutralization resistance

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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