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Cleveland Clinic researchers win grants to study ethical issues involving brain surgery

The NIH BRAIN Initiative has awarded two Cleveland Clinic researchers grants to study ethical issues involving brain surgery, as part of the first neuroethics grants awarded by the initiative.

31 Oct 2017

Cleveland Clinic researcher awarded $2.6 million grant to create innovative models of colorectal cancer

Cleveland Clinic researcher Emina Huang, M.D., a colorectal surgeon in the Digestive Disease and Surgery Institute and a staff member in the Lerner Research Institute's Department of Stem Cell Biology and Regenerative Medicine, has been awarded a collaborative five-year, $2.6 million grant from the National Cancer Institute to create innovative models of colorectal cancer that will enhance understanding of how the disease develops and spreads.

31 Oct 2017

University of Pittsburgh research collaboration works toward saving more organs for transplants

Each year, the United States suffers an extreme shortage of organ donations, with only a quarter of patients in need receiving a transplant. Many transplantable organs are lost when a donor's heart fails, and the organs stop receiving vital blood flow.

31 Oct 2017

Infusions of cord blood cells can help improve motor function in children with cerebral palsy

An infusion of cells from a child's own umbilical cord blood appears to improve brain connectivity and motor function in children with spastic cerebral palsy, according to a randomized clinical trial published this week by Stem Cells Translational Medicine.

30 Oct 2017

Kidney transplantation may offer survival benefit for patients on long-term dialysis

A new study finds that kidney transplantation prolongs the lives of not only patients who have recently initiated dialysis, but also those who have been undergoing dialysis for more than a decade.

27 Oct 2017

Updated guidelines offer support for appropriate, safe use of accelerated partial-breast irradiation

Cleveland Clinic researcher Chirag Shah, M.D., led the development of updated guidelines for the appropriate and safe utilization of accelerated partial-breast irradiation. The guidelines are published online in the journal, Brachytherapy.

26 Oct 2017

New review addresses aspects of nutrition in liver transplant candidates with cirrhosis

Poor nutrition is common in patients with liver failure, or cirrhosis, and it can lead to muscle wasting, weakness, fatigue, and worse outcomes before and after patients undergo liver transplantation.

26 Oct 2017

Report: Overall burden of kidney disease remains high in the U.S.

According to an annual data report from the United State Renal Data System, the overall burden of kidney disease remains high in U.S. with the rates of kidney failure requiring dialysis or kidney transplantation ranking among the highest in the world.

26 Oct 2017

Scientists explore popular pre-heart transplant therapy’s impact on kidney function

Scientists, nephrologists and cardiac surgeons from The Feinstein Institute for Medical Research and Northwell Health's Department of Internal Medicine, Cardiology and Cardio-Thoracic Surgery examined the impact of a popular pre-heart transplant therapy on the kidney in a study published today by The Clinical Journal of the American Society of Nephrology.

26 Oct 2017

VICC selected to administer FDA-approved CAR T therapy for treatment of lymphoma patients

Vanderbilt-Ingram Cancer Center has been selected as one of the few authorized treatment centers in the United States approved to administer the first FDA- approved chimeric antigen receptor T cell (CAR T) therapy for treatment of adult patients with a specific type of lymphoma.

25 Oct 2017

Researchers find rare genetic variants that may help explain longevity in some CF patients

Cystic fibrosis is an inherited disorder caused by genetic mutations that disrupt the normal movement of chloride in and out of cells. Among other health problems, cystic fibrosis compromises the lungs' ability to fight infection and breathe efficiently, making it the most lethal genetic disease in the Caucasian population. Patients have an average lifespan of just 30 to 40 years.

25 Oct 2017

Researchers develop new way to genetically engineer T cells for treating leukemia relapse

Researchers at Fred Hutchinson Cancer Research Center and the University of Washington have developed a novel way to genetically engineer T cells that may be effective for treating and preventing leukemia relapse.

25 Oct 2017

VUMC reaches new milestone after performing 2,000th liver transplant

This month, Vanderbilt University Medical Center performed its 2,000th liver transplant, another milestone for one of the largest liver transplant programs in the Southeast.

20 Oct 2017

Study examines risk of using liver organs from hepatitis C positive donors

Use of liver organs from selected hepatitis C positive donors should be considered due to modest risk of hepatitis C transmission and the availability of safe and effective direct‐acting antiviral therapies, according to research presented this week at The Liver Meeting - held by the American Association for the Study of Liver Diseases.

20 Oct 2017

Increased use of split liver transplantation could decrease pediatric waitlist deaths

A new study presented this week at The Liver Meeting - held by the American Association for the Study of Liver Diseases - found that increased utilization of split liver transplantation (sharing a donor liver between one pediatric and one adult patient) could decrease the number of children who die awaiting liver transplantation without decreasing liver transplantation access for adult patients.

20 Oct 2017

Study finds rise in pregnancy rates among women with chronic liver disease

A new study presented this week at The Liver Meeting – held by the American Association for the Study of Liver Diseases – found that the overall number of pregnancies in women with chronic liver disease or following liver transplantation has risen over the past 30 years.

20 Oct 2017

Kidney failure linked to lower quality of life, psychosocial challenges in young adults

Kidney failure is associated with lower quality of life in young people and limited employment, independence, and relationships compared with healthy peers, according to an analysis appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology

20 Oct 2017

Families stop donation of organs from deceased relatives who are registered donors

Hundreds of families across England block the donation of organs from deceased relatives, despite the deceased having chosen to sign the Organ Donation Register.

19 Oct 2017

Cascade of costs could push new gene therapy above $1 million per patient

Outrage over the high cost of cancer care has focused on skyrocketing drug prices, including the $475,000 price tag for the country's first gene therapy, Novartis' Kymriah, a leukemia treatment approved in August.

17 Oct 2017

Surgeries performed later in the day linked to increased risk of complications

A new study published in Neurosurgery finds that patients who undergo a neurosurgical procedure with surgical start times between 9 pm and 7 am are at an increased risk of developing complications compared to patients with a surgical start time earlier in the day.

13 Oct 2017

Transplant News and Research

Cleveland Clinic researchers win grants to study ethical issues involving brain surgery

Cleveland Clinic researcher awarded $2.6 million grant to create innovative models of colorectal cancer

University of Pittsburgh research collaboration works toward saving more organs for transplants

Infusions of cord blood cells can help improve motor function in children with cerebral palsy

Kidney transplantation may offer survival benefit for patients on long-term dialysis

Updated guidelines offer support for appropriate, safe use of accelerated partial-breast irradiation

New review addresses aspects of nutrition in liver transplant candidates with cirrhosis

Report: Overall burden of kidney disease remains high in the U.S.

Scientists explore popular pre-heart transplant therapy’s impact on kidney function

VICC selected to administer FDA-approved CAR T therapy for treatment of lymphoma patients

Researchers find rare genetic variants that may help explain longevity in some CF patients

Researchers develop new way to genetically engineer T cells for treating leukemia relapse

VUMC reaches new milestone after performing 2,000th liver transplant

Study examines risk of using liver organs from hepatitis C positive donors

Increased use of split liver transplantation could decrease pediatric waitlist deaths

Study finds rise in pregnancy rates among women with chronic liver disease

Kidney failure linked to lower quality of life, psychosocial challenges in young adults

Families stop donation of organs from deceased relatives who are registered donors

Cascade of costs could push new gene therapy above $1 million per patient

Surgeries performed later in the day linked to increased risk of complications

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