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Measuring kidney function and damage may help predict people at risk for heart disease

Simple measures of kidney function and damage may be just as good at predicting who is at risk for heart failure and death from heart attack and stroke as traditional tests of cholesterol levels and blood pressure, new Johns Hopkins Bloomberg School of Public Health-led research suggests.

29 May 2015

MIT, UCSD researchers use probiotics to detect cancer in the liver

Engineers at MIT and the University of California at San Diego have devised a new way to detect cancer that has spread to the liver, by enlisting help from probiotics — beneficial bacteria similar to those found in yogurt.

29 May 2015

RI-MUHC researchers receive $1.5 million to develop glutamate biosensor platform for brain diseases

In the human brain and retina, glutamate is an important messenger that carries information from one neuron to another. The level of glutamate transmitted between neurons is crucial to cell communication: too high and neurons die, too low and the information is not communicated properly. In either case this can contribute to neurological diseases including stroke, glaucoma, and Alzheimer's.

29 May 2015

Scientists reveal why lone kidney gets bigger when the other one is lost

Scientists have found an explanation for the century-old observation that if you end up with just one kidney, the lone organ gets bigger.

29 May 2015

Differences in brain expression of RORA protein levels may lead to sex bias in autism

George Washington University researcher Valerie Hu, Ph.D., has found an important sex-dependent difference in the level of RORA protein in brain tissues of males and females. Specifically, females without autism have a slightly higher level of RORA in the frontal cortex of the brain than males without autism, while the levels of the protein are comparably lower in the brain of both males and females with autism.

29 May 2015

Study reveals new molecular mechanism that helps protect genome from harmful effect of UV radiations

Researchers have uncovered a new molecular mechanism whereby human cells protect their genome from the detrimental effect of UV radiation and govern DNA replication in cellular mitosis, which, when it malfunctions, leads to harmful results.

29 May 2015

Monoclonal antibody nivolumab improves survival rates of melanoma patients

The monoclonal antibody nivolumab has shown promise as a therapeutic agent, particularly by improving the survival rates of melanoma patients. Jeffrey S. Weber, M.D., Ph.D., director of the Donald A. Adam Comprehensive Melanoma Research Center at Moffitt Cancer Center will be presenting data from a retrospective analysis of the safety of nivolumab in 4 ongoing phase I-III studies in melanoma patients at the 2015 American Society of Clinical Oncology Annual Meeting in Chicago.

29 May 2015

MEDI4736 and tremelimumab combination shows acceptable safety, potential efficacy in NSCLC patients

Advanced non-small cell lung cancer (NSCLC) patients have few effective treatment options and low 5-year survival rates. The checkpoint inhibitors MEDI4736 and tremelimumab have both demonstrated acceptable safety and potential efficacy when used as single-agents in several different types of cancer.

29 May 2015

Researchers find weak spot in some antibiotic-resistant bacteria

Using a complex modeling program that helps analyze the physical dynamics of large, structurally complex protein molecules, a research team has made progress towards finding a weak spot in the architecture of a group of enzymes that are essential to antibiotic resistance in a number of bacteria.

29 May 2015

Therapy for genetically-caused emphysema slows progression of lung disease

A landmark clinical study in the Lancet provides convincing evidence that a frequently overlooked therapy for genetically-caused emphysema is effective and slows the progression of lung disease.

29 May 2015

Proteomics research market estimated to reach $1.6 billion this year

Pharmaceutical companies and diagnostics companies spend billions developing new drugs and tests, and this is translating into a sizeable market for the instruments that can assist them. This according to Kalorama Information, a healthcare market research publisher. Kalorama Information said instruments such as mass spectrometry, electrophoresis and liquid chromatography that can assist in the identification of drug targets and the validation of biomarkers, are in demand.

29 May 2015

Novel discovery offers new insight into why women more likely than men to develop MS

An innocent mistake made by a graduate student in a Northwestern Medicine lab (she accidentally used male mice instead of female mice during an experiment) has led scientists to a novel discovery that offers new insight into why women are more likely than men to develop autoimmune diseases such as multiple sclerosis (MS).

28 May 2015

Researchers suggest new target for treating BRAF inhibitor-resistant melanoma tumors

A new collaborative study led by researchers at Sanford-Burnham Medical Research Institute, published today in Cell Reports, provides new insight into the molecular changes that lead to resistance to a commonly prescribed group of drugs called BRAF inhibitors.

28 May 2015

Amway releases BodyKey by Nutrilite tool that uses genetic test to determine weight management approach

When it comes to choosing a weight management plan, research shows that one size does not fit all. That's why Amway introduced BodyKey by Nutrilite, a weight management program that uses a genetic test or a comprehensive assessment based on validated science to help consumers determine an ideal weight management approach.

28 May 2015

Functional foods help reduce obesity, control diabetes

The so called functional foods such as cactus pads, chia and soybean, when included in a balanced diet, help reduce obesity and control diabetes, says Nimbe Torres y Torres, from the Institute of Biomedical Research at the National Autonomous University of Mexico.

28 May 2015

Progression of different types of breast cancer influenced differently by tumor microenvironment

Our environment can have a major impact on how we develop, and it turns out it's no different for cancer cells. In work published today in Neoplasia, a team of researchers led by Associate Professor Mikala Egeblad at Cold Spring Harbor Laboratory found that two different mouse models of breast cancer progressed differently based on characteristics of the tumor microenvironment - the area of tissue in which the tumor is embedded.

28 May 2015

Airway and systemic inflammation predict COPD exacerbation

Researchers have found a link between increased airway and systemic inflammation and frequent exacerbations in patients with chronic obstructive pulmonary disease.

27 May 2015

Six research teams awarded grant to accelerate discovery of new drugs for brain, nervous system disorders

CQDM, Brain Canada and the Ontario Brain Institute award close to $8.5M to six (6) multi-disciplinary and multi-provincial research teams across Canada to address unmet needs in neuroscience within their Focus on Brain strategic initiative. To this amount, $1.5M is added from the various research entities involved as in-kind contributions.

27 May 2015

Ceres receives U.S. patent for genetic sequence obtained from soybean

Ceres, Inc., an agricultural biotechnology company, has been awarded a U.S. patent for a genetic sequence derived from soybean, covering uses of the gene in areas such as research, product development and plant transformation.

27 May 2015

Scorpion venom could kill cancer cells

When the toxin invades channels in the cells with this disease produces cellular damage until killing them.

27 May 2015

Protein C News and Research

Measuring kidney function and damage may help predict people at risk for heart disease

MIT, UCSD researchers use probiotics to detect cancer in the liver

RI-MUHC researchers receive $1.5 million to develop glutamate biosensor platform for brain diseases

Scientists reveal why lone kidney gets bigger when the other one is lost

Differences in brain expression of RORA protein levels may lead to sex bias in autism

Study reveals new molecular mechanism that helps protect genome from harmful effect of UV radiations

Monoclonal antibody nivolumab improves survival rates of melanoma patients

MEDI4736 and tremelimumab combination shows acceptable safety, potential efficacy in NSCLC patients

Researchers find weak spot in some antibiotic-resistant bacteria

Therapy for genetically-caused emphysema slows progression of lung disease

Proteomics research market estimated to reach $1.6 billion this year

Novel discovery offers new insight into why women more likely than men to develop MS

Researchers suggest new target for treating BRAF inhibitor-resistant melanoma tumors

Amway releases BodyKey by Nutrilite tool that uses genetic test to determine weight management approach

Functional foods help reduce obesity, control diabetes

Progression of different types of breast cancer influenced differently by tumor microenvironment

Airway and systemic inflammation predict COPD exacerbation

Six research teams awarded grant to accelerate discovery of new drugs for brain, nervous system disorders

Ceres receives U.S. patent for genetic sequence obtained from soybean

Scorpion venom could kill cancer cells

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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