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Researchers identify chemical compound that may short-circuit brain cell death in Parkinson's disease

In studies in mice, Johns Hopkins Medicine researchers say they have identified a chemical compound that stops the final events in the pathway linked to the death of brain cells in Parkinson's disease.

1 Jun 2022

Combination bNAb therapy may offer a future alternative to daily ART for people living with HIV

Individuals with HIV who began taking antiretroviral therapy (ART) in the early stages of infection achieved a lengthy period of HIV suppression without ART after receiving two broadly neutralizing anti-HIV antibodies (bNAbs), according to a small study published today in the journal Nature.

1 Jun 2022

People with food allergies less likely to become infected with SARS-CoV-2, study finds

A National Institutes of Health-funded study has found that people with food allergies are less likely to become infected with SARS-CoV-2, the virus that causes COVID-19, than people without them. In addition, while previous research identified obesity as a risk factor for severe COVID-19, the new study has identified obesity and high body mass index (BMI) as associated with increased risk for SARS-CoV-2 infection.

1 Jun 2022

Gene therapy for degenerative retinal disease has no safety concerns but fails to improve vision loss

A 28-patient phase 1 gene therapy clinical trial for the degenerative retinal disease Leber hereditary optic neuropathy (LHON) found no significant safety concerns; however, treatment failed to improve or slow vision loss, with even the highest dose. LHON affects the optic nerve, which carries visual signals from the light-sensing retina to the brain.

1 Jun 2022

Researchers identify molecular characteristics linked to increased likelihood of post-vaccination fatigue

Despite their strong effectiveness against SARS-CoV-2, mRNA-based COVID-19 vaccines are associated with adverse post-vaccination effects, such as fatigue; how can this be avoided? In a new study publishing May 31st in the open-access journal PLOS Biology, Ayesa Syenina of the Duke–NUS Medical School in Singapore and colleagues report that a new analysis of blood samples from people vaccinated for COVID-19 has identified distinct molecular characteristics linked to an increased likelihood of post-vaccination fatigue.

31 May 2022

Scientists develop new way to attack synovial sarcoma using an investigational drug

Researchers at Washington University School of Medicine in St. Louis have developed a way to attack synovial sarcoma - a rare tumor of soft tissues, such as ligaments and muscles - using an investigational drug that triggers cell death.

31 May 2022

Hennepin Healthcare researchers test an innovative way to help people quit smoking

Hennepin Healthcare Research Institute is testing an innovative way to help people quit smoking – by letting them bet on themselves and win real money.

27 May 2022

Study: Most clinicians do not follow recommendations against prescribing antibiotics for asymptomatic bacteriuria

An estimated 70 percent of primary care physicians reported in a survey that they would still prescribe antibiotics to treat asymptomatic infections based solely on a positive urine specimen.

27 May 2022

Multidisciplinary care improves outcomes from chronic kidney disease

It is generally agreed that a team of individuals with unique talents and skills offers the potential to achieve more than any person can achieve alone.

26 May 2022

Infants diagnosed with autism show differences in brain’s visual areas

Infants who were diagnosed with autism spectrum disorder (ASD) at 24 months old had differences in the visual processing areas of the brain that were apparent at 6 months old, according to a study funded by the National Institutes of Health.

26 May 2022

Researchers receive $8 million grant to prevent traumatic brain injury in military personnel

Researchers backed by an $8 million U.S. Department of Defense grant will explore how to better prevent traumatic brain injury, or TBI, in military personnel exposed to blast shock waves.

26 May 2022

Researchers focus on how bacterial cells adapt and resist antibiotics

Treatment of severe infections caused by pathogenic bacteria relies on ‘last resort’ antibiotics, but rising resistance by ‘superbugs’ to most clinically approved drugs leaves patients exposed to possible fatalities.

26 May 2022

Patient’s perspective on their physical well-being can help better predict cancer treatment outcomes

A breast cancer patient’s perspective on their physical well-being can provide a better indication of their response to cancer treatment than clinician-based tools, a new study has found, highlighting the importance of shared decision-making in the treatment process.

26 May 2022

Ketamine uses a previously unknown pathway to produce an antidepressant effect, study finds

For the 280 million people suffering from depression globally, relief cannot come fast enough. Monoaminergic antidepressants, including selective serotonin reuptake inhibitors (SSRIs) take weeks to months to take effect and do not work for more than one in three patients.

26 May 2022

Staying physically active before COVID-19 infection can help reduce disease severity

A consortium of Luxembourgish research institutions studying the national population have been looking to identify factors that may contribute to variations in severity of COVID-19 and its associated symptoms.

26 May 2022

Study uncovers a possible mechanism that links cerebrovascular disease and Alzheimer's

For more than 20 years, scientists have known that people with hypertension, diabetes, high cholesterol, or obesity have a higher likelihood of developing Alzheimer's disease.

25 May 2022

New imaging approach helps scientists build a complete picture of brain networks

Researchers at the Francis Crick Institute have developed an imaging technique to capture information about the structure and function of brain tissue at subcellular level – a few billionth of a metre, while also capturing information about the surrounding environment.

25 May 2022

HKUMed researchers report the effects of SARS-CoV-2 on bone metabolism

A research team led by Professor Kelvin Yeung Wai-kwok and Dr Jasper Chan Fuk-woo from the LKS Faculty of Medicine, The University of Hong Kong (HKUMed) discovered that SARS-CoV-2 infection can cause inflammatory activation of bone resorption cells, leading to severe bone loss during the acute and post-recovery phases of COVID-19.

25 May 2022

Using AI to Achieve Earlier Diagnosis of Pancreatic Cancer

In this interview, we talk to Takayuki Baba about ongoing research using artificial intelligence to achieve earlier diagnosis of pancreatic cancer.

24 May 2022

Emergency department plays vital role in investigating the accuracy of COVID-19 diagnostic tests

The Department of Emergency Medicine at Washington University School of Medicine in St. Louis played a key role in investigating the accuracy of many different types of COVID-19 diagnostic tests administered in real-life conditions.

23 May 2022

Medical Research News and Research

Researchers identify chemical compound that may short-circuit brain cell death in Parkinson's disease

Combination bNAb therapy may offer a future alternative to daily ART for people living with HIV

People with food allergies less likely to become infected with SARS-CoV-2, study finds

Gene therapy for degenerative retinal disease has no safety concerns but fails to improve vision loss

Researchers identify molecular characteristics linked to increased likelihood of post-vaccination fatigue

Scientists develop new way to attack synovial sarcoma using an investigational drug

Hennepin Healthcare researchers test an innovative way to help people quit smoking

Study: Most clinicians do not follow recommendations against prescribing antibiotics for asymptomatic bacteriuria

Multidisciplinary care improves outcomes from chronic kidney disease

Infants diagnosed with autism show differences in brain’s visual areas

Researchers receive $8 million grant to prevent traumatic brain injury in military personnel

Researchers focus on how bacterial cells adapt and resist antibiotics

Patient’s perspective on their physical well-being can help better predict cancer treatment outcomes

Ketamine uses a previously unknown pathway to produce an antidepressant effect, study finds

Staying physically active before COVID-19 infection can help reduce disease severity

Study uncovers a possible mechanism that links cerebrovascular disease and Alzheimer's

New imaging approach helps scientists build a complete picture of brain networks

HKUMed researchers report the effects of SARS-CoV-2 on bone metabolism

Using AI to Achieve Earlier Diagnosis of Pancreatic Cancer

Emergency department plays vital role in investigating the accuracy of COVID-19 diagnostic tests

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