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Myriad and Clovis ink deal on FDA-approved BRACAnalysis CDx test to identify patients with germline BRCA mutations for rucaparib treatment

Myriad Genetics, Inc. and Clovis Oncology, Inc. have announced a companion diagnostic collaboration to support a post-marketing regulatory commitment related to Clovis’ PARP inhibitor, Rubraca. Financial terms of the deal were not disclosed.

3 May 2017

Invivoscribe receives FDA approval for the LeukoStrat CDx FLT3 mutation assay companion diagnostic test for the selection of patients for Rydapt

Invivoscribe® Technologies Inc., a global company with more than 20 years of experience providing clonality and biomarker test solutions for the fields of oncology, personalized molecular diagnostics® and personalized molecular medicine®, today announces the premarket approval of LeukoStrat® CDx FLT3 Mutation Assay.

3 May 2017

Discovery of protein that causes liver disease brings hope for new treatments

In a world-first discovery, scientists at Sydney’s Westmead Institute for Medical Research have identified a protein that causes liver fibrosis (scarring), paving the way for new treatments for liver disease to be developed.

3 May 2017

Molecular drug imaging likely to benefit children with brain tumors

Brain cancers are difficult to treat, and it can be hard to predict whether a therapy will be effective. When the patient is a child, it's even more important to predict the potential effectiveness of a drug before beginning treatment.

3 May 2017

Noninvasive PET imaging may predict cancer patients’ immunotherapy response early

A noninvasive PET imaging method that measures granzyme B, a protein released by immune cells to kill cancer cells, was able to distinguish mouse and human tumors that responded to immune checkpoint inhibitors from those that did not respond early in the course of treatment.

1 May 2017

Study explores precision psychiatry approaches to improve outcomes for patients with depression

A new study in Personalized Medicine in Psychiatry explores how specific clinical and biological signals can help doctors select the most effective drug more quickly and with greater precision.

1 May 2017

Study: Artificial pancreas helps young children better control their diabetes

A pilot study among young children with Type 1 diabetes found that a University of Virginia-developed artificial pancreas helped study participants better control their condition.

28 Apr 2017

Unstable chromosomes in lung tumors increase risk of cancer relapse, study reveals

The New England Journal of Medicine and Nature has published the first findings from the Cancer Research UK-funded Tracking Cancer Evolution through Treatment (Rx), TRACERx, lung cancer study, which reveals the increase in the risk of cancer relapse when lung tumors have unstable chromosomes.

27 Apr 2017

AI key to driving precision medicine in cancer?

It is worth noting that in the U.S. and in many countries, digital pathology is still at a very early stage, compared to many other fields that were digitized 15 or 20 years ago such as radiology. There have been some barriers to the adoption of digital pathology such as regulatory challenges that are only just now being overcome. Recently, the FDA approved the use of whole slide imaging software for primary diagnostics.

27 Apr 2017

Research offers new way to improve nanopharmaceuticals for personalized medicine

In a newly published study in Nature Nanotechnology, the shape and geometry of nanoparticles can have a significant impact in modulating adverse injection reactions and offer realistic solutions for patients receiving nanopharmaceuticals—drug delivery systems specializing in microscopic-particle drug combinations.

27 Apr 2017

New technique dramatically accelerates search for new cancer treatments

A new technique developed at the University of Virginia School of Medicine will let a single cancer research lab do the work of dozens, dramatically accelerating the search for new treatments and cures.

26 Apr 2017

Personalized approach to pharmacotherapy may provide advances in treatment of panic disorders

Although drug therapy is the accepted first-line treatment for panic disorders, 17% to 64% of patients do not respond adequately and continue to exhibit one of the most common symptoms of PD, the panic attack.

26 Apr 2017

Researchers use novel phage therapy to treat patient infected with multidrug-resistant bacterium

Scientists and physicians at University of California San Diego School of Medicine, working with colleagues at the U.S. Navy Medical Research Center - Biological Defense Research Directorate, Texas A&M University, a San Diego-based biotech and elsewhere, have successfully used an experimental therapy involving bacteriophages -- viruses that target and consume specific strains of bacteria -- to treat a patient near death from a multidrug-resistant bacterium.

25 Apr 2017

Combination of genetics and experience gives each individual a unique sense of smell, study finds

Researchers from the Wellcome Trust Sanger Institute and their collaborators have shown that receptors in the noses of mice exposed to certain smells during life are different to genetically similar mice that lived without those smells.

25 Apr 2017

Study shows how gut microbiota may play role in effectiveness of chemotherapy drugs

The bacteria residing in your digestive tract, or your gut microbiota, may play an important role in your ability to respond to chemotherapy drugs in the clinic, according to a new study by scientists at the University of Massachusetts Medical School.

25 Apr 2017

$Women at highest genetic risk for fracture benefit most from hormone therapy, study finds$

Women at highest genetic risk for fracture benefit most from hormone therapy, study finds

Women at the highest genetic risk for fracture benefit the most from hormone therapy, according to a first-of-its-kind study led by researchers at the University at Buffalo.

24 Apr 2017

Study shows how brain genes influence food intake and dietary preferences

Have you ever wondered why you keep eating certain foods, even if you know they are not good for you? Gene variants that affect the way our brain works may be the reason, according to a new study. The new research could lead to new strategies to empower people to enjoy and stick to their optimal diets.

24 Apr 2017

Transgenic fruit flies can shed light on genetic mutations that underlie kidney disease in humans

An off-the-shelf dietary supplement available for pennies per dose demonstrated the ability to reverse cellular damage linked to specific genetic mutations in transgenic fruit flies, an experimental model of genetic mutation-induced renal cell injury that features striking similarities to humans, a Children's National Health System research team reports April 20 in Journal of the American Society of Nephrology.

21 Apr 2017

Study finds high degree of discordance between Myriad Genetics and public database in BRCA1 and BRCA2 variant classifications

Myriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, today announced that new data comparing BRCA1 and BRCA2 variant classifications between Myriad Genetics and a commonly used public genetic database was published in the journal The Oncologist.

21 Apr 2017

New model may provide vital insights into life-saving treatment for CMV infection

At-risk patients, such as those with HIV or transplant recipients, could benefit from potentially life-saving study carried out by a University of Surrey led group of international researchers.

21 Apr 2017

Precision Medicine News and Research

Myriad and Clovis ink deal on FDA-approved BRACAnalysis CDx test to identify patients with germline BRCA mutations for rucaparib treatment

Invivoscribe receives FDA approval for the LeukoStrat CDx FLT3 mutation assay companion diagnostic test for the selection of patients for Rydapt

Discovery of protein that causes liver disease brings hope for new treatments

Molecular drug imaging likely to benefit children with brain tumors

Noninvasive PET imaging may predict cancer patients’ immunotherapy response early

Study explores precision psychiatry approaches to improve outcomes for patients with depression

Study: Artificial pancreas helps young children better control their diabetes

Unstable chromosomes in lung tumors increase risk of cancer relapse, study reveals

AI key to driving precision medicine in cancer?

Research offers new way to improve nanopharmaceuticals for personalized medicine

New technique dramatically accelerates search for new cancer treatments

Personalized approach to pharmacotherapy may provide advances in treatment of panic disorders

Researchers use novel phage therapy to treat patient infected with multidrug-resistant bacterium

Combination of genetics and experience gives each individual a unique sense of smell, study finds

Study shows how gut microbiota may play role in effectiveness of chemotherapy drugs

Women at highest genetic risk for fracture benefit most from hormone therapy, study finds

Study shows how brain genes influence food intake and dietary preferences

Transgenic fruit flies can shed light on genetic mutations that underlie kidney disease in humans

Study finds high degree of discordance between Myriad Genetics and public database in BRCA1 and BRCA2 variant classifications

New model may provide vital insights into life-saving treatment for CMV infection

Event guide: The 4th Precision Medicine in Inflammatory Bowel Disease Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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