Genetic News and Research

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Aviir to extend comprehensive inherited cardiovascular disease genetic test menu

Aviir Inc., a biotechnology company dedicated to the prevention of cardiovascular disease through innovative laboratory tests, announced that it will be extending its offered services with comprehensive inherited cardiovascular disease genetic test menu.

8 May 2013

New VLP vaccine candidate produced for H7N9 virus

Medicago Inc., a biopharmaceutical company focused on developing highly effective and competitive vaccines based on proprietary manufacturing technologies and Virus-Like Particles, today announced that it has successfully produced a new VLP vaccine candidate for the H7N9 virus that is responsible for the current influenza outbreak in China.

8 May 2013

IDIBELL signs patent licensing agreement with Minoryx

The Bellvittge Biomedical Research Institute has signed a licensing agreement with the Spanish biotechnology company Minoryx of a patent for the treatment of X-linked adrenoleukodystrophy, a rare serious neurodegenerative disease which has no effective treatment.

8 May 2013

Study shows turning up few microRNAs may offer much anti-breast-cancer activity

A University of Colorado Cancer Center study recently published in the journal Cell Death & Disease shows that turning up a few microRNAs a little may offer as much anti-breast-cancer activity as turning up one microRNA a lot - and without the unwanted side effects.

8 May 2013

Research discovery may lead to effective new treatments for neurodegenerative disease

UCLA researchers led by Drs. Peiyee Lee and Richard Gatti at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have used induced pluripotent stem cells to advance disease-in-a-dish modeling of a rare genetic disorder, Ataxia Telangiectasia.

8 May 2013

Immunoglobulin fails to meet co-primary endpoints in Phase III clinical study, Baxter reports

Baxter International Inc. today announced that its Phase III clinical study of immunoglobulin did not meet its co-primary endpoints of reducing cognitive decline and preserving functional abilities in patients with mild to moderate Alzheimer's disease.

From Baxter International Inc. 8 May 2013

New skin cancer drug successfully tested in humans

A new class of drug targeting skin cancer's genetic material has been successfully tested in humans for the first time, opening the way to new treatments for a range of conditions from skin cancers to eye diseases.

8 May 2013

Study to examine role of arts, humanities in improving mental health and well-being

An innovative study led by The University of Nottingham is to investigate whether arts and humanities can help improve the mental health and well-being of patients and carers alike.

8 May 2013

Biomedical engineers grow 3D human heart muscle that acts just like natural tissue

Duke University biomedical engineers have grown three-dimensional human heart muscle that acts just like natural tissue. This advancement could be important in treating heart attack patients or in serving as a platform for testing new heart disease medicines.

7 May 2013

Complex network of molecules controls formation and activity of neuronal connections

Environment moulds behaviour - and not just that of people in society, but also at the microscopic level. This is because, for their function, neurons are dependent on the cell environment, the so-termed extracellular matrix.

7 May 2013

Scientists halt tumour development through genetic manipulation of cytoskeleton in fly tissues

Cancer is a complex disease, in which cells undergo a series of alterations, including changes in their architecture; an increase in their ability to divide, to survive and to invade new tissues or metastasis.

7 May 2013

Aileron Therapeutics concludes first-in-human study of ALRN-5281 Stapled Peptide drug

Aileron Therapeutics, Inc. today announced the completion of the first-in-human study of its lead Stapled Peptide drug, ALRN-5281, a proprietary, long-acting growth-hormone-releasing hormone (GHRH) agonist for treating orphan endocrine disorders, including adult growth hormone (GH) deficiency and human immunodeficiency virus (HIV) lipodystrophy, as well as broader patient populations involving a wide variety of metabolic/endocrine diseases.

7 May 2013

Kinase inhibitors: an interview with Jan Hoflack, CSO of Oncodesign

Kinase inhibitors are molecules that block the activity of kinases. Kinases are a specific class of enzymes. They are extremely important in signal transduction processes in the human body meaning that they actually regulate most of the physiological processes that take place in the body.

7 May 2013

Scientists uncover unknown virulence factor in respiratory pathogen

To infect its host, the respiratory pathogen Pseudomonas aeruginosa takes an ordinary protein usually involved in making other proteins and adds three small molecules to turn it into a key for gaining access to human cells.

7 May 2013

Royal Society elects scientists from JIC for advances in antibiotic discovery and in crop improvement

Two scientists from the John Innes Centre have been elected as Fellows of the Royal Society, the premier scientific accolade in the UK. Their breakthroughs in fundamental research have pioneered advances in antibiotic discovery and in crop improvement from which we all benefit.

6 May 2013

Tipsheet of story ideas from Cedars-Sinai Medical Center

In an effort to better protect women from heart disease, Irene Pollin, a widely respected public health advocate who founded the nation's first organization dedicated to preventing heart disease in women, has donated $10 million to the Barbra Streisand Women's Heart Center at the Cedars-Sinai Heart Institute.

6 May 2013

Scientists create animal models by altering specific genes associated with a given disease

Whitehead Institute Founding Member Rudolf Jaenisch, who helped transform the study of genetics by creating the first transgenic mouse in 1974, is again revolutionizing how genetically altered animal models are created and perhaps even redefining what species may serve as models.

6 May 2013

Experts report new outbreaks and increased spread of Cassava Brown Streak Disease

Cassava experts are reporting new outbreaks and the increased spread of Cassava Brown Streak Disease or CBSD, warning that the rapidly proliferating plant virus could cause a 50 percent drop in production of a crop that provides a significant source of food and income for 300 million Africans.

6 May 2013

High levels of collagen in breasts are associated with breast cancer metastasis

Researchers at Washington University School of Medicine in St. Louis have discovered why breast cancer patients with dense breasts are more likely than others to develop aggressive tumors that spread.

6 May 2013

Study: Combination of chemotherapy and nerve-protecting agents can prevent anemia

Cancer chemotherapy can cause peripheral neuropathy-nerve damage often resulting in pain and muscle weakness in the arms and legs. Now, researchers at Albert Einstein College of Medicine of Yeshiva University have discovered that chemo also induces an insidious type of nerve damage inside bone marrow that can cause delays in recovery after bone marrow transplantation.

6 May 2013

Genetic News and Research

Aviir to extend comprehensive inherited cardiovascular disease genetic test menu

New VLP vaccine candidate produced for H7N9 virus

IDIBELL signs patent licensing agreement with Minoryx

Study shows turning up few microRNAs may offer much anti-breast-cancer activity

Research discovery may lead to effective new treatments for neurodegenerative disease

Immunoglobulin fails to meet co-primary endpoints in Phase III clinical study, Baxter reports

New skin cancer drug successfully tested in humans

Study to examine role of arts, humanities in improving mental health and well-being

Biomedical engineers grow 3D human heart muscle that acts just like natural tissue

Complex network of molecules controls formation and activity of neuronal connections

Scientists halt tumour development through genetic manipulation of cytoskeleton in fly tissues

Aileron Therapeutics concludes first-in-human study of ALRN-5281 Stapled Peptide drug

Kinase inhibitors: an interview with Jan Hoflack, CSO of Oncodesign

Scientists uncover unknown virulence factor in respiratory pathogen

Royal Society elects scientists from JIC for advances in antibiotic discovery and in crop improvement

Tipsheet of story ideas from Cedars-Sinai Medical Center

Scientists create animal models by altering specific genes associated with a given disease

Experts report new outbreaks and increased spread of Cassava Brown Streak Disease

High levels of collagen in breasts are associated with breast cancer metastasis

Study: Combination of chemotherapy and nerve-protecting agents can prevent anemia

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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