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New software package employs deep-learning algorithms to analyze T-cell receptor sequencing data

Researchers at the Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center have developed DeepTCR, a software package that employs deep-learning algorithms to analyze T-cell receptor (TCR) sequencing data. T-cell receptors are found on the surface of immune T cells.

5 Apr 2021

Researchers Identify potent small molecule inhibitors against SARS-CoV-2

A team of scientists from the USA and Sweden has recently screened 8 million small molecule inhibitors against SARS-CoV-2.

5 Apr 2021

Study shows rates of prolonged visits for pediatric mental health ED visits increased over a decade

Rates of prolonged visits for pediatric mental health emergency department visits increased over a decade, in contrast to non-mental health visits for which visit times remained stable, according to a study published in the journal Pediatrics.

5 Apr 2021

Genome analysis of more than 53,000 people offers valuable insights into dangerous diseases

A new analysis of the entire genetic makeup of more than 53,000 people offers a bonanza of valuable insights into heart, lung, blood and sleep disorders, paving the way for new and better ways to treat and prevent some of the most common causes of disability and death.

5 Apr 2021

Study paves way for effective monitoring of chemotherapeutic drug level in cancer patients

Cancer is the world's second deadliest disease which contributes towards the fatality of over 10 million people per year.

3 Apr 2021

New approach to CAR T gene therapy yields efficient and longer-lasting response against HIV

A UCLA research team has shown that using a truncated form of the CD4 molecule as part of a gene therapy to combat HIV yielded superior and longer-lasting results in mouse models than previous similar therapies using the CD4 molecule.

3 Apr 2021

Maternal exposure to pesticides may lead to central nervous system tumors during childhood

Research published in the peer-reviewed journal Environmental Research suggests that exposure during pregnancy to a wide variety of pesticides may lead to the development of central nervous system tumors during childhood.

3 Apr 2021

Treatment resistance in triple-negative breast cancers linked to softer tissue environment

Researchers at the University of California, San Francisco, have discovered that aggressive, triple-negative breast cancers (TNBCs) can evade treatment by reorganizing and softening the collagen matrix that surrounds the cancer cells.

3 Apr 2021

Study uncovers novel mechanism in rare mutation associated with Alzheimer's

A novel mechanism has been identified that might explain why a rare mutation is associated with familial Alzheimer's disease in a new study by investigators at the University of Chicago.

3 Apr 2021

Video games may help improve surgical skills training for medical students

Video games offer students obvious respite from the stresses of studies and, now, a study from a University of Ottawa medical student has found they could benefit surgical skills training.

3 Apr 2021

50-state analysis finds excess deaths from COVID-19 and other causes in the U.S.

Extended surges in the South and West in the summer and early winter of 2020 resulted in regional increases in excess death rates, both from COVID-19 and from other causes, a 50-state analysis of excess death trends has found.

3 Apr 2021

Study: More than 60% of adult e-cigarette users in the U.S want to quit

More than 60% of U.S. adults who vape are interested in quitting, according to a study published today in JAMA Network Open by MUSC Hollings Cancer Center researchers.

3 Apr 2021

Many health and academic professionals consider leaving their jobs after COVID-19, finds study

Up to one in five employees at an academic medical institution are considering leaving their professions due to the strains of coping with the pandemic in their own lives, according to a new University of Utah Health study.

3 Apr 2021

Massive X-ray screening identifies several candidates for drugs against novel coronavirus

A team of researchers has identified several candidates for drugs against the coronavirus SARS-CoV-2 at DESY´s high-brilliance X-ray lightsource PETRA III.

3 Apr 2021

Material deprivation is driving Covid-19 disparities among ethnic minority groups

Deprivation among society at large is 'driving' Covid-19 disparities among minority ethnic groups - predominantly South Asian and Black African or Caribbean populations - and could be considered the main cause of disproportionate infection rates, hospitalization and deaths experienced by these populations, according to new analysis from the University of Leicester.

2 Apr 2021

Scientists identify nine potential new COVID-19 treatments

A team led by scientists in the Perelman School of Medicine at the University of Pennsylvania has identified nine potential new COVID-19 treatments, including three that are already approved by the Food and Drug Administration (FDA) for treating other diseases.

2 Apr 2021

Study shows decline in subarachnoid hemorrhage hospitalizations during COVID-19 pandemic

New research led by investigators from Boston Medical Center and Grady Memorial Hospital demonstrates the significant decline in hospitalizations for neurological emergencies during the COVID-19 pandemic.

2 Apr 2021

Study finds CD8+ T cell responses detect all major SARS-CoV-2 variants

There have been concerns that several SARS-CoV-2 variants have mutations that allow them to evade the immune system. A new study published in the Open Forum Infectious Diseases suggests otherwise. Led by Aaron AR Tobian of Johns Hopkins University School of Medicine, results showed that except for one from the B.1.351 variant, CD8+ T cells showed a broad response to all SARS-CoV-2 variants.

2 Apr 2021

First general selection criteria for lung transplantation in Covid-19 patients

In May 2020, a team led by thoracic surgeon Konrad Hoetzenecker of the Department of Surgery of MedUni Vienna and Vienna General Hospital performed a lung transplant on a 44-year-old patient who had been seriously ill with Covid-19, making her the first patient in Europe to receive a lung transplant for this indication.

2 Apr 2021

Muscle strength and mass may predict hospital stay duration in COVID-19 patients

Researchers found that COVID-19 patients with good muscle strength and higher muscle mass had a shorter stay in the hospital.

2 Apr 2021

Medicine News and Research

New software package employs deep-learning algorithms to analyze T-cell receptor sequencing data

Researchers Identify potent small molecule inhibitors against SARS-CoV-2

Study shows rates of prolonged visits for pediatric mental health ED visits increased over a decade

Genome analysis of more than 53,000 people offers valuable insights into dangerous diseases

Study paves way for effective monitoring of chemotherapeutic drug level in cancer patients

New approach to CAR T gene therapy yields efficient and longer-lasting response against HIV

Maternal exposure to pesticides may lead to central nervous system tumors during childhood

Treatment resistance in triple-negative breast cancers linked to softer tissue environment

Study uncovers novel mechanism in rare mutation associated with Alzheimer's

Video games may help improve surgical skills training for medical students

50-state analysis finds excess deaths from COVID-19 and other causes in the U.S.

Study: More than 60% of adult e-cigarette users in the U.S want to quit

Many health and academic professionals consider leaving their jobs after COVID-19, finds study

Massive X-ray screening identifies several candidates for drugs against novel coronavirus

Material deprivation is driving Covid-19 disparities among ethnic minority groups

Scientists identify nine potential new COVID-19 treatments

Study shows decline in subarachnoid hemorrhage hospitalizations during COVID-19 pandemic

Study finds CD8+ T cell responses detect all major SARS-CoV-2 variants

First general selection criteria for lung transplantation in Covid-19 patients

Muscle strength and mass may predict hospital stay duration in COVID-19 patients

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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