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New, promising approach combines metformin and SGLT2 inhibitors to treat diabetes

Various active substances in oral antidiabetic agents are frequently combined in the treatment of diabetes in order to achieve an effective reduction in the blood sugar. A new, very promising approach combines the substances metformin and SGLT2 inhibitors, the latter were just approved in 2012.

4 Aug 2014

5-LO enzyme plays important role in the survival of leukaemic AML stem cells

Despite improved therapy, only one out of every two adult patients survive acute myeloid leukaemia (AML). The mean survival time for this disease, which predominantly occurs in the elderly, is less than a year for patients over 65 years. It is assumed that leukaemic stem cells, which cannot be completely eliminated during treatment, are the origin of relapse.

4 Aug 2014

Neuralstem doses final patient with NSI-566 stem cells in Phase II trial

Neuralstem, Inc. announced that the final patient was treated in its Phase II trial using NSI-566 spinal cord-derived neural stem cells in the treatment of amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease).

4 Aug 2014

Metformin and SGLT2 inhibitors together reduce blood sugar levels

Metformin and SGLT2 inhibitors together reduce the blood sugar levels considerably more effectively than either drug alone.

4 Aug 2014

Leg ulcer treatment to be studied by sport scientists at Sheffield Hallam University

Sport and exercise scientists at Sheffield Hallam University have started a new study into the treatment of Chronic Venous Insufficiency (CVI), which affects patients' legs, often causing painful leg ulcers.

From Sheffield Hallam University 4 Aug 2014

New information on limitations and potential for development of transcranial ultrasound therapy

A recent study completed at the University of Eastern Finland provides new information on the limitations and potential new directions for the future development of transcranial ultrasound therapy.

4 Aug 2014

ACAAI offers practical solutions to improve asthma problem in older women

Women over the age of 65 face numerous barriers to good health: an increased risk for obesity, greater struggles against poverty and higher rates of asthma with worse health outcomes.

4 Aug 2014

Clinical trial to look for genetic information in cancer patients

Sanford Health is working to enroll approximately 50 adult patients whose cancer has progressed after the first line of treatment or who have rare cancers without standard treatment options in a clinical trial to look for genetic information that could help customize treatment options.

4 Aug 2014

FSMB takes effort to educate physicians on safe prescribing of opioid analgesics

The Federation of State Medical Boards (FSMB) announced today that the nation's state medical boards have kicked off a multi-state effort to educate health care professionals on the safe and responsible prescribing of extended-release (ER) and long-acting (LA) opioid analgesics for patients with chronic pain.

4 Aug 2014

New molecular test kit predicts survival outcomes in kidney cancer patients

Researchers and doctors at the Institute of Bioengineering and Nanotechnology (IBN), Singapore General Hospital (SGH) and National Cancer Centre Singapore (NCCS) have co-developed the first molecular test kit that can predict treatment and survival outcomes in kidney cancer patients. This breakthrough was recently reported in European Urology, the world's top urology journal.

4 Aug 2014

Research reveals that seizures linked to feelings of anxiety

New research by clinical psychologists from the UK and US has revealed psychogenic seizures which could be mistaken for epilepsy are linked to feelings of anxiety.

3 Aug 2014

New joint ESC/ESA Guidelines on non-cardiac surgery

The publication of the new joint ESC/ESA Guidelines on non-cardiac surgery: cardiovascular assessment and management introduces a number of recommendations in the field. Among other topics, the Guidelines include updated information on the use of clinical indices and biomarkers in risk assessment, and the use of novel anticoagulants, statins, aspirin and beta-blockers in risk mitigation.

1 Aug 2014

Blood test can predict recurrence of HPV-linked oral cancers

Research published yesterday indicates that recurrence of human papillomavirus (HPV)-induced cancers affecting the oropharynx (the area of the throat just behind the mouth) can be predicted by blood and saliva tests that screen for DNA fragments from HPV that have been shed by cancer cells.

1 Aug 2014

New supplement covers current knowledge and methods for management of AAICH

The Journal of Neurosurgery is pleased to announce today's publication of a supplement to the August issue entitled "Race Against the Clock: Overcoming Challenges in the Management of Anticoagulant-Associated Intracerebral Hemorrhage.

1 Aug 2014

TRIP13 protein encourages cancer cells to repair themselves

Imagine you're fighting for your life but no matter how hard you hit, your opponent won't go down. The same can be said of highly treatment-resistant cancers, such as head and neck cancer, where during radiation and chemotherapy some cancer cells repair themselves, survive and thrive.

1 Aug 2014

Blood and saliva tests help accurately predict recurrences of HPV associated oral cancers

Physicians at Johns Hopkins have developed blood and saliva tests that help accurately predict recurrences of HPV-linked oral cancers in a substantial number of patients.

1 Aug 2014

Combination therapy effective in treating drug-resistant malaria

Resistance to artemisinin, the main drug to treat malaria, is now widespread throughout Southeast Asia, among the Plasmodium falciparum (P. falciparum) parasites that cause the disease and is likely caused by a genetic mutation in the parasites.

31 Jul 2014

Findings underscore the importance of prenatal health care, postnatal breastfeeding

Young adults who were breastfed for three months or more as babies have a significantly lower risk of chronic inflammation associated with cardiovascular and metabolic diseases, according to research from the Brown School at Washington University in St. Louis.

31 Jul 2014

No two single tumor cells in breast cancer patients have same genome

Just as no two people possess the same genetic makeup, a recent study has shown that no two single tumor cells in breast cancer patients have an identical genome.

31 Jul 2014

Statin therapy may speed up wound healing following cardiac surgery

Statin therapy may help to improve wound healing in patients following cardiac surgery and reduce overall recovery time, especially in patients who are prone to healing complications, according to a review article in the August 2014 issue of The Annals of Thoracic Surgery.

31 Jul 2014