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Gothenburg study shows epilepsy surgery is a low-risk procedure

A study at Sahlgrenska Academy, University of Gothenburg, has found that epilepsy surgery is a safe, effective and low-risk procedure. Nevertheless, few Swedes have the operation, and those who are interested may have to wait a long time for presurgical counseling.

27 Nov 2014

Researchers use EHRs to uncover hidden drug benefits

With research and development costs for many drugs reaching well into the billions, pharmaceutical companies want more than ever to determine whether their drugs already at market have any hidden therapeutic benefits that could warrant putting additional indications on the label and increase production.

27 Nov 2014

TET1 enzyme may be important target for cancer diagnostics, treatment

Mutations in the KRAS gene have long been known to cause cancer, and about one third of solid tumors have KRAS mutations or mutations in the KRAS pathway. KRAS promotes cancer formation not only by driving cell growth and division, but also by turning off protective tumor suppressor genes, which normally limit uncontrolled cell growth and cause damaged cells to self-destruct.

27 Nov 2014

Cimetidine drug could be one of many common over-the-counter medicines to treat cancer

A popular indigestion medication can increase survival in colorectal cancer, according to research published in ecancermedicalscience. But in fact, scientists have studied this for years - and a group of cancer advocates want to know why this research isn't more widely used.

27 Nov 2014

European scientists develop, test drug that could reduce harmful side-effects of 'binge drinking'

A drug that could reduce the harmful side-effects of 'binge drinking', especially by teenagers, has been successfully developed and tested by a team of European scientists, including the University of Huddersfield's Professor Mike Page and Dr Karl Hemming. There is also the potential for new ways to treat Alzheimer's and other neurological diseases that damage the brain.

27 Nov 2014

SLU researcher discovers way to block pain pathway

In research published in the medical journal Brain, Saint Louis University researcher Daniela Salvemini, Ph.D. and colleagues within SLU, the National Institutes of Health and other academic institutions have discovered a way to block a pain pathway in animal models of chronic neuropathic pain including pain caused by chemotherapeutic agents and bone cancer pain suggesting a promising new approach to pain relief.

27 Nov 2014

Interventional X-ray guidance device may reduce radiation exposure of liver cancer patients

Johns Hopkins researchers report that their test of an interventional X-ray guidance device approved by the U.S. Food and Drug Administration in 2013 has the potential to reduce the radiation exposure of patients undergoing intra-arterial therapy (IAT) for liver cancer.

27 Nov 2014

Researchers demonstrate efficacy of Bozepinib drug against cancerogenic stem cells

An Andalusian team of researchers led by the University of Granada has demonstrated the efficacy of a new drug against cancerogenic stem cells, which cause the onset and development of cancer, of relapse after chemotherapy and metastasis. This drug, called Bozepinib, has proved to be effective in tests with mice.

26 Nov 2014

Johns Hopkins geriatrician documents barriers to better care of older adults

In what is believed to be the first interview-style qualitative study of its kind among health care providers in the trenches, a team led by a Johns Hopkins geriatrician has further documented barriers to better care of older adults as they are transferred from hospital to rehabilitation center to home, and too often back again.

26 Nov 2014

Nepstar revenue increases 8.1% to RMB738.3 million (US$120.3million) in Q3 2014

China Nepstar Chain Drugstore Ltd., a leading retail drugstore chain in China based on the number of directly operated stores, today announced its unaudited financial results for the third quarter ended September 30, 2014.

26 Nov 2014

New NIH funding to help researchers develop drug delivery system to prevent HIV infection in women

The University of Texas Medical Branch is part of a collaboration led by the Oak Crest Institute of Science that received a $20 million grant from the National Institutes of Health to develop a novel intravaginal ring capable of delivering powerful antiretroviral drugs to prevent the spread of sexually transmitted HIV in women. The total award to UTMB is approximately $2.5 million.

26 Nov 2014

Experimental anti-cancer drugs PF-04691502 and PD-0325901 excel against colorectal cancer models

Genes make proteins and proteins tell your body's cells what to do: one talks to the next, which talks to the next, and to the next. Like a game of telephone, researchers call these "signaling pathways". Abnormalities in these signaling pathways can cause the growth and survival of cancer cells. Commonly, mutations or rearrangements of genes in the MAPK signaling pathway create cancer's fast growth, and alterations in the PI3K signaling pathway allow cancer cells to survive into virtual immortality.

26 Nov 2014

Janssen submits YONDELIS NDA for treatment of advanced soft tissue sarcoma

PharmaMar announces that Janssen Research & Development, LLC has submitted a New Drug Application (NDA) for YONDELIS (trabectedin) to the U.S. Food and Drug Administration for the treatment of patients with advanced soft tissue sarcoma (STS), including liposarcoma and leiomyosarcoma subtypes, who have received prior chemotherapy including an anthracycline.

26 Nov 2014

Isis Pharmaceuticals announces initiation of ISIS-SMN Rx Phase 3 study in children with SMA

Isis Pharmaceuticals, Inc. announced today the initiation of a pivotal Phase 3 study evaluating ISIS-SMNRx in approximately 120 non-ambulatory children with spinal muscular atrophy (SMA).

25 Nov 2014

Scientists identify potential weakness in cancer's ability to become resistant to treatment

Scientists at the University of Manchester have discovered a potential weakness in cancer's ability to return or become resistant to treatment, by targeting the 'fuel' part of stem cells which allows tumours to grow.

25 Nov 2014

Study: Selenium compounds appear to have beneficial effect on cancer

The immune system is designed to remove things not normally found in the body. Cells undergoing change, e.g. precursors of cancer cells, are therefore normally recognised and removed by the immune system. Unfortunately, the different cancer cells contain mechanisms that block the immune system's ability to recognise them, allowing them to freely continue cancer development.

25 Nov 2014

New Mayo Clinic study shows impact of long-term use of proton pump inhibitors

Before reaching for that daily antacid, you might consider what it's doing to the trillions of bugs living in your gut. A new Mayo Clinic study in the open access journal Microbiome shows that people who regularly take proton pump inhibitors (PPIs) have less diversity among their gut bacteria, putting them at increased risk for infections like clostridium difficile and pneumonia, in addition to vitamin deficiencies and bone fractures.

25 Nov 2014

Two researchers receive Naomi Berrie Award for Outstanding Research in Diabetes

Columbia University Medical Center has presented Andrew Hattersley, DM, and Mark McCarthy, MD, with the 16th Naomi Berrie Award for Outstanding Research in Diabetes, for their work on the genetics of the disease. Their research has contributed to the discovery of new forms of the disease, improvements in diagnostic methodology, and the development of more effective treatments.

25 Nov 2014

Rice University researchers model dynamic instability of microtubules

New computer models that show how microtubules age are the first to match experimental results and help explain the dynamic processes behind an essential component of every living cell, according to Rice University scientists.

25 Nov 2014

Study shows that abuse of anti-anxiety, sleep drugs becomes a growing issue among teens

The medical community may be inadvertently creating a new generation of illegal, recreational drug users by prescribing anti-anxiety or sleep medications to teenagers, say University of Michigan researchers.

25 Nov 2014

Drugs News and Research

Gothenburg study shows epilepsy surgery is a low-risk procedure

Researchers use EHRs to uncover hidden drug benefits

TET1 enzyme may be important target for cancer diagnostics, treatment

Cimetidine drug could be one of many common over-the-counter medicines to treat cancer

European scientists develop, test drug that could reduce harmful side-effects of 'binge drinking'

SLU researcher discovers way to block pain pathway

Interventional X-ray guidance device may reduce radiation exposure of liver cancer patients

Researchers demonstrate efficacy of Bozepinib drug against cancerogenic stem cells

Johns Hopkins geriatrician documents barriers to better care of older adults

Nepstar revenue increases 8.1% to RMB738.3 million (US$120.3million) in Q3 2014

New NIH funding to help researchers develop drug delivery system to prevent HIV infection in women

Experimental anti-cancer drugs PF-04691502 and PD-0325901 excel against colorectal cancer models

Janssen submits YONDELIS NDA for treatment of advanced soft tissue sarcoma

Isis Pharmaceuticals announces initiation of ISIS-SMN Rx Phase 3 study in children with SMA

Scientists identify potential weakness in cancer's ability to become resistant to treatment

Study: Selenium compounds appear to have beneficial effect on cancer

New Mayo Clinic study shows impact of long-term use of proton pump inhibitors

Two researchers receive Naomi Berrie Award for Outstanding Research in Diabetes

Rice University researchers model dynamic instability of microtubules

Study shows that abuse of anti-anxiety, sleep drugs becomes a growing issue among teens

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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