Surgery News and Research

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Exparel (DepoBupivacaine) shows promise in hernia repair

A Phase II trial of a single intraoperative administration of Exparel (DepoBupivacaine) resulted in significantly reduced pain with activity in the first 8 to 24 hours following surgery, when pain is generally greatest, compared to conventional treatment.

14 Dec 2008

Zometa (zoledronic acid) shown to enhance chemotherapy in reducing breast tumor size

New data released demonstrates that the addition of Zometa (zoledronic acid) injection to standard chemotherapy before breast cancer surgery reduces the size of breast tumors more effectively than chemotherapy alone in women with early-stage disease.

14 Dec 2008

Postmenopausal patients being considered for tamoxifen therapy should be tested for CYP2D6 gene deficiency

Findings from a new study have prompted Mayo Clinic researchers to recommend CYP2D6 gene testing for postmenopausal women about to begin tamoxifen therapy.

14 Dec 2008

Femara shows reduced risk of death versus tamoxifen after breast cancer surgery

Femara showed reduced risk of death by 13% (P=0.08) versus tamoxifen, despite inclusion of patients who had switched over from tamoxifen to Femara during the study period, following the study's unblinding.

14 Dec 2008

Early-stage breast cancer patients with HER2 positive tumors at increased risk of recurrence

Early-stage breast cancer patients with HER2 positive tumors one centimeter or smaller are at significant risk of recurrence of their disease, compared to those with early-stage disease who do not express the aggressive protein, according to a study led by researchers at The University of Texas M. D. Anderson Cancer Center.

14 Dec 2008

Study examines how women's magazines portray cosmetic surgery

While the emotional health implications of cosmetic surgery are still up for scientific debate, articles in women's magazines such as The Oprah Magazine and Cosmopolitan portray cosmetic surgery as a physically risky, but overall worthwhile option for enhancing physical appearance and emotional health, a UBC study has found.

12 Dec 2008

Trial looks at new treatment for solid cancer tumors and non-Hodgkin's lymphoma

Researchers at The Cancer Institute of New Jersey (CINJ) have opened a clinical trial, which aims to evaluate a new treatment for solid cancer tumors and non-Hodgkin's lymphoma (NHL) in combination with a chemotherapy agent called cyclophosphamide.

12 Dec 2008

AEterna Zentari completes recruitment for phase 3 trial with Cetrorelix in benign prostatic hyperplasia

AEterna Zentaris Inc. has reported it has reached its goal of recruiting 500 patients for the safety study of the Phase 3 program in benign prostatic hyperplasia (BPH) with its flagship product candidate, cetrorelix, a novel investigational luteinizing hormone-releasing hormone (LHRH) antagonist.

11 Dec 2008

Magnets in toys pose serious health risks

While the danger of magnets for children is increasingly recognized, they don't receive treatment for swallowing them as quickly as needed, and parents don't receive sufficient warning on toys, according to a new study.

10 Dec 2008

Many mouth cancers found too late

Worldwide, more than 500,000 new cases of cancer of the mouth are diagnosed each year.

10 Dec 2008

New spinal deformity classification system

A University of Cincinnati (UC) neurosurgeon who has spent his career helping people with severe spine problems stand up straight has spearheaded the creation of a new spinal deformity classification system.

10 Dec 2008

3D imaging technology improves spinal surgery outcome

Using a three-dimensional (3D) image-guided system to help place screws in the spines of patients results in safe and accurate surgery with a decrease in the number of misplaced screws, and subsequent injuries, seen in more traditional operations, say neurosurgeons at Mayo Clinic in Florida.

10 Dec 2008

New titanium dental implant

Manhattan Scientifics has announced that its affiliated manufacturing partner in Albuquerque, N.M. has received Food and Drug Administration 510(k) clearance to market Manhattan Scientifics' super strong titanium metal dental implants.

10 Dec 2008

Axial Biotech launches DNA-based test for adolescent idiopathic scoliosis

Axial Biotech, Inc. has announced the commercial launch of a new DNA-based test that indicates the likelihood of progression to a severe curve for children diagnosed with Adolescent Idiopathic Scoliosis (AIS).

10 Dec 2008

AcelRx Pharmaceuticals reports positive results in trial of sublingual Sufentanil NanoTabs in treating post-op pain

AcelRx Pharmaceuticals, Inc. today announced positive results from a Phase 2 clinical study evaluating the safety and efficacy of its lead product candidate, ARX-01, for the treatment of moderate-to-severe inpatient acute pain following knee replacement surgery.

10 Dec 2008

New mobile health van will tackle ear problems amongst children in remote Indigenous communities

An innovative new medical program in Queensland will use the latest technology to help treat children living in remote Indigenous communities.

9 Dec 2008

Study identifies characteristics of hospitals with low rates of surgical site infections

New research published in the December issue of the Journal of the American College of Surgeons (JACS) suggests that surgical procedures that are shorter in duration and the use of fewer blood transfusions characterize hospitals that have a lower incidence of surgical site infections (SSI).

8 Dec 2008

Levels of insulin-related proteins indicate risk of death in some colorectal cancer patients

A pair of proteins may help explain why people with surgically removed colorectal cancer and who are overweight, physically inactive, and follow a Western-pattern diet may have an increased risk of dying of the disease or other causes, Dana-Farber Cancer Institute scientists report in a new study.

8 Dec 2008

Best obesity treatment

Severely obese patients who have lost significant amounts of weight by changing their diet and exercise habits may be as successful in keeping the weight off long-term as those individuals who lost weight after bariatric surgery, according to a new study published online by the International Journal of Obesity.

8 Dec 2008

Cytori reports benefit of adipose-derived regenerative cells in spinal disc model

Cytori Therapeutics, Inc. reported preclinical study results, which demonstrate the potential benefit of adipose-derived stem and regenerative cells (ADRCs) for the treatment of damaged intervertebral discs, evidenced by significantly increased disc tissue density and disc-specific extracellular matrix components at 12-months post treatment in a large animal model.

8 Dec 2008

Surgery News and Research

Exparel (DepoBupivacaine) shows promise in hernia repair

Zometa (zoledronic acid) shown to enhance chemotherapy in reducing breast tumor size

Postmenopausal patients being considered for tamoxifen therapy should be tested for CYP2D6 gene deficiency

Femara shows reduced risk of death versus tamoxifen after breast cancer surgery

Early-stage breast cancer patients with HER2 positive tumors at increased risk of recurrence

Study examines how women's magazines portray cosmetic surgery

Trial looks at new treatment for solid cancer tumors and non-Hodgkin's lymphoma

AEterna Zentari completes recruitment for phase 3 trial with Cetrorelix in benign prostatic hyperplasia

Magnets in toys pose serious health risks

Many mouth cancers found too late

New spinal deformity classification system

3D imaging technology improves spinal surgery outcome

New titanium dental implant

Axial Biotech launches DNA-based test for adolescent idiopathic scoliosis

AcelRx Pharmaceuticals reports positive results in trial of sublingual Sufentanil NanoTabs in treating post-op pain

New mobile health van will tackle ear problems amongst children in remote Indigenous communities

Study identifies characteristics of hospitals with low rates of surgical site infections

Levels of insulin-related proteins indicate risk of death in some colorectal cancer patients

Best obesity treatment

Cytori reports benefit of adipose-derived regenerative cells in spinal disc model

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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