Clinical Trial News and Research

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Ketogenic diet shows promise in curbing cravings in alcohol use disorder patients

Study found that a ketogenic diet (KD) significantly increased serum beta-hydroxybutyrate levels, suggesting nutritional ketosis, and showed a trend towards reducing self-reported alcohol craving and a neurobiological craving signature (NCS) for alcohol in patients with alcohol use disorder (AUD), indicating its potential to modulate alcohol craving.

14 Feb 2024

Enhancing survival in advanced pancreatic cancer with ablative MR-guided radiation therapy

A study co-led by researchers at Miami Cancer Institute, part of Baptist Health South Florida, found that ablative stereotactic magnetic resonance (MR)-guided adaptive radiation therapy may improve local control (LC) and overall survival (OS) in patients with borderline resectable (BRPC) and locally advanced pancreas cancer (LAPC).

14 Feb 2024

Researchers develop enhanced immunotherapy for multiple myeloma treatment

Immunotherapy is already improving treatment options for many cancer types, but research groups keep exploring ways to boost the body's immune response against the tumor.

14 Feb 2024

Identifying immunotherapy resistance in liver cancer linked to steatotic disease

A research team of Canadian and French scientists, led by INRS professor Maya Saleh, has been investigating immunotherapy resistance in certain patients with hepatocellular carcinoma (HCC) associated with steatotic liver disease.

14 Feb 2024

Novel three-drug combo shows promise in advanced HER2-negative breast cancer treatment

A novel three-drug combination achieved notable responses in patients with advanced HER2-negative breast cancer, according to new research directed by investigators from the Johns Hopkins Kimmel Cancer Center.

14 Feb 2024

Routine change of gloves and instruments is cost-effective and reduces surgical site infections

Surgeons who routinely change surgical gloves and instruments are incurring similar costs to those using the same equipment, a new study has found.

14 Feb 2024

Revvity Signals Software unveils Signals Clinical solution to accelerate critical clinical trial insights and data-driven decisions

Today, Revvity, Inc. announced that its software and informatics division, Revvity Signals, is unveiling the Signals Clinical™ solution, a software-as-a-service (SaaS), end-to-end clinical data science platform designed to centralize all clinical trial data, providing fast, actionable insights for quicker clinical decisions and accelerated market delivery of therapeutics.

From Revvity 14 Feb 2024

Mediterranean and vegetarian diets boost heart health by improving novel CVD markers

Study reveals that both lacto-ovo vegetarian and Mediterranean diets positively impact apolipoprotein levels and cardiovascular disease risk factors, with Mediterranean diet showing a more substantial effect on apolipoprotein levels, particularly in women and older individuals with fewer CVD risk factors.

13 Feb 2024

Novel protocol developed to rapidly diagnose eye stroke and expedite care

Ophthalmologists at New York Eye and Ear Infirmary of Mount Sinai (NYEE) have created a novel protocol to rapidly diagnose eye stroke and expedite care to prevent irreversible vision loss.

13 Feb 2024

Therapist-guided digital therapy reduces distress in people with long-term physical health conditions

A therapist-guided digital cognitive behavioural therapy reduced distress in 89 per cent of participants living with long-term physical health conditions, a new King's College London study finds.

13 Feb 2024

Pre-pandemic exercise tied to lower odds of COVID-19 infection and hospitalization

A cohort study of older adults found that those who followed recommended exercise guidelines before the pandemic had significantly lower odds of being infected or hospitalized from COVID-19 than those who did not follow guidelines.

13 Feb 2024

Daily aspirin linked to higher mortality in older adults, study finds

A study from the ASPREE clinical trial found that daily aspirin intake in adults over 70 did not increase disability-free survival and was associated with higher all-cause mortality, primarily due to cancer-related deaths.

12 Feb 2024

Promising new CMV vaccine shows stronger immune response

An experimental mRNA vaccine against human cytomegalovirus (CMV), a common virus that can infect babies during pregnancy, elicited some of the most promising immune responses to date of any CMV vaccine candidate, according to a study by Weill Cornell Medicine investigators.

12 Feb 2024

Study uncovers missing piece in the complex nerve-network needed for left-right turns

Have you ever wondered what happens in the brain when we move to the right or left? Most people don't; they just do it without thinking about it. But this simple movement is actually controlled by a complex process.

12 Feb 2024

Blocking artery plus surgery offers hope for reducing reoperations in brain hematoma patients

Injection of a substance to block an artery feeding the dura (protective sack around the brain) along with surgery to remove pooled blood reduced the risk that patients will require repeat surgery compared to surgical drainage alone, according to preliminary late-breaking science presented today at the American Stroke Association's International Stroke Conference 2024.

9 Feb 2024

Nutritional epigenetics education reduces ultra-processed food intake in parents of children with autism and ADHD

In a recent publication released by PubMed, American scientists led by Dr. Dufault at the Food Ingredient and Health Research Institute, reported the results of a clinical trial in which parents who received nutritional epigenetics education significantly reduced their consumption of ultra-processed foods while increasing their intake of whole and/or organic foods.

9 Feb 2024

Scientists develop safer CAR T-cell strategy for treating lymphomas

In the treatment of aggressive lymphomas and blood cancer (leukaemia), so-called chimeric antigen receptor T cells (CAR T cells) are increasingly being used.

9 Feb 2024

Selective androgen receptor modulator has anti-tumor effects in ER-positive breast cancer patients

A research paper published today (8 February 2024) in The Lancet Oncology demonstrates that the drug enobosarm, a selective androgen receptor modulator which stimulates the male sex hormone receptor has anti-tumour effects in estrogen receptor positive breast cancer patients.

8 Feb 2024

Stroke patients see lower death rates with AI-guided treatment

Ischemic stroke survivors who received care recommendations from an artificial intelligence (AI)-based system had fewer recurrent strokes, heart attacks or vascular death within three months, compared to people whose stroke treatment was not guided by AI tools, according to preliminary late-breaking science presented today at the American Stroke Association's International Stroke Conference 2024.

8 Feb 2024

Hope for relapsed myeloma: Preclinical and clinical evidence for ruxolitinib's efficacy

A new research perspective was published in Oncotarget's Volume 15 on February 5, 2024, entitled, "Preclinical and clinical evaluation of the Janus Kinase inhibitor ruxolitinib in multiple myeloma."

8 Feb 2024

Clinical Trial News and Research

Ketogenic diet shows promise in curbing cravings in alcohol use disorder patients

Enhancing survival in advanced pancreatic cancer with ablative MR-guided radiation therapy

Researchers develop enhanced immunotherapy for multiple myeloma treatment

Identifying immunotherapy resistance in liver cancer linked to steatotic disease

Novel three-drug combo shows promise in advanced HER2-negative breast cancer treatment

Routine change of gloves and instruments is cost-effective and reduces surgical site infections

Revvity Signals Software unveils Signals Clinical solution to accelerate critical clinical trial insights and data-driven decisions

Mediterranean and vegetarian diets boost heart health by improving novel CVD markers

Novel protocol developed to rapidly diagnose eye stroke and expedite care

Therapist-guided digital therapy reduces distress in people with long-term physical health conditions

Pre-pandemic exercise tied to lower odds of COVID-19 infection and hospitalization

Daily aspirin linked to higher mortality in older adults, study finds

Promising new CMV vaccine shows stronger immune response

Study uncovers missing piece in the complex nerve-network needed for left-right turns

Blocking artery plus surgery offers hope for reducing reoperations in brain hematoma patients

Nutritional epigenetics education reduces ultra-processed food intake in parents of children with autism and ADHD

Scientists develop safer CAR T-cell strategy for treating lymphomas

Selective androgen receptor modulator has anti-tumor effects in ER-positive breast cancer patients

Stroke patients see lower death rates with AI-guided treatment

Hope for relapsed myeloma: Preclinical and clinical evidence for ruxolitinib's efficacy

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