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Phase I/II LIBRETTO-001 trial: RET inhibitor achieves durable objective responses across multiple tumors

The highly selective RET inhibitor selpercatinib was well-tolerated and achieved durable objective responses across multiple tumor types in the Phase I/II LIBRETTO-001 trial, according to researchers from The University of Texas MD Anderson Cancer Center.

12 Sep 2022

Study underscores the economic, mental health impacts of COVID-19 on people hit by climate disasters

When the Children's Environmental Health Initiative (CEHI) launched the Texas Flood Registry in April 2018, the goal was to develop a needs assessment focusing on health and housing impacts of the greater Houston area, which was still recovering less than one year after Hurricane Harvey's devastating landfall.

12 Sep 2022

Review of COVID-19 in children before and after SARS-CoV-2 Delta and Omicron variant emergence

Researchers provided a summary of SARS-CoV-2 infections among children pre- and post-SARS-CoV-2 Delta and Omicron variants of concern (VOCs) emergence.

12 Sep 2022

The long-term clinical status of pediatric patients after testing positive for COVID-19

A recent study found that the most common long COVID symptoms in the pediatric population showed a higher prevalence among patients in the age range of 6-17 years and were identical to those reported in adults.

12 Sep 2022

Pre-existing psychological distress increases risk of long-COVID

In a recent study published in the Journal of American Medical Association (JAMA) Psychiatry, researchers investigated the association of psychological distress before coronavirus disease 2019 (COVID-19) with the risk of post-acute sequelae of COVID-19 (PASC).

12 Sep 2022

Many neurocognitive benefits conferred on children born to mothers who eat fish

In a recent study published in the Neurotoxicology journal, researchers explored the benefits of fish consumption in pregnant women.

12 Sep 2022

Pollutant particles in the air trigger lung cancer in non-smokers

A new mechanism has been identified through which very small pollutant particles in the air may trigger lung cancer in people who have never smoked, paving the way to new prevention approaches and development of therapies, according to late-breaking data [to be] reported at the ESMO Congress 2022 by scientists of the Francis Crick Institute and University College London, funded by Cancer Research UK. The particles, which are typically found in vehicle exhaust and smoke from fossil fuels, are associated with non-small cell lung cancer (NSCLC) risk, accounting for over 250,000 lung cancer deaths globally per year.

12 Sep 2022

A direct side-by-side comparison of all available COVID-19 vaccines

In a recent study posted to the medRxiv* preprint server, researchers assessed immune responses to homologous and heterologous coronavirus disease 2019 (COVID-19) vaccine combinations among Córdoba, Spain residents.

11 Sep 2022

Individual COVID-19 infections include multiple variants of the SARS-CoV-2 virus, research shows

Researchers at Case Western Reserve University found wide genetic variation in SARS-CoV-2 viruses among 360 patients whose viral infections were genetically sequenced, showing that all individual infections include multiple variants of the virus.

9 Sep 2022

Factors influencing patient’s perception during COVID-19 recovery

A team of researchers characterized individual-level illness perception, both cognitive and emotional, following COVID-19.

9 Sep 2022

The evolution of humoral immune responses over the course of Epstein-Barr virus infection

Researchers explored probable humoral immune mechanisms related to EBV curtailment, besides neutralization, by a systematic emphasis on antibody fragment crystallizable-functional activities over the course of EBV infections.

9 Sep 2022

Comprehensive genetic architecture atlas compiled for mutant RAS genes in cancers

Researchers at the Johns Hopkins Kimmel Cancer Center, three other cancer centers and the Johns Hopkins Bloomberg School of Public Health compiled a comprehensive genetic architecture atlas for mutant RAS genes in human cancers.

8 Sep 2022

How does previous SARS-CoV-2 infection impact the B cell receptor repertoire in response to vaccination?

Researchers evaluated immune responses by B lymphocytes to Pfizer’s severe acute respiratory syndrome coronavirus 2 mRNA vaccine.

8 Sep 2022

How can Legionella pneumophila transmit through the hot water plumbing of residences and office buildings?

Researchers investigate the transmission of the causative agent of legionellosis, Legionella pneumophila, through hot water plumbing systems in commercial and residential buildings.

8 Sep 2022

York University secures CAD7.25 million grant to help tackle emerging or re-emerging infectious diseases

At a time when the risk of emerging or re-emerging infectious diseases (ERIDs) is increasing, an international team led by York University successfully competed to receive a CAD7.25 million grant from the International Development Research Centre (IDRC) to help tackle the issue.

7 Sep 2022

How does SARS-CoV-2 affect the male genitourinary system?

In a recent paper published in the American Journal of Clinical and Experimental Urology, researchers reviewed existing data on the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections on the male genitourinary (GU) tract.

7 Sep 2022

Study highlights the importance of having a dedicated women-specific heart center

Cardiac conditions in women are underdiagnosed, undertreated, and under-researched compared to men. In an important prospective study in the Canadian Journal of Cardiology, published by Elsevier, investigators report that attending a multidisciplinary dedicated women's heart center can increase the likelihood of an accurate diagnosis and significantly improve clinical and psychological outcomes of women reporting chest pain due to insufficient heart-muscle blood flow (myocardial ischemia) but not diagnosed with obstructive coronary artery disease.

7 Sep 2022

Frequency News and Research

Phase I/II LIBRETTO-001 trial: RET inhibitor achieves durable objective responses across multiple tumors

Study underscores the economic, mental health impacts of COVID-19 on people hit by climate disasters

Review of COVID-19 in children before and after SARS-CoV-2 Delta and Omicron variant emergence

The long-term clinical status of pediatric patients after testing positive for COVID-19

Pre-existing psychological distress increases risk of long-COVID

Many neurocognitive benefits conferred on children born to mothers who eat fish

Pollutant particles in the air trigger lung cancer in non-smokers

A direct side-by-side comparison of all available COVID-19 vaccines

Individual COVID-19 infections include multiple variants of the SARS-CoV-2 virus, research shows

Factors influencing patient’s perception during COVID-19 recovery

The evolution of humoral immune responses over the course of Epstein-Barr virus infection

Comprehensive genetic architecture atlas compiled for mutant RAS genes in cancers

How does previous SARS-CoV-2 infection impact the B cell receptor repertoire in response to vaccination?

How can Legionella pneumophila transmit through the hot water plumbing of residences and office buildings?

York University secures CAD7.25 million grant to help tackle emerging or re-emerging infectious diseases

How does SARS-CoV-2 affect the male genitourinary system?

Study highlights the importance of having a dedicated women-specific heart center

Researchers assess how the pandemic may have altered American's' decisions to change residences

The existing molecular variance levels in haplotypes of the interferon-alpha-beta receptor gene in Orthopoxviruses

Ultra-processed food may increase colorectal cancer risk in men

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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