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Researchers discover dose threshold that improves delivery of cancer-fighting drugs into a tumor

University of Toronto Engineering researchers have discovered a dose threshold that greatly increases the delivery of cancer-fighting drugs into a tumor.

11 Aug 2020

Oxytocin can aid in the control and prevention of osteoporosis

Oxytocin, produced by the hypothalamus and sometimes known as the "love hormone" for its involvement in pair bonding and orgasm, can be a strong ally in the control and prevention of osteoporosis, according to a study by scientists at São Paulo State University in Brazil.

10 Aug 2020

Study suggests novel strategy to slow down evolution of antibiotic resistance

The rise of antibiotic resistance in many pathogens has been driven by the spread of a small number of strains, suggesting that some bacteria may be genetically pre-disposed to evolving resistance.

10 Aug 2020

Scientists find new way of identifying and targeting hidden HIV viral reservoirs during ART therapy

Scientists at The Wistar Institute may have discovered a new way of identifying and targeting hidden HIV viral reservoirs during treatment with antiretroviral therapy (ART).

7 Aug 2020

Method provides new insight into brain cells that maintain body's master circadian clock.

UT Southwestern scientists have developed a genetically engineered mouse and imaging system that lets them visualize fluctuations in the circadian clocks of cell types in mice.

7 Aug 2020

Nanomedicine-based strategy enhances anti-PD1 therapy to eradicate PTEN-negative GBM

A nanomedicine-based strategy for chemo-immunotherapy (CIT) of glioblastoma (GBM), which has the worst prognosis among brain tumors, was successfully developed.

7 Aug 2020

Study: Drinking honeysuckle decoction accelerates the negative conversion of COVID-19 patients

In a new study in Cell Discovery, Chen-Yu Zhang's group at Nanjing University and two other groups from Wuhan Institute of Virology and the Second Hospital of Nanjing present a novel finding that absorbed miRNA MIR2911 in honeysuckle decoction (HD) can directly target SARS-CoV-2 genes and inhibit viral replication. Drinking of HD accelerate the negative conversion of COVID-19 patients.

7 Aug 2020

HDAC6 inhibitors increase efficacy of immunotherapy in triple-negative breast cancer

Genetic modifier HDAC6 was found to control tumor growth and halt metastasis in triple-negative breast cancer in vivo, according to a new study published in the top-tier journal Cancer Research by investigators at the George Washington University (GW) Cancer Center.

6 Aug 2020

Researchers investigate why irregular heartbeats occur after stem cell transplantation

Stem cells are heavily studied around the world with the hope to revive damaged body parts unable to regenerate itself. Injured heart muscles are one of these areas which remain impaired in adults who have experienced heart attacks.

5 Aug 2020

Regeneron antibody cocktail shows promise as potential COVID-19 treatment

Researchers in the U.S. have shown both preventive and treatment effects of an antibody cocktail in animal models of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) - the agent that causes coronavirus disease 2019 (COVID-19).

4 Aug 2020

Researchers develop scalable strategy to find novel molecular glue degraders

Despite enormous efforts to advance traditional pharmacology approaches, more than three quarters of all human proteins remain beyond the reach of therapeutic development.

4 Aug 2020

Scientists develop human lung organoids to study SARS-CoV-2 infection

Now, a new study published on the preprint server bioRxiv in July 2020 reports the development of a human distal lung culture system that can be functionally tested. This will help not only to understand how this infection produces disease but also to test the proliferative capacity of the stem cells in this part of the body.

30 Jul 2020

Antimalarial drug shows in vitro activity against SARS-CoV-2 and flu viruses

Now, a new study published in the preprint server bioRxiv in July 2020 reports on the antiviral activity of two drugs found in an antimalarial drug currently in phase II trials in South Korea, called Pyramax.

30 Jul 2020

Study reveals multiple characteristics of HIV-1-producing cells in vivo

For eradication of HIV-1 infection, it is important to elucidate the detailed features and heterogeneity of HIV-1-infected cells in vivo.

29 Jul 2020

A new cell-based gene therapy approach to better treat patients with hemophilia A

In a new study from the Wake Forest Institute for Regenerative Medicine researchers have developed an optimized cellular platform for delivering Factor 8 to better treat patients with hemophilia A.

28 Jul 2020

Novel label-free imaging method can differentiate active T cells from those off duty

T cells are the immune soldiers at the frontlines of the battle with infiltrating pathogens that seek to cause disease. A new study published in Nature Biomedical Engineering describes a novel label-free imaging technique that can differentiate active T cells from those off duty.

27 Jul 2020

in vivo News and Research

Researchers discover dose threshold that improves delivery of cancer-fighting drugs into a tumor

Oxytocin can aid in the control and prevention of osteoporosis

Study suggests novel strategy to slow down evolution of antibiotic resistance

Scientists find new way of identifying and targeting hidden HIV viral reservoirs during ART therapy

Method provides new insight into brain cells that maintain body's master circadian clock.

Nanomedicine-based strategy enhances anti-PD1 therapy to eradicate PTEN-negative GBM

Study: Drinking honeysuckle decoction accelerates the negative conversion of COVID-19 patients

HDAC6 inhibitors increase efficacy of immunotherapy in triple-negative breast cancer

Researchers investigate why irregular heartbeats occur after stem cell transplantation

Regeneron antibody cocktail shows promise as potential COVID-19 treatment

Researchers develop scalable strategy to find novel molecular glue degraders

Scientists develop human lung organoids to study SARS-CoV-2 infection

Antimalarial drug shows in vitro activity against SARS-CoV-2 and flu viruses

Study reveals multiple characteristics of HIV-1-producing cells in vivo

A new cell-based gene therapy approach to better treat patients with hemophilia A

Novel label-free imaging method can differentiate active T cells from those off duty

Study reveals manifold applications of cytokine transcriptional response modules in COVID-19

Brazilian researchers produce an optical fiber made of agar

An important SARS-CoV-2 enzyme is responsible for low in vivo antiviral efficacy of hydroxychloroquine

Gene signature explains why 18F-FDG imaging performs better for PSMA-suppressed prostate cancer patients

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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