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Researchers receive $8 million NCI grant to study effects of PDT in patients with mesothelioma

Researchers at the Perelman School of Medicine at the University of Pennsylvania in collaboration with the Roswell Park Cancer Institute have received an $8 million grant from the National Cancer Institute to study the effects of photodynamic light therapy (PDT) in patients with malignant pleural mesothelioma, a rare, aggressive and deadly cancer that most often manifests itself in the lining of the lungs and is caused almost exclusively by exposure to asbestos.

10 Jul 2014

Regeneron, Sanofi report positive results from dupilumab Phase 2b study in moderate-to-severe AD

Regeneron Pharmaceuticals, Inc. and Sanofi today announced positive results from a Phase 2b dose-ranging study of dupilumab, an investigational therapy, in adult patients with moderate-to-severe atopic dermatitis (AD), a serious, chronic form of eczema.

10 Jul 2014

Quantel Medical receives FDA clearance for Optimis Fusion integrated laser platform

Quantel Medical today announced FDA 510(k) clearance for its Optimis Fusion integrated laser platform. The Optimis Fusion system combines advanced selective laser trabeculoplasty (SLT) photoregeneration therapy and traditional YAG photodisruption treatments to offer ophthalmologists a versatile armamentarium for treating both cataract and glaucoma in an efficient combination platform.

10 Jul 2014

Integrated therapies can reduce depression by half among people with low vision due to AMD

The first clinical trial to examine integrated low vision and mental health treatment has shown that the approach can reduce the incidence of depression by half among people with low vision due to age-related macular degeneration (AMD).

9 Jul 2014

Lung cancer and melanoma funders form first-ever research collaboration

LUNGevity Foundation today announced a partnership with the Lung Cancer Research Foundation and Melanoma Research Alliance to co-fund new innovative research on PD-1 inhibitor treatment options for both non-small cell lung cancer (NSCLC) and metastatic melanoma (MM) patients with brain metastases.

9 Jul 2014

New therapeutic targets release mechanisms in reactive astrocytes for treatment of Alzheimer's disease

Alzheimer's disease, which is the most common cause of dementia, is fatal and currently, there is no cure. In Alzheimer's disease, brain cells are damaged and destroyed, leading to devastating memory loss.

9 Jul 2014

Drowning remains leading cause of death in children with autism

Many families beat the summer heat with trips to swimming pools, beaches, and water parks; but water safety concerns are particularly heightened for families of children with autism, said Varleisha Gibbs, OTD, OTR/L, occupational therapy professor at University of the Sciences in Philadelphia.

9 Jul 2014

New approach can reduce depression in patients with AMD-related low vision

Depression is a common risk for people who have lost their vision from age-related macular degeneration (AMD), but a new study shows that a type of rehabilitation therapy can cut this risk in half. The study was funded by the National Eye Institute (NEI), part of the National Institutes of Health.

9 Jul 2014

Pain control in osteoarthritis patients

Osteoarthritis (OA) is one of the most common causes of disability, and inadequate pain control can lead to joint stiffness that may impair mobility for patients.

9 Jul 2014

New gene therapy may be effective for fighting fungal infections in cancer patients

Sleeping Beauty and fungal infections - not two items one would normally associate together, but for immunocompromised cancer patients they may prove to be a helpful combination.

9 Jul 2014

Over 650 000 children develop tuberculosis every year in the 22 HBCs according to new estimates

New estimates indicate that over 650 000 children develop tuberculosis (TB) every year in the 22 countries with a high burden of the disease (HBCs)*—almost 25% higher than the total number of new cases worldwide estimated by WHO in 2012 (530 000)**. The research, published in The Lancet Global Health, also suggests that about 15 million children are exposed to TB every year, and roughly 53 million are living with latent TB infection, which can progress to infectious active TB at any time.

9 Jul 2014

UCLA project receives $15M to restore lost memory functions in brain-injured people

The UCLA Program in Memory Restoration has been awarded up to $15 million by the Defense Advanced Research Projects Agency (DARPA) for a four -year project aiming to help brain-injured people restore lost memory functions.

9 Jul 2014

Research finding offers potential therapeutic avenues for glioblastoma

Invading glioblastoma cells may hijack cerebral blood vessels during early stages of disease progression and damage the brain's protective barrier, a study in mice indicates. This finding could ultimately lead to new ways to bring about the death of the tumor, as therapies may be able to reach these deadly cells at an earlier time point than was previously thought possible.

9 Jul 2014

Study gives parents, doctors new options to treat children with eczema

The number of children with atopic dermatitis, often referred to as eczema, is on the rise. Some estimate that one in five children in the U.S. now suffers from the painful, itchy skin condition. In an effort to control their symptoms, many children are prescribed powerful medications like immunosuppressants or topical steroids.

9 Jul 2014

Combining NRT with varenicline improves smoking abstinence

Combining the smoking cessation medication varenicline with nicotine replacement therapy was more effective than varenicline alone at achieving tobacco abstinence at 6 months, according to a study in the July 9 issue of JAMA.

8 Jul 2014

Fabry disease awareness: an interview with Dr. Hartmann Wellhoefer, Head of Medical Affairs, Rare Disease, Shire

Lysosomes are subcellular organelles that are present in most cells, with the major exception of red blood cells.

8 Jul 2014

Oncolytics completes patient enrollment in phase II metastatic pancreatic cancer study

Oncolytics Biotech Inc. today announced completion of patient enrollment in a two-arm randomized phase II study of carboplatin, paclitaxel plus REOLYSIN versus carboplatin and paclitaxel alone in the first line treatment of patients with recurrent or metastatic pancreatic cancer (OSU-10045).

8 Jul 2014

Novel cancer immunotherapy for dogs could benefit humans as well

As in humans, cancers in dogs have complex causes. The interaction of the environment, food, and genetic disposition are the most well known factors. Today nearly all methods of human medicine are basically available for dogs with cancer, but this was not true of cancer immunotherapy so far.

8 Jul 2014

Hypertension does not respond to therapy due to inadequate diagnosis

High blood pressure—also known as hypertension—is widespread, but treatment often fails. One in five people with hypertension does not respond to therapy. This is frequently due to inadequate diagnosis, as Franz Weber and Manfred Anlauf point out in the current issue of Deutsches Ärzteblatt International.

8 Jul 2014

First report of spinal cord mass arising from spinal cord cell transplantation

A spinal mass was identified in a young woman with complete spinal cord injury 8 years after she had undergone implantation of olfactory mucosal cells in the hopes of regaining sensory and motor function.

8 Jul 2014

Therapy News and Research

Researchers receive $8 million NCI grant to study effects of PDT in patients with mesothelioma

Regeneron, Sanofi report positive results from dupilumab Phase 2b study in moderate-to-severe AD

Quantel Medical receives FDA clearance for Optimis Fusion integrated laser platform

Integrated therapies can reduce depression by half among people with low vision due to AMD

Lung cancer and melanoma funders form first-ever research collaboration

New therapeutic targets release mechanisms in reactive astrocytes for treatment of Alzheimer's disease

Drowning remains leading cause of death in children with autism

New approach can reduce depression in patients with AMD-related low vision

Pain control in osteoarthritis patients

New gene therapy may be effective for fighting fungal infections in cancer patients

Over 650 000 children develop tuberculosis every year in the 22 HBCs according to new estimates

UCLA project receives $15M to restore lost memory functions in brain-injured people

Research finding offers potential therapeutic avenues for glioblastoma

Study gives parents, doctors new options to treat children with eczema

Combining NRT with varenicline improves smoking abstinence

Fabry disease awareness: an interview with Dr. Hartmann Wellhoefer, Head of Medical Affairs, Rare Disease, Shire

Oncolytics completes patient enrollment in phase II metastatic pancreatic cancer study

Novel cancer immunotherapy for dogs could benefit humans as well

Hypertension does not respond to therapy due to inadequate diagnosis

First report of spinal cord mass arising from spinal cord cell transplantation

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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