Therapy News and Research

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Protein may predict outcome of targeted mccRCC therapy

Levels of carbonic anhydrase 9 increase with the use of vascular endothelial growth factor-targeted therapy for metastatic clear-cell renal cancer, and high expression of this protein is associated with increased survival, show study results reported in European Urology.

3 Jul 2014

Beleodaq gets FDA approval for treatment of patients with peripheral T-cell lymphoma

The U.S. Food and Drug Administration today approved Beleodaq (belinostat) for the treatment of patients with peripheral T-cell lymphoma (PTCL), a rare and fast-growing type of non-Hodgkin lymphoma (NHL). The action was taken under the agency's accelerated approval program.

3 Jul 2014

Diabetes easier to control with insulin pump than self-injections?

Insulin pump therapy may be an effective alternative for people who cannot control their diabetes effectively using daily self-injections, show study findings.

3 Jul 2014

UCB, Dermira enter into licensing agreement for development, commercialization of Cimzia

UCB, a global biopharmaceutical leader, and Dermira, Inc., a privately held US-based dermatology company, announced today that they have entered into an exclusive licensing agreement for the development and future commercialization of Cimzia (certolizumab pegol) in dermatology.

3 Jul 2014

Analysis of clinical trials reveals urgent need to increase Alzheimer's drug development

Researchers at the Cleveland Clinic Lou Ruvo Center for Brain Health have conducted the first-ever analysis of clinical trials for Alzheimer's disease (AD), revealing an urgent need to increase the number of agents entering the AD drug development pipeline and progressing successfully towards new therapy treatments.

3 Jul 2014

Combination of cognitive behavioral therapy and medication reduces relapse in depressed youths

Cognitive behavioral therapy in addition to medication improves the long-term success of treatment for children and adolescents suffering from depression, a new UT Southwestern Medical Center study indicates.

3 Jul 2014

New hope for women with early-stage breast cancer

Women with early-stage breast cancer may now receive a one-dose radiation treatment at the same time as lumpectomy surgery, eliminating the need to return to the hospital daily for up to six weeks for post surgical radiation treatments.

3 Jul 2014

Antibiotic therapy: A potential game-changer for hemodialysis treatment

An antibiotic therapy known to reduce catheter-related bloodstream infections in hemodialysis patients has been shown for the first time to reduce mortality, according to a Henry Ford Health System study.

3 Jul 2014

Findings provide new insights into the basic biology of stem cells

A team of researchers from the University of California, San Diego School of Medicine, Oregon Health & Science University and Salk Institute for Biological Studies has shown for the first time that stem cells created using different methods produce differing cells.

3 Jul 2014

New meta-analysis highlights significant gaps in hepatitis C care

A new meta-analysis published online in PLOS ONE by infectious disease and epidemiology specialists from the Perelman School of Medicine at the University of Pennsylvania highlights significant gaps in hepatitis C care that will prove useful as the U.S. health care system continues to see an influx of patients with the disease because of improved screening efforts and new, promising drugs.

3 Jul 2014

Study reveals mechanism underlying abnormal fat accumulation in HIV patients

Building upon their earlier research on the biology of fat metabolism, Joslin scientists discovered that microRNAs -small RNA molecules that play important roles in regulation in many types of tissue - play a major role in the distribution and determination of fat cells and whole body metabolism.

3 Jul 2014

Lung cancer patients could benefit from new 'QTA' technique

Lung cancer patients could receive more precise treatment, and their progress could be better tracked, using a new high-tech method of non-invasive medical imaging analysis, according to a study published today by the journal PLOS ONE.

3 Jul 2014

Testosterone therapy does not increase men's risk for heart attack, shows UTMB study

Testosterone prescriptions for older men in the United States have increased more than three-fold over the past decade. Recent studies linking testosterone use with increased risk of heart attack and stroke have caused widespread concern among patients and their families.

2 Jul 2014

Surgical treatment improves survival for metastatic melanoma patients whose disease is limited to the liver

Surgical resection markedly improves survival among metastatic melanoma patients whose disease is isolated to a few areas in the liver, according to new study findings published in the July issue of the Journal of the American College of Surgeons.

2 Jul 2014

New collaborative fundraising effort focuses on AYA cancer

Leaders from Case Western Reserve University and University Hospitals this evening announced a new collaborative fundraising effort focused on Adolescent and Young Adult (AYA) cancer.

2 Jul 2014

New gene therapy for Acute Intermittent Porphyria

Angeles suffers from a severe and rare genetic disease called Acute Intermittent Porphyria (AIP). This means, one of her genes restrains her liver to produce a specific protein needed for the metabolism of the blood. During an AIP attack Angeles usually feels intense abdominal pain, and her mental status changes. Women live at an increased risk to trigger the symptoms, because porphyria is related to the menstrual cycle.

2 Jul 2014

Australian immunologists uncover additional role for antibody-making 'B cells'

A discovery by Australian immunologists, uncovering an additional role for antibody-making 'B cells', is considered important enough by the American Association of Immunologists to rank it among the top 10% of articles in the latest issue of The Journal of Immunology, off the press today.

2 Jul 2014

CHOP study: Children with specific gene variants may require higher doses of pain-control drugs

In the first genome-wide analysis of postsurgical pain in children, pediatric researchers identified variations in genes that affect a child's need for pain-control drugs. The findings suggest that at some point physicians may calibrate pain-medication dosages according to a child's individual genetic makeup.

2 Jul 2014

Researchers identify new biomarker that predicts effectiveness of glioblastoma treatment

Researchers at the University of California, San Diego School of Medicine have identified a new biomarker that predicts whether glioblastoma - the most common form of primary brain cancer - will respond to chemotherapy. The findings are published in the July print issue of Oncotarget.

2 Jul 2014

Drug everolimus fails to improve overall survival in advanced liver cancer patients

Despite strong preclinical data, the drug everolimus failed to improve overall survival in patients with advanced liver cancer, compared to placebo, according to a study in the July 2 issue of JAMA.

2 Jul 2014

Therapy News and Research

Protein may predict outcome of targeted mccRCC therapy

Beleodaq gets FDA approval for treatment of patients with peripheral T-cell lymphoma

Diabetes easier to control with insulin pump than self-injections?

UCB, Dermira enter into licensing agreement for development, commercialization of Cimzia

Analysis of clinical trials reveals urgent need to increase Alzheimer's drug development

Combination of cognitive behavioral therapy and medication reduces relapse in depressed youths

New hope for women with early-stage breast cancer

Antibiotic therapy: A potential game-changer for hemodialysis treatment

Findings provide new insights into the basic biology of stem cells

New meta-analysis highlights significant gaps in hepatitis C care

Study reveals mechanism underlying abnormal fat accumulation in HIV patients

Lung cancer patients could benefit from new 'QTA' technique

Testosterone therapy does not increase men's risk for heart attack, shows UTMB study

Surgical treatment improves survival for metastatic melanoma patients whose disease is limited to the liver

New collaborative fundraising effort focuses on AYA cancer

New gene therapy for Acute Intermittent Porphyria

Australian immunologists uncover additional role for antibody-making 'B cells'

CHOP study: Children with specific gene variants may require higher doses of pain-control drugs

Researchers identify new biomarker that predicts effectiveness of glioblastoma treatment

Drug everolimus fails to improve overall survival in advanced liver cancer patients

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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