Protein C News and Research

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Life Science Leader recognizes CMC Biologics for quality, reliability for third consecutive year

CMC Biologics, Inc., a leading global contract manufacturing organization known for technical excellence and customer satisfaction in biopharmaceutical development and commercial manufacture of protein-based therapeutics, was recognized for the third consecutive year for quality and reliability by Life Science Leader at an awards ceremony at DCAT Week '15 in New York.

19 Mar 2015

Scientists identify mystery behind cell-signaling breakdown that causes heart failure

Working with lab animals and human heart cells, scientists from Johns Hopkins and other institutions have identified what they describe as "the long-sought culprit" in the mystery behind a cell-signaling breakdown that triggers heart failure. The condition, which affects nearly 6 million Americans and 23 million people worldwide, is marked by progressive weakening and stiffening of the heart muscle and the organ's gradual loss of blood-pumping ability.

19 Mar 2015

Cardiovascular researchers identify MG53 protein necessary for repairing injured kidney cells

Cardiovascular researchers at The Ohio State University Wexner Medical Center have shown that a protein known as MG53 is not only present in kidney cells, but necessary for the organ to repair itself after acute injury. Results from this animal model study are published in the journal Science Translational Medicine.

19 Mar 2015

Austrian Centre of Industrial Biotechnology develops method to reduce production costs of valuable drugs

Imagine a loved relative suffering from cancer - and you could not afford a treatment because the drugs are too expensive. The Austrian Centre of Industrial Biotechnology (acib) developed a method with the power to reduce production costs of highly valued drugs significantly.

19 Mar 2015

New bodily process may explain low blood oxygen levels for cystic fibrosis patients with lung infection

Researchers have defined a new bodily process in mice that may explain why blood oxygen levels are lower for patients with cystic fibrosis when they get a lung infection.

19 Mar 2015

RUB biochemists gain new insights into generation, maintenance of circadian rhythms

Biochemists at the Ruhr-Universität Bochum have gained new insights into the generation and maintenance of circadian rhythms. They demonstrated that the Ras protein is important for setting the phase of such a circadian clock, as its activity determines the period length of the rhythm.

19 Mar 2015

UVA researcher identifies potential therapeutic target for myotonic muscular dystrophy

A doctor who was one of the discoverers of the gene responsible for myotonic muscular dystrophy has now identified a therapeutic that could modify progression of muscle damage and muscle dysfunction associated with the disease - issues that cause patients significant disability and deterioration in quality of life.

19 Mar 2015

New research lays groundwork for developing treatments for asthma, COPD

In diseases such as asthma and chronic obstructive pulmonary disease (COPD), the body produces too much mucus, making breathing difficult. New research from Washington University School of Medicine in St. Louis provides clues to potentially counteract inappropriate mucus production.

18 Mar 2015

Five simple nutrition tips that can positively impact your overall health

Capital BlueCross this month, National Nutrition Month, is reminding residents in central Pennsylvania and the Lehigh Valley that making even small changes to their eating habits can vastly improve their health.

18 Mar 2015

Researchers discover new metabolic mechanisms linked to macrophage polarization

A group of researchers from Washington University in St. Louis, Agios Pharmaceuticals and ITMO University has discovered new metabolic mechanisms that regulate macrophage polarization - the unique ability of these immune cells to change their specialization depending on the required task.

18 Mar 2015

UT Southwestern neuroscientists identify key brain cells that control circadian rhythms

UT Southwestern Medical Center neuroscientists have identified key cells within the brain that are critical for determining circadian rhythms, the 24-hour processes that control sleep and wake cycles, as well as other important body functions such as hormone production, metabolism, and blood pressure.

18 Mar 2015

Gentronix signs three-year technology access deal with SIMM

UK based Gentronix Limited, the specialist genetic toxicology company, today announced it has signed a three year technology access deal with one of China's most prestigious research intensive institutes, Shanghai Institute Materia Medica, Chinese Academy of Sciences.

18 Mar 2015

Laura De Laporte receives ERC grant to develop minimally invasive therapy for spinal cord injury

The research objective of Dr.-Ing. Laura De Laporte, junior group leader at DWI - Leibniz Institute for Interactive Materials in Aachen, is to develop a minimally invasive therapy for spinal cord injury. Her goal and her scientific approach to develop an injectable material with the ability to provide biochemical and physical guidance for regenerating nerves across the injury site, was selected by the European Research Council.

18 Mar 2015

Scientists examine how substances at low concentrations may impact human health

A public and scientific discussion is currently taking place focusing on the question whether substances at low concentrations may lead to health impairments in humans. For this reason, an increasing number of experimental studies to test such effects are currently conducted using different chemicals.

18 Mar 2015

Students attending Brainworks program to learn how regular exercise may help improve brain health

About 140 seventh- and eighth-graders attending Cedars-Sinai's Brainworks program March 23 will learn how hopping, skipping, jumping and other elements of a regular exercise routine may help improve brain health. An exercise station - a new feature of the 17-year-old program - will be one of nine areas where students will interact with Cedars-Sinai neurosurgeons, neurologists, neuroscientists and other health professionals.

18 Mar 2015

DNA sequence determines flexibility, stability of DNA package inside microscopic cell

To pack two meters of DNA into a microscopic cell, the string of genetic information must be wound extremely carefully into chromosomes. Surprisingly the DNA's sequence causes it to be coiled and uncoiled much like a yoyo, scientists reported in Cell.

18 Mar 2015

Scientists identify how mRNA deciphers critical information within genetic code

Case Western Reserve scientists have discovered that speed matters when it comes to how messenger RNA (mRNA) deciphers critical information within the genetic code — the complex chain of instructions critical to sustaining life. The investigators' findings, which appear in the March 12 journal Cell, give scientists critical new information in determining how best to engage cells to treat illness — and, ultimately, keep them from emerging in the first place.

18 Mar 2015

Physicians, researchers to discuss advances in cancer immunotherapies at UChicago symposium

The Ben May Department for Cancer Research at the University of Chicago will hold a day-long symposium on cancer immunotherapy for physicians and researchers.

18 Mar 2015

Anesthetics interfere with certain proteins in excitatory neurons that transmit signals

Anesthetics have been used in surgical procedures for more than 150 years, but the mechanisms by which inhaled anesthesia actually work are poorly understood. Now, researchers at Johns Hopkins Medicine have discovered that anesthetics bind to and interfere with certain proteins in excitatory neurons, which are necessary for these neurons to transmit signals involved in anesthesia and the perception of pain.

18 Mar 2015

International researchers reveal significance of water for functional protein dynamics

An international team of researchers from the CEA, the CNRS, the Institut Laue-Langevin, the Jülich Centre for Neutron Science, the University of California Irvine, the Australian Institute of Science and Technology Organisation, the Max Planck Institute Mülheim and the University of Perugia has shed light on the molecular mechanism behind the importance of water for functional protein dynamics.

18 Mar 2015

Protein C News and Research

Life Science Leader recognizes CMC Biologics for quality, reliability for third consecutive year

Scientists identify mystery behind cell-signaling breakdown that causes heart failure

Cardiovascular researchers identify MG53 protein necessary for repairing injured kidney cells

Austrian Centre of Industrial Biotechnology develops method to reduce production costs of valuable drugs

New bodily process may explain low blood oxygen levels for cystic fibrosis patients with lung infection

RUB biochemists gain new insights into generation, maintenance of circadian rhythms

UVA researcher identifies potential therapeutic target for myotonic muscular dystrophy

New research lays groundwork for developing treatments for asthma, COPD

Five simple nutrition tips that can positively impact your overall health

Researchers discover new metabolic mechanisms linked to macrophage polarization

UT Southwestern neuroscientists identify key brain cells that control circadian rhythms

Gentronix signs three-year technology access deal with SIMM

Laura De Laporte receives ERC grant to develop minimally invasive therapy for spinal cord injury

Scientists examine how substances at low concentrations may impact human health

Students attending Brainworks program to learn how regular exercise may help improve brain health

DNA sequence determines flexibility, stability of DNA package inside microscopic cell

Scientists identify how mRNA deciphers critical information within genetic code

Physicians, researchers to discuss advances in cancer immunotherapies at UChicago symposium

Anesthetics interfere with certain proteins in excitatory neurons that transmit signals

International researchers reveal significance of water for functional protein dynamics

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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