Autoantibodies News and Research

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First potential biomarker identified for postural orthostatic tachycardia syndrome

New research from The University of Toledo College of Medicine and Life Sciences strongly suggests postural orthostatic tachycardia syndrome, or POTS, is an autoimmune disorder and may help pave the way for a simple blood test that could help physicians diagnose the condition.

9 Sep 2019

UAB researchers identify biomarker for early beta cell death in Type 1 diabetes

Beta cells in the pancreas produce insulin. Their death is a key feature of Type 1 diabetes, and that loss starts long before diagnosis. However, there has been no straightforward way to measure that early loss.

8 Sep 2019

New circulating immune cell could help predict type 1 diabetes risk

A new Finnish study suggests that type 1 diabetes may in part be caused by a novel subset of immune cells. This is because these cells, called peripheral T helper cells, are found to circulate at a higher rate in children with type 1 diabetes of recent onset, as well as in healthy children who later develop the condition.

20 Aug 2019

Novel T-cell subset may have a role in development of type 1 diabetes

A study conducted at the University of Eastern Finland demonstrated that a recently described T-cell subset, so-called peripheral T helper cells, may have a role in the development of type 1 diabetes.

19 Aug 2019

Potential genomics methods discover gene signature predicting type 1 diabetes

Using cutting-edge genomics methods a gene signature predicting type 1 diabetes was discovered. This signature is detectable already before the appearance of type 1 diabetes associated autoantibodies.

8 Aug 2019

Scientists discover rare autoimmune disease triggered by testicular cancer

A new autoimmune disease has been discovered that is triggered by testicular cancer. The condition is rare, but cases are growing.

8 Jul 2019

Researchers identify autoimmune disease linked with testicular cancer

Using advanced technology, scientists at Chan Zuckerberg Biohub, Mayo Clinic and University of California, San Francisco, have discovered an autoimmune disease that appears to affect men with testicular cancer.

3 Jul 2019

Antibodies could cause arthritic pain

Antibodies that exist in the joints before the onset of rheumatoid arthritis can cause pain even in the absence of arthritis, researchers from Karolinska Institutet in Sweden report.

13 Jun 2019

Study finds potential treatment for patients with Complex Regional Pain Syndrome

A study, published today in PNAS, has found a potential treatment for patients with Complex Regional Pain Syndrome.

11 Jun 2019

Drug that targets the immune system can delay type 1 diabetes in high risk children, adults

A drug that targets the immune system can delay the onset of type 1 diabetes an average of two years in children and adults at high risk, according to findings from TrialNet's Teplizumab (anti-CD3) Prevention Study published in the New England Journal of Medicine.

10 Jun 2019

Increasing early beta-cell proliferation could halt development of type 1 diabetes

Many in-development cures for type 1 diabetes have understandably focused on tackling the autoimmune aspect of the disease before figuring out a way to replace the destroyed beta cells. But what if focusing on the beta cells first could prevent their destruction altogether?

7 May 2019

Biomolecular researcher provides comprehensive profile of B cells in rheumatoid arthritis

Biomolecular researcher Navin Varadarajan has published in Arthritis & Rheumatology journal a first-of-its-kind study - a comprehensive profile of B cells in rheumatoid arthritis.

12 Apr 2019

MUSC study provides evidence for link between 'leaky gut' and autoantibody production in HIV-positive patients

Human immunodeficiency virus, or HIV, attacks the immune system, making affected individuals more susceptible to infections. When patients with HIV are treated with antiretroviral therapy, their immune system can recover, but some of them produce self-destructive proteins, or autoantibodies.

2 Apr 2019

Better regulation of the immune system may help manage preeclampsia

Boosting the body's levels of interleukin-4 (IL-4)--an immune system protein that controls inflammation--may help manage the pregnancy complication preeclampsia, according to a new rodent study.

7 Mar 2019

Researchers reveal promising biomarker for vascular disease relapse

Researchers at Okayama University report in the journal Arthritis & Rheumatology that monitoring a particular antigen can be used for predicting relapse of the vascular disease AAV.

28 Feb 2019

New system for early detection of lupus developed

Autoimmune diseases, such as systemic lupus erythematosus or rheumatoid arthritis, are difficult to diagnose, specially in early stages. Specifically, in the case of lupus, specific antibodies aimed at antigens located in the nucleus of cells appear, including the anti-Ro/SSA.

1 Feb 2019

OU researcher and collaborators are developing new strategies for early intervention of Lupus

A University of Oklahoma researcher, Si Wu, and collaborators from the Oklahoma Medical Research Foundation and Indiana University, are developing new strategies leading to diagnosis and early intervention of Lupus, an autoimmune disease that may affect up to 1.5 million Americans.

1 Feb 2019

Newly developed risk score more effective at identifying type 1 diabetes

A new way of screening babies and adults for future risk of type 1 diabetes will be much more effective at identifying the condition than current methods, new research has concluded.

18 Jan 2019

Study follows children into adolescence to more accurately assess type 1 diabetes risk

Scientists are narrowing in on checklists of both errant genes and the environmental factors that could trigger those genes to more accurately assess type 1 diabetes risk and help children and their families avoid it.

3 Jan 2019

FDA supports C-Path's Type 1 Diabetes Consortium to pursue biomarker qualification

Critical Path Institute (C-Path) announced today that its Type 1 Diabetes (T1D) Consortium has received a positive response to its Letter of Intent (LOI) from the U.S. Food and Drug Administration (FDA) detailing the FDA's decision to accept the consortium's Biomarker Initiative project into the Center for Drug Evaluation and Research (CDER) Biomarker Qualification Program (BQP).

19 Dec 2018