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The promise of RNA medicine is targeted and personalized

The development of messenger RNA (mRNA) vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has only increased the impetus in this field.

11 May 2022

Research highlight reports on the observed differences in transmissibility and pathogenicity of Omicron vs. earlier variants of SARS-CoV-2

A new paper published in Signal Transduction and Targeted Therapy reports the observed differences in transmissibility and pathogenicity of Omicron vs. earlier variants of SARS-CoV-2.

10 May 2022

Marine bioactive compounds against SARS-CoV-2

A new review paper published in the journal Environmental Science and Pollution Research aimed to determine the possibilities of using biologically active compounds derived from various chemical classes of marine organisms against SARS-CoV-2 infection at various stages of the life cycle of the virus.

6 May 2022

Effects of diet on COVID-19 outcomes

A new study explores the effects of diet on COVID-19 outcomes.

5 May 2022

Therapeutic promise of CAR-T cell bispecific engagers against SARS-CoV-2

A new paper describes a novel method, using a specific molecule to engage T cell receptors and the virus receptor, the angiotensin-converting enzyme 2, at the same time.

28 Apr 2022

Study describes ultra-structure of Nipah virus surface glycoprotein

A team of US-based scientists has recently demonstrated the cryo-electron microscopic structure and antigenicity of the attachment glycoprotein of the Nipah virus.

27 Apr 2022

New discovery about nature’s ‘high-end machinery’ could have big implications for biology

Working with tiny bacteria, Michigan State University researchers led by Lee Kroos have made a discovery that could have big implications for biology.

26 Apr 2022

The potency of halicin against the main protease of SARS-CoV-2

A new paper published in Current Research in Chemical Biology discusses the potential of a molecule called halicin against SARS-CoV-2.

26 Apr 2022

ST6Gal-I–mediated sialylation of the EGFR modulates cell mechanics and enhances cancer invasion

For more than two decades, University of Alabama at Birmingham researcher Susan Bellis, Ph.D., has studied how the addition of sialic acid to various proteins increases cancer resistance and oncogenicity.

22 Apr 2022

SARS-CoV-2 spike protein disrupts lipid metabolism resulting in liver, heart & kidney damage

A new study describes the impact of SARS-CoV-2 on host lipid metabolism.

21 Apr 2022

High performance microplates for enhanced cell growth and survival

The Sero Krystal™ PDL range of coated microplates from Porvair Sciences set a new benchmark for reproducible cell culture even with challenging cell types.

From Porvair Sciences Limited 20 Apr 2022

Using customized 'mini-antibodies' to mitigate chronic inflammation

Researchers at the Universities of Bonn and Sao Paulo have succeeded in mitigating chronic inflammation in mice using customized "mini-antibodies."

19 Apr 2022

Avasimibe inhibits SARS-CoV-2 and boosts T-cell responses

Researchers demonstrate that avasimibe-mediated inhibition of ACAT blocks the entry and fusion of SARS-CoV-2 in different cell types.

18 Apr 2022

Cryo-electron microscopy shows how Omicron BA.2 structure differs from BA.1 substantially

Researchers used cryogenic electron microscopy (cryo-EM) to determine the structure of the spike (S) protein of BA.2 sub-variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC) and compared them with previously determined S structures of Omicron's BA.1 sub-variant.

11 Apr 2022

Study identifies a novel class of angiotensin receptor blockers that interfere with SARS-CoV-2 spike – ACE2 interaction

Study analyzed several naturally-occurring amino acid variations found in the extended loop harboring the SARS-CoV-2 S1/S2 cleavage site

A recent study analyzed the polymorphisms in the SARS-CoV-2 spike proteins' S1/S2 subunits.

30 Mar 2022

The different actions of CBD in SARS-CoV-2 infection

An article has described the role of cannabidiol as a potential inhibitor of hyperinflammation in SARS-CoV-2 infection.

29 Mar 2022

Researchers show how an important inhibitor binds to the A2A receptor

The A2A receptor regulates how vigorously the innate immune system attacks diseased cells.

25 Mar 2022