Gliomas News and Research

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NCCN publishes new easy-to-understand patient education resources focused on brain cancer

The National Comprehensive Cancer Network has published the NCCN Guidelines for Patients and NCCN Quick Guide sheets for Brain Cancer - Gliomas—the first in a series of patient education resources focused on Brain Cancer.

10 Jan 2017

New research suggests novel combination approach to fight against gliomas

"Devastating" and "dismal." That's how leading researchers describe the present outlook for malignant brain tumors. The median survival rate for patients with glioblastoma multiforme, or GBM, is a mere 14.2 months.

4 Jan 2017

Novel genomics model allows personalized approach to radiation therapy

Cancer therapeutics is currently in the era of precision medicine - personalized medicine for individual patients based on their tumor biology.

20 Dec 2016

Researchers identify attractive drug candidate to target glioma tumors

In a paper published today in Cancer Research, researchers: 1) identify a biomarker enzyme associated with aggressive glioma brain tumors, 2) reveal the regulatory mechanism for that enzyme, and 3) demonstrate potent efficacy, using a mouse model of glioma, for a small molecule inhibitor they have developed.

16 Dec 2016

Scientists discover new biomarker to help determine aggressiveness of brain cancer

Researchers at UT Southwestern Medical Center have found a new biomarker for glioma, a common type of brain cancer, that can help doctors determine how aggressive a cancer is and that could eventually help determine the best course of treatment.

6 Dec 2016

Ancient Japanese art inspires groundbreaking technique to create ‘artificial brains’

The ancient Japanese art of flower arranging was the inspiration for a groundbreaking technique to create tiny "artificial brains" that could be used to develop personalized cancer treatments.

6 Dec 2016

Genetic differences between brain cancer cells and normal tissues could offer clues to tumor behavior

Two recently discovered genetic differences between brain cancer cells and normal tissue cells -- an altered gene and a snippet of noncoding genetic material -- could offer clues to tumor behavior and potential new targets for therapy, Johns Hopkins scientists report.

2 Dec 2016

Researchers identify simple, inexpensive tool for assessing prognosis of pediatric brain tumors

A multi-institutional group of researchers, led by investigators at Children's Hospital Los Angeles and the University of Michigan, have identified a simple and inexpensive tool for assessing the prognosis of pediatric brain tumors called ependymomas.

23 Nov 2016

New study describes role of protein that is crucial for melanoma cell survival

The main goals of the Melanoma Group at the Spanish National Cancer Research Centre are to identify biomarkers of tumour progression and to validate novel therapeutic targets in melanoma.

21 Nov 2016

Experimental cancer imaging tool shows promise in illuminating brain tumors during surgery

An experimental cancer imaging tool that makes tumors glow brightly during surgery has shown promise again in a new Penn Medicine clinical study, this time in patients with brain cancer.

17 Nov 2016

Researchers develop MRI-based method that can track progression of genetically mutated gliomas

UT Southwestern Medical Center researchers have developed an MRI-based method that can track the state and progression of a common type of genetically mutated brain cancer.

17 Oct 2016

Researchers report high response rate with single drug in phase I/II trial of paediatric brain cancer

A high response rate with a single drug in a phase I/II trial of paediatric brain tumour has set the stage for combination therapy with higher response and lower toxicity, researchers reported at the ESMO 2016 Congress in Copenhagen.

7 Oct 2016

Study identifies prognostic value of IDH and CIC mutations for grade II/III glioma patients

NRG Oncology investigators have identified two biomarkers that are prognostic of overall and progression-free survival for patients with lower-grade gliomas.

4 Oct 2016

Researchers uncover new molecular causes of brain cancer and leukemia

A joint research published today in Nature Communications has shown new molecular causes of brain cancer and leukemia.

14 Sep 2016

Wistar scientists discover novel mechanism that helps tumors adapt to hypoxia

One of the many reasons tumors are so difficult to treat is that they are able to adapt whenever they are exposed to unfavorable conditions.

9 Aug 2016

Johns Hopkins researchers develop lab test that accurately predicts glioblastoma aggression and spread

Johns Hopkins Medicine researchers report they have developed an experimental laboratory test that accurately clocks the “speed” of human brain tumor cell movement along a small glass “track.”

13 Jun 2016

Giving chemotherapy after radiotherapy delays rare brain tumour growth

GIVING chemotherapy after radiotherapy delays further growth of a rare type of brain tumour, increasing the number of patients alive at five years from 44 per cent to 56 per cent.

6 Jun 2016

TSRI study shows how specific gene mutation promotes growth of aggressive tumors

Scientists at The Scripps Research Institute have caught a cancer-causing mutation in the act. A new study shows how a gene mutation found in several human cancers, including leukemia, gliomas and melanoma, promotes the growth of aggressive tumors.

27 May 2016

Experimental therapy stops glioblastoma, high-grade gliomas in human cells and mouse models

Researchers report in the journal Cancer Cell an experimental therapy that in laboratory tests on human cells and mouse models stops aggressive, treatment-resistant and deadly brain cancers called glioblastoma and high-grade gliomas.

10 May 2016

Research provides new insight into cellular composition of IDH1-mutant gliomas

Winner of the Preuss Research Award, Andrew Venteicher, MD, PhD, presented his research, Cellular Architecture of Human IDH1-mutant Gliomas Revealed Using Single-cell RNA Sequencing, during the 2016 American Association of Neurological Surgeons Annual Scientific Meeting.

5 May 2016