Hepatocellular Carcinoma News and Research

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Hepatocellular Carcinoma is a type of adenocarcinoma, the most common type of liver tumor.

Novel micro-cubes can efficiently deliver hydrophobic anti-tumor drug to cancer cells

Many potent anti-cancer drugs have major drawbacks -- they fail to mix with water, which means they will have a limited solubility in blood, and they lack selectivity to cancer cells.

29 Jun 2017

MILabs installs advanced microCT system at National Yang-Ming University in Taipei

MILabs installs its industry-leading microCT system at The Center of Excellence for Translational Imaging at National Yang-Ming University in Taipei of East Asia.

28 Jun 2017

Stivarga receives expanded FDA approval for treatment of liver cancer

The U.S. Food and Drug Administration today expanded the approved use of Stivarga (regorafinib) to include treatment of patients with hepatocellular carcinoma (HCC or liver cancer) who have been previously treated with the drug sorafenib.

28 Apr 2017

Study reveals promising results for primary liver cancer patients treated with SIR-Spheres Y-90 resin microspheres

Patients with advanced or inoperable Hepatocellular Carcinoma (HCC) who usually received one or two treatments with liver-directed SIR-Spheres Y-90 resin microspheres in the 459-patient French SARAH study had similar survival compared to patients who received standard twice-daily systemic treatment with sorafenib, but with less than half the number and significantly fewer severe treatment-related adverse effects and significantly better Quality of Life, according to data presented here at The International Liver Congress™ 2017.

26 Apr 2017

Spermidine supplement may prolong lifespan, prevent liver fibrosis and cancer

Spermidine-; a compound found in foods like aged cheese, mushrooms, soy products, legumes, corn and whole grains-; seems to prevent (at least in animal models) liver fibrosis and hepatocellular carcinoma, which is the most common type of liver cancer. There is also some evidence that it may prolong lifespan, according to a study published recently in the journal Cancer Research.

20 Apr 2017

Research reveals how liver progenitor cells contribute to development of hepatic tumors

The malignant transformation of hepatocytes is the origin of most hepatocellular carcinomas, an aggressive type of liver cancer with high mortality rates. But these cells do not act alone.

18 Apr 2017

Researchers aim to examine therapeutic effect of iPS-ML producing interferon-β on liver cancer

All causes of the most common form of liver cancer, hepatocellular carcinoma, are not yet known, but the risk of getting it is increased by hepatitis B or C, cirrhosis, obesity, diabetes, a buildup of iron in the liver, or a family of toxins called aflatoxins produced by fungi on some types of food.

29 Mar 2017

Research reveals dual role of TGF-beta cytokine in liver cancer

Recent research results from the TGF-beta and cancer research group at the Bellvitge Biomedical Research Institute, within IT-Liver, a collaborative European action among several research groups led by Dr. Isabel Fabregat, provide a better understanding of the role of the TGF-beta cytokine in liver cancer.

29 Mar 2017

Study provides insight into how microRNA may amplify effects of drug treatment in liver cancer

Treatment options for liver cancer are often limited and almost exclusively involve transplantation if possible, or local chemoembolization and radiofrequency ablation.

17 Feb 2017

Proscia collaborates with Samsung Medical Center to develop tools for metastasis prediction in lung cancer

Proscia Inc., a data solutions provider for digital pathology, and Samsung Medical Center, South Korea’s preeminent clinical and biomedical research institute, today announced a partnership focused on developing tools that enable predictive medicine in the fight against cancer.

16 Feb 2017

Dietary fructose consumption may increase risk for NASH in children and adolescents

Recent research suggests that dietary fructose intake may increase serum uric acid concentrations and that both uric acid concentration and fructose consumption may be increased in individuals with non-alcoholic fatty liver disease.

14 Feb 2017

New analysis reveals low incidence of liver cancer in patients with cirrhosis

Although one of the most serious complications of cirrhosis is liver cancer, or hepatocellular carcinoma (HCC), an analysis of health records revealed that the 10-year incidence of HCC in UK patients with cirrhosis is four percent or lower.

1 Feb 2017

New drugs that target neighbour proteins may help halt cancer progression

Cancer is caused by an accumulation of genetic changes in a cell, that overcome the normal checks and balances leading to uncontrolled growth. A complex, interacting network of proteins controls all of a cell's processes, from metabolism to growth and division.

24 Jan 2017

MGH-developed CTC-iChip with digital PCR assay improves detection of early-stage liver cancer

Use of an advanced form of the commonly used polymerase chain reaction (PCR) method to analyze circulating tumor cells (CTCs) may greatly increase the ability to diagnose early-stage cancer, increasing the likelihood of successful treatment.

20 Jan 2017

AAV-based gene therapy to treat liver disorders advances into human testing

Liver-directed gene therapy delivered using adeno-associated viral (AAV) vectors to treat diseases such as hemophilia have advanced into human testing.

30 Dec 2016

Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Fred Hutchinson Cancer Research Center announced its first-ever grants from its newly established Evergreen Fund to spur researchers' efforts to advance bold ideas toward creating or partnering with a commercial entity.

28 Dec 2016

Special Issue on digestive cancers offers five articles from experts in Latin America

ecancermedicalscience has published a new Special Issue on digestive cancers in Latin America, bringing together five articles from experts in the region.

21 Dec 2016

Scientists unravel novel role of signalling protein in common type of liver cancer

The most common type of liver cancer, called Hepatocellular carcinoma, is one of the most prevalent tumours worldwide.

21 Dec 2016

Scientists unveil role of NOX4 protein as inhibitor of invasion and metastasis of liver tumor cells

Researchers of the TGF-beta and Cancer group of Bellvitge Biomedical Research Institute, in collaboration with King's College London, have unveiled the role of NADPH oxidase NOX4 as an inhibitor of the epithelial-amoeboid transition, a process that contributes to the migration and invasion of tumor cells.

20 Dec 2016

HCV patients treated with DAA therapy not at increased risk of developing liver cancer, study finds

A new study presented this week at The Liver Meeting — held by the American Association for the Study of Liver Diseases — found patients with hepatitis C who take direct-acting antiviral medication are at no higher risk for developing liver cancer than those who do not take the medication.

11 Nov 2016