Lymph Nodes News and Research

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New study reveals key tissues involved in HIV rebound after treatment

In findings that have implications for potential new HIV therapies, researchers from Texas Biomedical Research Institute (Texas Biomed) used genetic sequencing techniques on the nonhuman primate version of the virus to identify that lymph nodes in the abdomen are the leading source of rebound infection after the first week of stopping antiretroviral treatment.

24 Jan 2024

mRNA therapy revives p53 to combat ovarian tumors

Ovarian cancer is often very aggressive and responds poorly to the therapies currently available. A recent study by Goethe University Frankfurt and University Hospital Frankfurt offers hope that this could change in the medium term.

24 Jan 2024

Unveiling hidden TB risk with cutting-edge techniques

A novel approach to studying the progression of tuberculosis (TB) from infection to disease has identified and treated people at increased risk of developing the disease that current methods of testing would not.

22 Jan 2024

Oxford launches LEGACY03 trial to unravel age-related vaccine mysteries

Vaccines are the most effective way to prevent infectious diseases (NHS, 2023) however, people respond to them in different ways.

18 Jan 2024

Mathematical modeling demonstrates efficacy of combinational drug therapy for breast cancer treatment

Researchers use a mathematical model to assess the efficacy of a new combinational therapy of AZD9496 and palbociclib for breast cancer treatment.

18 Jan 2024

New approach using ultrasound-guided drug delivery effectively targets lymph node metastasis

Researchers at Tohoku University have discovered a new approach for treating lymph node metastasis. Anticancer drugs are administered directly into the LNs under ultrasound guidance (Lymphatic Drug Delivery System or LDDS) to target sentinel lymph nodes (LNs) and generate antitumor effects locally, preventing distant metastasis.

12 Jan 2024

Promising PET scanner tool developed for rare medullary thyroid cancer

A newly developed PET imaging agent has been found to be effective in identifying medullary thyroid cancer (MTC) in preclinical and clinical studies, according to research published in the January issue of The Journal of Nuclear Medicine.

11 Jan 2024

Study reveals mangos attenuates potential against colon cancer

The chemo-preventive potential of Mangiferin (MF) (mango).

10 Jan 2024

Gut microbiota linked to social anxiety behaviors

Study reveals that gut microbiota from individuals with social anxiety disorder (SAD) can induce social fear behaviors in mice, suggesting a causal role of gut microbes in modulating behaviors relevant to SAD.

2 Jan 2024

Spatial profiling predicts recurrence of Hodgkin lymphoma after bone marrow transplant

Cedars-Sinai Cancer investigators have discovered a new way to predict whether a cancer of the immune system will recur in patients treated with a bone marrow transplant.

22 Dec 2023

Study exposes racial disparities in Lyme disease diagnosis and treatment times

Study reveals racial disparities in Lyme disease diagnosis and treatment, with Black patients experiencing longer delays and higher risks of disseminated disease compared to White patients.

14 Dec 2023

New combination treatment offers hope for older patients with mantle cell lymphoma

The phase 2 trial PrE0405 met its primary endpoint, achieving a complete response (CR) rate of 85% in 33 patients over the age of 60 with mantle cell lymphoma (MCL) who received bendamustine and rituximab, a standard chemo-immunotherapy treatment, along with venetoclax, which is investigational in this setting.

11 Dec 2023

Lymphatic fluid from surgical drains could inform more precise treatments for head and neck cancer

Lymphatic fluid from surgical drains, which is usually tossed in the trash, is a treasure in the hands of University of Pittsburgh and Washington University School of Medicine in St. Louis researchers who found that this liquid could inform more precise treatments for patients with head and neck cancer caused by human papillomavirus (HPV).

11 Dec 2023

Unmasking the culprits behind long-term arm problems in breast cancer patients

A new review paper was published in Oncotarget's Volume 14 on December 1, 2023, entitled, "Risk factors for long-term arm morbidities following breast cancer treatments: A systematic review."

11 Dec 2023

Study reveals genetic roots of hodgkin lymphoma, offering hope for new treatments

A Stanford Medicine-led, international study of hundreds of samples from patients with Hodgkin lymphoma has shown that levels of tumor DNA circulating in their blood can identify who is responding well to treatment and others who are likely to experience a disease recurrence - potentially letting some patients who are predicted to have favorable outcomes forgo lengthy treatment.

11 Dec 2023

Key role of ion and water influx in T cell migration uncovered

Research reveals that T cell migration relies on ion and water influx for actin polymerization and movement, with the WNK1 kinase playing a critical role in regulating these processes, offering new insights into adaptive immunity.

10 Dec 2023

Researchers discover next-gen lipid nanoparticles for muscle-focused mRNA delivery

A team of researchers based at the University of Toronto's (U of T) Leslie Dan Faculty of Pharmacy has discovered a novel ionizable lipid nanoparticle that enables muscle-focused mRNA delivery while minimizing off-target delivery to other tissues.

8 Dec 2023

Study underscores need for primary prevention in advanced breast cancer

While regular screenings may decrease the chance of diagnosis of advanced breast cancer in some women and lead to a 20% reduction in breast cancer mortality, other women will be diagnosed with advanced breast cancer despite screening at regular intervals.

7 Dec 2023

Neoadjuvant chemotherapy can eliminate need for regional nodal irradiation in breast cancer

For patients whose breast cancer converted from lymph node-positive to lymph node-negative disease after neoadjuvant chemotherapy, skipping adjuvant regional nodal irradiation (RNI) did not increase the risk of disease recurrence or death five years after surgery, according to results from the NRG Oncology/NSABP B-51/RTOG 1304 clinical trial presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.

6 Dec 2023

Sympathetic nervous system and immune interplay: Key to metabolic regulation

A review in Advanced Science explores the interaction between the immune system and the sympathetic nervous system in regulating vital metabolic organs like the pancreas, liver, and adipose tissues. This comprehensive analysis provides insights into the neuroimmune relationships affecting metabolism, offering potential new therapeutic strategies for metabolic diseases.

5 Dec 2023

Lymph Nodes News and Research

New study reveals key tissues involved in HIV rebound after treatment

mRNA therapy revives p53 to combat ovarian tumors

Unveiling hidden TB risk with cutting-edge techniques

Oxford launches LEGACY03 trial to unravel age-related vaccine mysteries

Mathematical modeling demonstrates efficacy of combinational drug therapy for breast cancer treatment

New approach using ultrasound-guided drug delivery effectively targets lymph node metastasis

Promising PET scanner tool developed for rare medullary thyroid cancer

Study reveals mangos attenuates potential against colon cancer

Gut microbiota linked to social anxiety behaviors

Spatial profiling predicts recurrence of Hodgkin lymphoma after bone marrow transplant

Study exposes racial disparities in Lyme disease diagnosis and treatment times

New combination treatment offers hope for older patients with mantle cell lymphoma

Lymphatic fluid from surgical drains could inform more precise treatments for head and neck cancer

Unmasking the culprits behind long-term arm problems in breast cancer patients

Study reveals genetic roots of hodgkin lymphoma, offering hope for new treatments

Key role of ion and water influx in T cell migration uncovered

Researchers discover next-gen lipid nanoparticles for muscle-focused mRNA delivery

Study underscores need for primary prevention in advanced breast cancer

Neoadjuvant chemotherapy can eliminate need for regional nodal irradiation in breast cancer

Sympathetic nervous system and immune interplay: Key to metabolic regulation

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