Protein Expression News and Research

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Research uncovers a new way to boost the effectiveness of RNA therapies

Investigators from the Smidt Heart Institute at Cedars-Sinai have identified how biological pacemaker cells - cells that control your heartbeat - can "fight back" against therapies to biologically correct abnormal heartbeat rates.

20 Dec 2022

Protein expression signature distinguishes early from late stage diffuse alveolar damage

Researchers identified a protein expression signature that can distinguish early diffuse alveolar damage (DAD) from late DAD in coronavirus disease 2019 (COVID-19) patients.

15 Dec 2022

Discovery of cellular uptake pathway for larger molecules can be harnessed to create new drugs

A fundamental challenge in drug development is the balance between optimizing a drug's lock-and-key fit with its target and the drug's ability to make its way across the cellular membrane and access that target.

8 Dec 2022

Comparison of blood plasma protein expression in mild, moderate, and severe COVID-19 identifies novel disease severity biomarkers

Researchers evaluated blood plasma proteins to identify new targets for COVID-19 treatment approaches and prevent complications associated with severe illness.

5 Dec 2022

Fragment crystallizable receptor-effector functions as a key correlate for pan-sarbecovirus vaccine development

Researchers elucidated pan-sarbecovirus immune protection mechanisms by utilizing a Venezuelan equine encephalitis virus-vectored vaccine panel that covered bat strains to human strains.

30 Nov 2022

Study on the immunogenicity of monkeypox virus messenger ribonucleic acid-based vaccine candidates

In a new study, researchers developed two monkeypox (MPX) virus (MPXV) quadrivalent messenger ribonucleic acid (mRNA) vaccines, mRNA-A-lipid nanoparticle (LNP) and mRNA-B-LNP.

28 Nov 2022

Sino Biological announces construction of its new US-based center for bioprocessing

Sino Biological, Inc., a biotechnology company listed on the Shenzhen stock exchange subsidiary ChiNext, which provides biological research reagents and related technical contract research services, is pleased to announce the formal signing of a lease with Hines and initiation of construction on its new Center for Bioprocessing at its Levit Green facility in Houston, Texas USA.

From Sino Biological Inc. 24 Nov 2022

Over 440 SCI articles published! BGI’s cancer genetics and cell research fuels innovation

BGI has currently published over 440 SCI (Science Citation Index) papers in the field of cancer research, with a cumulative impact factor of over 4,000 points.

From BGI Genomics 23 Nov 2022

Novel mRNA vaccines encoding Monkeypox virus proteins show promise in preclinical studies

In a recent study posted to the bioRxiv* preprint server, researchers in China demonstrated the efficacy of three messenger ribonucleic acid (mRNA) technology-based Monkeypox virus (MPXV) vaccines in combating a lethal Vaccinia virus (VACV) challenge in mice models.

22 Nov 2022

SARS-CoV-2 open reading frame 3c protein found to be targeted selectively to mitochondria

Researchers presented a functional analysis of the SARS-CoV-2 open reading frame 3c (ORF3c) protein.

17 Nov 2022

Study of natural killer lymphocytes transcriptionally reprogrammed by vaccinia virus

In a recent study posted to the bioRxiv* preprint server, researchers evaluated responses of natural killer (NK) lymphocytes to VACV (vaccinia virus) infections in vivo.

16 Nov 2022

Protein levels in lung tumors may predict prognosis, improve treatment and diagnostics

Lung cancer is the leading cause of cancer deaths globally and a top cause of cancer deaths in the Military Health System.

15 Nov 2022

What are the current challenges and future directions of mRNA nanomedicine?

Researchers presented challenges related to the clinical translation of messenger ribonucleic acid (mRNA) technology, recent innovations and future directions to improve the clinical efficacy of mRNA nanomedicine.

15 Nov 2022

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

Researchers investigated the change in the stability, antigenicity, and protein expression of the SARS-CoV-2 spike protein trimer using structure-directed mutagenesis to alter a cavity in the core of the spike protein.

14 Nov 2022

Protein Expression News and Research

Research uncovers a new way to boost the effectiveness of RNA therapies

Protein expression signature distinguishes early from late stage diffuse alveolar damage

Discovery of cellular uptake pathway for larger molecules can be harnessed to create new drugs

Comparison of blood plasma protein expression in mild, moderate, and severe COVID-19 identifies novel disease severity biomarkers

Fragment crystallizable receptor-effector functions as a key correlate for pan-sarbecovirus vaccine development

Study on the immunogenicity of monkeypox virus messenger ribonucleic acid-based vaccine candidates

Sino Biological announces construction of its new US-based center for bioprocessing

Over 440 SCI articles published! BGI’s cancer genetics and cell research fuels innovation

Novel mRNA vaccines encoding Monkeypox virus proteins show promise in preclinical studies

SARS-CoV-2 open reading frame 3c protein found to be targeted selectively to mitochondria

Study of natural killer lymphocytes transcriptionally reprogrammed by vaccinia virus

Protein levels in lung tumors may predict prognosis, improve treatment and diagnostics

What are the current challenges and future directions of mRNA nanomedicine?

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

How mRNA vaccines work without an added adjuvant

MicroRNAs can upregulate proteins in addition to downregulating protein production

Novel branched ionizable lipid greatly increases the efficiency of mRNA delivery

COVID-19 amplifies damage to the central nervous system in Alzheimer's disease

Beyond vaccines: emerging technologies capable of unlocking the promise of biologically targeted mRNA therapeutics

What is the impact of SARS-CoV-2 on HIV-1 infectivity?

Industry Focus eBook - Protein Analysis (3rd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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