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New oral antiretroviral shows potential as long-acting HIV pre-exposure prophylaxis

A new HIV antiretroviral shows promise as a long-acting, oral prophylactic agent, according to a new study by Izzat Raheem, Tracy Diamond and colleagues from Merck & Co., Inc., Rahway, NJ, USA, published August 26th in the open-access journal PLOS Biology.

26 Aug 2025

Groundbreaking method captures microbial memory at the earliest stages of colony growth

Bacteria aren't just mindless microbes. New research from the Hebrew University of Jerusalem reveals that single bacterial cells can carry a "memory" of their past environments-passing it down through generations-before eventually forgetting.

26 Aug 2025

Indole chemistry breakthrough opens doors for more effective drug synthesis

Indole, a molecule made up of a six-membered benzene ring fused to a five-membered ring containing nitrogen, forms the core structure of many biologically active compounds.

25 Aug 2025

Gut bacteria and insomnia influence each other in small but significant ways, study shows

Scientists used Mendelian randomisation to explore the two-way relationship between gut microbiota and insomnia, analyzing GWAS data from over 386,000 individuals and two major microbiome cohorts. The study found only limited taxa surviving strict correction, suggesting small but causal links that highlight the gut–brain axis in sleep health.

21 Aug 2025

Research shows how lysosomes respond to stress

New research, published today in the journal Science, shows how lysosomes - organelles that act like cells' waste disposal system - respond to stress by becoming abnormally bloated, a process called lysosomal vacuolation that is associated with numerous diseases.

21 Aug 2025

Fish oil supplementation can reduce risk of developing type 2 diabetes in prediabetic individuals

Type 2 diabetes (T2D) has become one of the leading chronic diseases worldwide in terms of both incidence and mortality.

20 Aug 2025

Improving gene therapy safety with human kidney organoids

Ryuji Morizane, MD, PhD, of the Department of Medicine at Massachusetts General Hospital, is the senior/corresponding author of a new paper published in Signal Transduction and Targeted Therapy, "AAV for gene therapy drives a nephrotoxic response via NFκB in kidney organoids."

19 Aug 2025

It’s almost flu season. Should you still get a shot, and will insurance cover it?

For parents of school-aged children, the fall to-do list can seem ever-growing. Buy school supplies. Fill out endless school forms.

18 Aug 2025

Gene editing restores hearing and balance in adult mice with DFNA41 deafness

Zheng-Yi Chen, DPhil, associate scientist at the Eaton-Peabody Laboratories, and Ines and Fredrick Yeatts Chair in Otolaryngology, at Mass Eye and Ear, is the senior and co-corresponding author of a paper published in the Journal of Clinical Investigation, "Single Dose Genome Editing Therapy Rescues Auditory and Vestibular Functions in Adult Mice with DFNA41 Deafness."

14 Aug 2025

Pregabalin raises heart failure risk in older adults compared to gabapentin, study finds

A large Medicare cohort study found that older adults prescribed pregabalin had a significantly higher risk of developing heart failure compared to those prescribed gabapentin. The elevated risk was most pronounced in individuals with pre-existing cardiovascular disease, especially women and White patients.

13 Aug 2025

New diagnostic tool offers rapid, low-cost blood test for multiple diseases

Researchers at Arizona State University have developed a breakthrough diagnostic tool that could transform how quickly and reliably we detect illnesses like COVID-19, Ebola, AIDS or Lyme disease. The test uses just a single drop of blood, costs a couple of dollars and delivers results in only 15 minutes.

13 Aug 2025

Congress looks to ease restrictions on veterans’ use of non-VA clinics and hospitals

John-Paul Sager appreciates the care he has received at Department of Veterans Affairs hospitals and clinics, but he thinks it should be easier for veterans like him to use their benefits elsewhere.

6 Aug 2025

Hypoglossal nerve stimulator shows promise for treating sleep apnea in children with Down syndrome

Sleep apnea, or difficulty breathing at night, is common among children with Down syndrome-affecting up to 80% compared to just 5% of the general pediatric population.

5 Aug 2025

New Swiss study probes lingering fatigue after Legionnaires' disease

Researchers in Switzerland launched the LongLEGIO study to compare the long-term health impacts of Legionnaires’ disease and other bacterial pneumonias. Baseline data reveal key differences in comorbidities and quality of life between the groups, with follow-up underway.

4 Aug 2025

Q News and Research

New oral antiretroviral shows potential as long-acting HIV pre-exposure prophylaxis

Groundbreaking method captures microbial memory at the earliest stages of colony growth

Indole chemistry breakthrough opens doors for more effective drug synthesis

Gut bacteria and insomnia influence each other in small but significant ways, study shows

Research shows how lysosomes respond to stress

Fish oil supplementation can reduce risk of developing type 2 diabetes in prediabetic individuals

Improving gene therapy safety with human kidney organoids

It’s almost flu season. Should you still get a shot, and will insurance cover it?

Gene editing restores hearing and balance in adult mice with DFNA41 deafness

Pregabalin raises heart failure risk in older adults compared to gabapentin, study finds

New diagnostic tool offers rapid, low-cost blood test for multiple diseases

Congress looks to ease restrictions on veterans’ use of non-VA clinics and hospitals

Hypoglossal nerve stimulator shows promise for treating sleep apnea in children with Down syndrome

New Swiss study probes lingering fatigue after Legionnaires' disease

Unraveling the mysteries of post-acute infection syndromes

New method genetically blocks mosquitoes from transmitting malaria

Novel DNA plasmid therapy shows high success rate in treating chronic pain in dogs

EU initiative puts nutrition at the heart of diabetes care

Ancient viral DNA found to regulate human gene expression

Acorn-based coffee boosts antioxidants with minimal health risk

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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