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New type of drug shows promise for chronic lymphocytic leukemia

A new type of engineered drug candidate has shown promise in treating chronic lymphocytic leukemia in both test tube and early animal tests, a new study shows.

29 Jun 2007

New genetic test advances detection and diagnosis of muscular dystrophy

A new genetic test targeting the most common types of muscular dystrophy--those caused by mutations in the dystrophin gene--is far quicker with greater accuracy and sensitivity than existing tests.

28 Jun 2007

Scientists identify gene responsible for one type of Charcot-Marie-Tooth disorder

Scientists have identified the gene responsible for one type of Charcot-Marie-Tooth disorder, a common inherited neurological disease, thanks to the chance appearance of a strain of impaired 'pale tremor' mice in a University of Michigan research laboratory.

23 Jun 2007

Researchers develop artificial blood vessels from muscle-derived stem cells and a biodegradable polymer

University of Pittsburgh School of Medicine investigators have engineered artificial blood vessels from muscle-derived stem cells (MDSCs) and a biodegradable polymer that exhibit extensive remodeling and remain free of blockages when grafted into rats.

19 Jun 2007

Scientists link cell's protein recycling systems

Many age-related neurological diseases are associated with defective proteins accumulating in nerve cells, suggesting that the cell's normal disposal mechanisms are not operating correctly.

17 Jun 2007

New contributor to aggressive cancers

Mutations in the cell adhesion molecule known as integrin alpha 7 (integrin 7) lead to unchecked tumor cell proliferation and a significantly higher incidence in cancer spread, or metastasis, in several cancer cell lines, report researchers at the University of Pittsburgh School of Medicine in a study published in the Journal of the National Cancer Institute.

8 Jun 2007

In mice, drug protects against diabetes and atherosclerosis

Blocking a single protein with an experimental drug prevented and treated both type 2 diabetes and atherosclerosis in laboratory mice that had been fed unhealthy diets and were genetically predisposed to these common killers, according to an article published online in Nature.

8 Jun 2007

Combining molecular imaging technologies to stop/prevent heart attacks

The use of combined imaging technologies may hold the key to stopping and even preventing heart attacks, according to research reported at the 54th Annual Meeting of SNM, the world's largest society for molecular imaging and nuclear medicine professionals.

5 Jun 2007

Fat protein cuts blood vessel inflammation, may help heart

A natural substance secreted by fat cells can protect blood vessels from the damaging effects of inflammation, one of the factors that contribute to heart disease.

3 Jun 2007

Research points to a broadly-protective HIV vaccine

New research conducted at the Uniformed Services University of the Health Sciences (USU) suggests that it may be possible to develop a vaccine that protects against the myriad strains of the HIV virus.

1 Jun 2007

New animal model for Lassa fever

Scientists at the Southwest Foundation for Biomedical Research have developed a new tool in the battle against a potential biological weapon, Lassa fever, which kills several thousand people each year and leaves thousands more with disabilities such as deafness and liver damage.

1 Jun 2007

Study looks at brain damage that occurs after stroke

Brain damage that occurs even days after a stroke, increasing stroke size and devastation, is the focus of researchers trying to identify new treatments.

1 Jun 2007

Gene therapy provides hope for peripheral neuropathy

Researchers from the University of Pittsburgh School of Medicine report that they have successfully used gene therapy to block the pain response in an animal model of neuropathic pain, a type of chronic pain in people for which there are few effective treatments.

1 Jun 2007

Study suggests potential for a broadly-protective HIV vaccine

30 May 2007

Depression is a risk factor for osteoporosis

Evidence is accumulating that depression is a risk factor for osteoporosis, reports the June 2007 issue of Harvard Women's Health Watch.

30 May 2007

Significant breakthrough in the search for an effective malaria vaccine

One person dies of it every 30 seconds, it rivals HIV and tuberculosis as the world's most deadly infection and the vast majority of its victims are under five years old.

28 May 2007

Significant breakthrough in the search for an effective malaria vaccine

One person dies of it every 30 seconds, it rivals HIV and tuberculosis as the world's most deadly infection and the vast majority of its victims are under five years old.

24 May 2007

COX inhibitors may weaken protective qualities of estrogen therapy

Researchers from the University of Pennsylvania School of Medicine found in a database study of women heart patients that COX inhibitors such as traditional nonsteroidal anti-inflammatory drugs (NSAIDs) may undermine any purported protection against heart disease in participants taking estrogen therapy.

24 May 2007

Macrophages may have role blocking obesity

Macrophages - the scavenger cells of the body's immune system - are known as troublemakers for the role they play in obesity, but Stanford University School of Medicine researchers have found that the cells can also be saviors when it comes to metabolism.

22 May 2007

Researchers use gene therapy to restore sight in mice

University of Florida researchers used gene therapy to restore sight in mice with a form of hereditary blindness, a finding that has bearing on many of the most common blinding diseases.

22 May 2007