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Scientists uncover hints of a potential new cause of stomach cancer

For the first time, scientists have systematically analyzed somatic mutations in stomach lining tissue to unpick mutational processes, some of which can lead to cancer.

19 Mar 2025

Study reveals how B cells safeguard high-affinity antibodies

A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a vaccine or pathogen, B cells scramble to refine their defenses, rapidly mutating in hopes of generating the most effective antibodies.

19 Mar 2025

Research findings solve the paradox of how the immune system balances speed and precision

Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and expansion until they produce high-affinity B cells adapted to keep different pathogens in check.

19 Mar 2025

Clinical trial investigates osteoporosis medication for type 1 diabetes

City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the United States and a top research center for diabetes and other life-threatening illnesses, is leading a phase 1/2 clinical trial investigating an osteoporosis medication as a way to improve beta cell health in people with early type 1 diabetes.

19 Mar 2025

New tool visualizes immune response to abnormal DNA

A research led by Sergio P. Acebrón, Researcher Ikerbasque at the UPV/EHU, develops a key tool to visualize the immune response to abnormal DNA, opening new avenues for the treatment of diseases.

19 Mar 2025

Small intestine grows in response to pregnancy in mice

Researchers at the Francis Crick Institute have found that the small intestine grows in response to pregnancy in mice. This partially irreversible change may help mice support a pregnancy and prepare for a second.

19 Mar 2025

Earliest stages and possible new cause of stomach cancer revealed

For the first time, scientists have systematically analyzed somatic mutations in stomach lining tissue to unpick mutational processes, some of which can lead to cancer.

19 Mar 2025

Understanding the role of CD2AP in Alzheimer's disease

A groundbreaking peer-reviewed Thought Leaders Invited Review article in Brain Medicine (Genomic Press, New York) explores how CD2-associated protein (CD2AP) contributes to Alzheimer's disease (AD), one of the most devastating neurodegenerative disorders affecting millions worldwide.

19 Mar 2025

Researchers challenge the genetic paradigm of cancer

It's time for researchers to reconsider the current paradigm of cancer as a genetic disease, argued Sui Huang from the Institute for Systems Biology, USA, and colleagues in a new essay published March 18th in the open-access journal PLOS Biology.

19 Mar 2025

New discovery unravels mystery behind overactive immune responses

Autoimmune diseases, which are estimated to affect more than 15 million people in the U.S., occur when the body responds to immune-system false alarms, and infection-fighting first responders are sent out to attack threats that aren't there.

18 Mar 2025

Moffitt researchers discover new vaccine strategy for treating specific type of breast cancer

Moffitt Cancer Center researchers have discovered a promising new vaccine strategy for treating a specific type of breast cancer.

18 Mar 2025

Harnessing AI to combat rheumatoid arthritis

Fan Zhang, PhD, sees artificial intelligence as a pathway to finding an effective way to combat an intractable enemy: rheumatoid arthritis.

18 Mar 2025

FDA-approved drug for chronic kidney disease may help mitigate antibiotic resistance

Increased antibiotic use can lead, seemingly paradoxically, to more problematic infections, as the bacteria evolve to resist the treatment.

18 Mar 2025

Study sheds light on why women experience chronic pain more than men

A new study led by University of Calgary professor Dr. Tuan Trang, PhD, may help to explain why there is an over-representation of women experiencing chronic pain compared to men.

18 Mar 2025

UZH researchers develop technology to test 25 antibodies in a single mouse

New active ingredients such as antibodies are usually tested individually in laboratory animals. Researchers at UZH have now developed a technology that can be used to test around 25 antibodies simultaneously in a single mouse.

18 Mar 2025

AI-based neural network revolutionizes cancer treatment predictions

A first-of-its-kind artificial intelligence (AI)-based neural network can rapidly analyze and interpret millions of cells from a patient sample, predicting molecular changes in the tissue.

18 Mar 2025

Lymph node transfer proven effective for lymphedema after breast cancer surgery

A multicenter study led from Finland has shown that lymph node transfer is a viable treatment for the swelling in the affected limb, a condition known as lymphedema, after breast cancer surgery.

18 Mar 2025

Biomanufacturing platform offers a sustainable alternative to synthesizing peptide-based pharmaceuticals

To tackle the inequity in medication access, a societal issue especially in developing nations, a team of undergraduate student-researchers at the University of Ottawa has developed a new biomanufacturing platform called Phytogene.

18 Mar 2025

Beckman Coulter Life Sciences launches industry-first modular spectral flow cytometry solution

Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, and an Operating Company of Danaher Corporation, revolutionizes spectral flow cytometry with the industry’s first modular solution: the CytoFLEX mosaic Spectral Detection Module.

From Beckman Coulter Life Sciences - Flow Cytometry 18 Mar 2025