Central Nervous System News and Research

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New hope for people suffering from depression

There is new hope for people suffering from depression. Researchers have identified a compound, hydroxynorketamine (HNK), that may treat symptoms of depression just as effectively and rapidly as ketamine, without the unwanted side effects associated with the psychoactive drug, according to a study in the July issue of Anesthesiology, the official medical journal of the American Society of Anesthesiologists- (ASA-).

17 Jun 2014

Computer programming language automates "laboratory-on-a-chip", may reduce healthcare cost

A research team at the University of California, Riverside has created a computer programming language that will automate "laboratory-on-a-chip" technologies used in DNA sequencing, drug discovery, virus detection and other biomedical applications.

17 Jun 2014

New class of tumor-targeting agents can seek out dozens of solid tumors

Scientists at the University of Wisconsin Carbone Cancer Center (UWCCC) report that a new class of tumor-targeting agents can seek out and find dozens of solid tumors, even illuminating brain cancer stem cells that resist current treatments.

13 Jun 2014

Investigators isolate protein that is responsible for fungus' ability to cross blood-brain barrier

In a remarkable series of experiments on a fungus that causes cryptococcal meningitis, a deadly infection of the membranes that cover the spinal cord and brain, investigators at UC Davis have isolated a protein that appears to be responsible for the fungus' ability to cross from the bloodstream into the brain.

13 Jun 2014

Survivors of childhood cancers hospitalized more often many years after cancer treatment

Survivors of childhood cancers were hospitalized more often and for longer durations because of blood disorders and other problems, many years after cancer treatment was completed, compared with the general population, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

13 Jun 2014

Proteins causing daytime sleepiness also play crucial role in bone formation

Orexin proteins, which are blamed for spontaneous daytime sleepiness, also play a crucial role in bone formation, according to findings by UT Southwestern Medical Center researchers.

13 Jun 2014

electroCore's non-invasive vagus nerve stimulation therapy reduces cluster headache attacks

In a multi-center, randomized, trial across Europe, electroCore's non-invasive vagus nerve stimulation (nVNS) therapy was found to meet its primary endpoint of statistical significance in reducing the number of cluster headache attacks when compared with the standard of care.

10 Jun 2014

Chronic sleep loss can cause certain neurotoxic molecules to permeate into brain tissue

The longer the insomnia, junctions of cerebral blood vessels begin to degrade. In search of the answer to why do we sleep, research conducted at the Mexican Metropolitan Autonomous University (UAM) revealed that chronic sleep loss can cause certain neurotoxic molecules, which normally circulate in the blood, to be transported to the central nervous system and interfere with the function of neurons.

10 Jun 2014

Study defines how our ability to identify spatial acuity varies across the body

"Where does it hurt?" is the first question asked to any person in pain. A new UCL study defines for the first time how our ability to identify where it hurts, called "spatial acuity", varies across the body, being most sensitive at the forehead and fingertips.

9 Jun 2014

Study: The brain controls cellular process that leads to glaucoma

Findings from a new study published in Translational Vision Science & Technology show the brain, not the eye, controls the cellular process that leads to glaucoma. The results may help develop treatments for one of the world's leading causes of irreversible blindness, as well as contribute to the development of future therapies for preserving brain function in other age-related disorders like Alzheimer's.

6 Jun 2014

Healthy tissue grafted to brains of patients with Huntington's disease also develops signs of illness

A recent study published in Annals of Neurology reports that healthy human tissue grafted to the brains of patients with Huntington's disease in the hopes of treating the neurological disorder also developed signs of the illness, several years after the graft.

6 Jun 2014

ImStem successfully treats animal model of multiple sclerosis using hESC

ImStem Biotechnology, Inc. (ImStem) announced today it has successfully treated an animal model of multiple sclerosis (MS) using human embryonic stem cells (hESC) derived mesenchymal stem cells (MSCs), called hES-MSCs.

6 Jun 2014

$SAGE reports preliminary data from SAGE-547 Phase 1/2 clinical trial for super-refractory status epilepticus$

SAGE reports preliminary data from SAGE-547 Phase 1/2 clinical trial for super-refractory status epilepticus

SAGE Therapeutics, a biopharmaceutical company developing novel medicines to treat life-threatening, rare central nervous system (CNS) disorders, today announced preliminary data from its ongoing open-label Phase 1/2 clinical trial of SAGE-547, an allosteric modulator of GABAA receptors, in patients with super-refractory status epilepticus (SRSE).

5 Jun 2014

Nurse residency program receives recognition for consistent, high quality care

The nurse residency program at University of Louisville Hospital, a part of KentuckyOne Health, is one of 12 in the nation to receive recognition for consistent, high quality care.

4 Jun 2014

Neurobiologist Thomas Jessell to be honored with 2014 Gruber Neuroscience Prize

Thomas Jessell, PhD, the Claire Tow Professor of Motor Neuron Disorders in the Departments of Neuroscience and of Biochemistry and Molecular Biophysics at Columbia University, is the recipient of the 2014 Neuroscience Prize of The Gruber Foundation.

4 Jun 2014

Autifony Therapeutics awarded £2.2 million to progress first-in-class drug for tinnitus into Phase IIa study

Autifony Therapeutics Limited (“Autifony”), which is pioneering the development of novel pharmaceutical treatments for hearing disorders, today announced that it has been awarded funding of £2.2 million towards a Phase IIa clinical trial in tinnitus patients with its lead compound AUT00063, by the UK’s innovation agency, the Technology Strategy Board.

4 Jun 2014

P2Y12 and blood clotting: an interview with Dr. Jacobson, NIH

We already understand the many steps involved in blood clotting in great mechanistic detail. The process of blood vessels closing off in response to injury is necessary for preserving life, but blood platelets that are over-active, or activated inappropriately because of unstable plaque, can lead to heart attacks and strokes.

3 Jun 2014

Ezyme used as target for antidepressants may also provide way to cure prostate cancer

An international team of scientists including researchers at the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute and the University of Southern California found that an enzyme commonly used as a target for antidepressants may also promote prostate cancer growth.

2 Jun 2014

HCV reactivation may not worsen survival outcomes for lymphoma patients with HIV

More than a quarter of HIV+ patients are also infected with the Hepatitis C virus (HCV), which may complicate treatment and care decisions after a cancer diagnosis. The specifics of those complications haven't been well-researched in the past. Results from a new Fox Chase Cancer Center study on this patient population may start filling in that gap.

31 May 2014

$ASCO: DelMar presents interim data from VAL-083 clinical trial in refractory GBM$

ASCO: DelMar presents interim data from VAL-083 clinical trial in refractory GBM

DelMar Pharmaceuticals, Inc. announced the presentation of interim clinical data from the company's ongoing clinical trial with VAL-083 in refractory glioblastoma multiforme (GBM) during the Central Nervous System Tumor Session at the 50th Annual Meeting of the American Society of Clinical Oncology (ASCO), which is being held at the McCormick Place Convention Center in Chicago.

31 May 2014

Central Nervous System News and Research

New hope for people suffering from depression

Computer programming language automates "laboratory-on-a-chip", may reduce healthcare cost

New class of tumor-targeting agents can seek out dozens of solid tumors

Investigators isolate protein that is responsible for fungus' ability to cross blood-brain barrier

Survivors of childhood cancers hospitalized more often many years after cancer treatment

Proteins causing daytime sleepiness also play crucial role in bone formation

electroCore's non-invasive vagus nerve stimulation therapy reduces cluster headache attacks

Chronic sleep loss can cause certain neurotoxic molecules to permeate into brain tissue

Study defines how our ability to identify spatial acuity varies across the body

Study: The brain controls cellular process that leads to glaucoma

Healthy tissue grafted to brains of patients with Huntington's disease also develops signs of illness

ImStem successfully treats animal model of multiple sclerosis using hESC

SAGE reports preliminary data from SAGE-547 Phase 1/2 clinical trial for super-refractory status epilepticus

Nurse residency program receives recognition for consistent, high quality care

Neurobiologist Thomas Jessell to be honored with 2014 Gruber Neuroscience Prize

Autifony Therapeutics awarded £2.2 million to progress first-in-class drug for tinnitus into Phase IIa study

P2Y12 and blood clotting: an interview with Dr. Jacobson, NIH

Ezyme used as target for antidepressants may also provide way to cure prostate cancer

HCV reactivation may not worsen survival outcomes for lymphoma patients with HIV

ASCO: DelMar presents interim data from VAL-083 clinical trial in refractory GBM

Event guide: The 7th CNS Drug Delivery Summit eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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