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Drug combination highly effective in children with standard- and high-risk acute promyelocytic leukemia

A clinical trial has found that the combination of all-trans retinoic acid, which is a metabolite of vitamin A, and arsenic trioxide is highly effective in children with standard- and high-risk acute promyelocytic leukemia, or APL.

11 Nov 2021

Finnish study highlights the need for mRNA COVID vaccine booster shots

A register-based cohort study of the effectiveness of COVID-19 vaccines was performed to help decision-making on providing booster doses to social and healthcare workers (HCWs) like nurses, physicians, dentists, and other professionals in Finland. In addition, it estimated the vaccine effectiveness after the second dose. This study is published on the medRxiv* preprint server.

9 Nov 2021

Favourable meta-analysis of inhaled corticosteroids in COVID-19 outpatients

Two open-label randomized controlled trials (RCTs) on the use of inhaled corticosteroids such as budesonide in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected patients have helped garner attention towards inhaled corticosteroids as a safe and inexpensive treatment method in non-hospitalized SARS-CoV-2 patients.

9 Nov 2021

Psychiatric drug prevents some of the most serious complications of COVID-19, study finds

Leonard Imbula of the Healthy Mind Lab at Washington University School of Medicine in St. Louis holds a bottle of fluvoxamine, a psychiatric drug that has been shown, in a pair of studies conducted on two continents, to be an effective treatment for people sick with COVID-19.

9 Nov 2021

Oral SARS-CoV-2 Mpro inhibitor for therapeutic use

A new study describes a new small molecule compound that has shown impressive safety, tolerability, and bioavailability against SARS-CoV-2.

7 Nov 2021

Arginine treatment enhances effectiveness of radiation therapy in cancer patients with brain metastases

Treatment with arginine, one of the amino-acid building blocks of proteins, enhanced the effectiveness of radiation therapy in cancer patients with brain metastases, in a proof-of-concept, randomized clinical trial from investigators at Weill Cornell Medicine and Angel H. Roffo Cancer Institute.

7 Nov 2021

Oral drug works just as well as conventional therapy for anemia in patients with kidney disease

Anemia is a common and sometimes debilitating problem among patients with chronic kidney disease (CKD). Anemia can occur when the kidneys become damaged, limiting the production of erythropoietin (EPO) - a hormone that signals to the body to make red blood cells.

7 Nov 2021

Results of high-impact clinical trials could affect kidney-related medical care

The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented online at ASN Kidney Week 2021 November 4–November 7.

7 Nov 2021

Study uncovers a process in cells that may limit infectivity of SARS-CoV-2

Scientists at the National Institutes of Health have found that a process in cells may limit infectivity of SARS-CoV-2, and that mutations in the alpha and delta variants overcome this effect, potentially boosting the virus's ability to spread.

6 Nov 2021

MHRA approves first oral antiviral for the treatment of COVID-19

The antiviral Lagevrio (molnupiravir) is safe and effective at reducing the risk of hospitalization and death in people with mild to moderate COVID-19 who are at increased risk of developing severe disease, the Medicines and Healthcare products Regulatory Agency announced today.

4 Nov 2021

Study: Ultra-low rituximab dose maintains low disease activity for most RA patients

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that in one study, the majority of rheumatoid arthritis patients on an ultra-low dose of the drug rituximab maintained low disease activity for up to four years, and rarely needed to switch to other biologic drugs or glucocorticoids to control their disease.

2 Nov 2021

Scientists discover key component of cellular malfunction that contributes to growth of tumors

Scientists have homed in on a crucial step within the sequence of chemical reactions that govern regulation of cell division, proliferation and death, and whose malfunction contributes to the growth of tumors.

2 Nov 2021

Novel drug improves management of ulcerative colitis

A new drug improved management of ulcerative colitis, according to a study published in the New England Journal of Medicine.

2 Nov 2021

$15 million gift to fund undergraduate programs and graduate student fellowships in life sciences

A decades-long friendship and a shared passion for basic science has inspired a $15 million gift to the Division of Biology & Biomedical Sciences (DBBS) at Washington University in St. Louis to fund undergraduate programs and graduate student fellowships in the life sciences.

30 Oct 2021

Researchers explore whether salivary glands infected with SARS-CoV-2 can diminish long-term immunity

University of Utah Health scientists are leading an effort to determine if salivary glands infected with the virus that causes COVID-19 could diminish a person’s long-term immunity to the disease after being immunized or after recovering from the illness.

30 Oct 2021

Two new studies show how to enhance effectiveness of cancer immunotherapy

Two new studies revealed that anti-PD-1 immunotherapy given before surgery was safe and effective for patients with oral-cavity squamous cell carcinoma (OCSCC) and identified potential molecular biomarkers in the blood and tumors of patients that would show how likely it is that someone would respond to immunotherapy.

30 Oct 2021

Oral News and Research

Drug combination highly effective in children with standard- and high-risk acute promyelocytic leukemia

Finnish study highlights the need for mRNA COVID vaccine booster shots

Favourable meta-analysis of inhaled corticosteroids in COVID-19 outpatients

Psychiatric drug prevents some of the most serious complications of COVID-19, study finds

Oral SARS-CoV-2 Mpro inhibitor for therapeutic use

Arginine treatment enhances effectiveness of radiation therapy in cancer patients with brain metastases

Oral drug works just as well as conventional therapy for anemia in patients with kidney disease

Results of high-impact clinical trials could affect kidney-related medical care

Study uncovers a process in cells that may limit infectivity of SARS-CoV-2

MHRA approves first oral antiviral for the treatment of COVID-19

Study: Ultra-low rituximab dose maintains low disease activity for most RA patients

Scientists discover key component of cellular malfunction that contributes to growth of tumors

Novel drug improves management of ulcerative colitis

$15 million gift to fund undergraduate programs and graduate student fellowships in life sciences

Researchers explore whether salivary glands infected with SARS-CoV-2 can diminish long-term immunity

Two new studies show how to enhance effectiveness of cancer immunotherapy

If Congress adds dental coverage to Medicare, should all seniors get it?

Texas abortion law gets speedy high-court hearing Monday

87% of the patients still favor root canal treatment for badly damaged teeth

KHN’s ‘What the Health?’: Biden social-spending ‘framework’ pulls back on key health pledges

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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