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Taking NSAIDs with other drugs can increase risk of upper GI bleeding, study finds

Nonsteroidal anti-inflammatory drugs (NSAIDs) - such as ibuprofen and aspirin - increase one's risk of upper gastrointestinal bleeding. When taken in combination with other drugs, this risk is significantly higher, according to new research appearing in the October issue of Gastroenterology, the official journal of the American Gastroenterological Association.

3 Oct 2014

Early review: Open payments database not so open

The new federal website, which was created to provide information about financial links between physicians and the drug industry, is not user-friendly, notes The Associated Press. Meanwhile, The Wall Street Journal digs into the data to see what it shows about the ties between medical professionals and the drug industry.

3 Oct 2014

Study uncovers new pathway for treating high blood pressure, heart failure

New research by scientists at the University of Maryland School of Medicine and the Ottawa Heart Institute has uncovered a new pathway by which the brain uses an unusual steroid to control blood pressure.

3 Oct 2014

NKT Therapeutics' NKTT120 receives FDA Fast Track designation for treatment of sickle cell disease

NKT Therapeutics today announced that the U.S. Food and Drug Administration has granted Fast Track designation to NKTT120, the company's lead therapeutic being developed for the treatment of sickle cell disease.

3 Oct 2014

Study: Benzodiazepine sedatives may increase death risk in patients receiving mechanical ventilation

Sedation is frequently required for mechanically ventilated intensive care unit (ICU) patients to reduce anxiety, provide comfort, and assist in providing optimal respiratory support.

1 Oct 2014

Ganymed, BioNTech AG open new headquarters and research facility in Germany

BioNTech AG and Ganymed Pharmaceuticals AG, two premier German biotechology companies, announced today the joint- opening of a new approx. 10,000 square-meters (108,000 square-feet) headquarters and research facility.

1 Oct 2014

Open payments database debuts, detailing financial connections between physicians and drug makers

Consumer advocates have pushed for years for this kind of government database in an effort to protect against physicians' conflicts of interest, to safeguard patient care and to prevent unnecessary costs to public health programs.

1 Oct 2014

GSK awards milestone payment to Isis Pharmaceuticals to develop ISIS-GSK4Rx for ocular disease

Isis Pharmaceuticals, Inc. announced today that it has earned a $1.5 million milestone payment from GSK related to the advancement of the program to develop ISIS-GSK4Rx to treat an undisclosed ocular disease.

1 Oct 2014

Doctors, hospitals went digital, but still can't share records

After spending billions to switch from paper to digital records -- much of it taxpayer subsidized through the economic stimulus package -- providers say the systems often do not share information with competitors.

1 Oct 2014

Agingcare.com introduces Prescription Drug Assistance Locator tool

Paying for prescription medications just got easier for families who frequent AgingCare.com, the go-to destination for family caregivers.

1 Oct 2014

Columbia Laboratories' subsidiary to unveil ROADMAP to Clinical Trials platform at CPhI/ICSE event

Columbia Laboratories, Inc., today announced that its subsidiary, Molecular Profiles Ltd., is set to unveil the ROADMAP to Clinical Trials platform at the annual CPhI/ICSE Worldwide event in Paris next week, which aims to support companies with the rapid development of both standard and complex drug products.

1 Oct 2014

Viewpoints: Mergers causing health costs to rise; reauthorize CHIP; Obamacare's influence on politics

Health care costs are going up, and there's a lot of debate about why. Is it the high cost of drugs or our aging population?

1 Oct 2014

Viewpoints: Shop around for health coverage; 'gaming' Obamacare; FDA and painkillers

My colleagues Margot Sanger-Katz and Amanda Cox wrote recently that shopping around for the best price can be crucial for people renewing their coverage on the health insurance exchanges this fall.

1 Oct 2014

Mission Pharmacal adds Ovace Plus Lotion to its range of product offerings

Itch. Scratch. Repeat. Irritating skin conditions, such as seborrheic dermatitis (SD), can create a distracting, uncomfortable vicious circle for those affected.

1 Oct 2014

Sanofi, Regeneron report positive Phase 2 study of dupilumab in patients with CSwNP

Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) and Sanofi (EURONEXT: SAN and NYSE: SNY) today announced that a Phase 2a proof-of-concept study of dupilumab, an investigational therapy that blocks IL-4 and IL-13 signaling, met all primary and secondary endpoints in patients with moderate-to-severe chronic sinusitis with nasal polyps (CSwNP) who did not respond to intranasal corticosteroids.

30 Sep 2014

U-M researchers describe new approach to discovering potential cancer treatments

Researchers at the University of Michigan have described a new approach to discovering potential cancer treatments that requires a fraction of the time needed for more traditional methods.

30 Sep 2014

AZD9291 shows median progression-free survival in patients with EGFRm T790M+ advanced NSCLC

Updated data from the ongoing AURA study of AZD9291 shows encouraging, although still immature, median progression free survival of 9.6 months (95% CI 8.3 to NC) in patients with epidermal growth factor receptor mutation positive (EGFRm) T790M+ advanced non-small cell lung cancer (NSCLC) who had disease progression following treatment with an EGFR tyrosine kinase inhibitor (EGFR TKI).

30 Sep 2014

CNIO researchers discover new specific marker for cancer stem cells

Tumours are mosaics of cells that are morphologically and molecularly very different. In this cellular heterogeneity, it is calculated that only 1-2% of the tumour mass is made up of cancer stem cells, which over the past years have been suggested to be responsible for the origin of cancer and for the resistance to conventional chemical therapies.

30 Sep 2014

Par Pharmaceutical starts shipping generic version of Exforge

Par Pharmaceutical Companies, Inc. today announced that it has begun shipping all four strengths of amlodipine and valsartan tablets, the generic version of Novartis' Exforge. Par received final approval from the U.S. Food and Drug Administration for its Abbreviated New Drug Application for amlodipine and valsartan and was granted 180 days of marketing exclusivity.

30 Sep 2014

Researchers uncover molecular interaction between key proteins in cell division

Researchers from Guillermo Montoya's team at the Spanish National Cancer Research Centre (CNIO), in collaboration with Isabelle Vernos' Group from the Centre for Genomic Regulation (CRG), have uncovered the molecular interaction between TACC3 and chTOG, key proteins in forming the internal cellular framework that enables and sustains cell division.

30 Sep 2014

Drugs News and Research

Taking NSAIDs with other drugs can increase risk of upper GI bleeding, study finds

Early review: Open payments database not so open

Study uncovers new pathway for treating high blood pressure, heart failure

NKT Therapeutics' NKTT120 receives FDA Fast Track designation for treatment of sickle cell disease

Study: Benzodiazepine sedatives may increase death risk in patients receiving mechanical ventilation

Ganymed, BioNTech AG open new headquarters and research facility in Germany

Open payments database debuts, detailing financial connections between physicians and drug makers

GSK awards milestone payment to Isis Pharmaceuticals to develop ISIS-GSK4Rx for ocular disease

Doctors, hospitals went digital, but still can't share records

Agingcare.com introduces Prescription Drug Assistance Locator tool

Columbia Laboratories' subsidiary to unveil ROADMAP to Clinical Trials platform at CPhI/ICSE event

Viewpoints: Mergers causing health costs to rise; reauthorize CHIP; Obamacare's influence on politics

Viewpoints: Shop around for health coverage; 'gaming' Obamacare; FDA and painkillers

Mission Pharmacal adds Ovace Plus Lotion to its range of product offerings

Sanofi, Regeneron report positive Phase 2 study of dupilumab in patients with CSwNP

U-M researchers describe new approach to discovering potential cancer treatments

AZD9291 shows median progression-free survival in patients with EGFRm T790M+ advanced NSCLC

CNIO researchers discover new specific marker for cancer stem cells

Par Pharmaceutical starts shipping generic version of Exforge

Researchers uncover molecular interaction between key proteins in cell division

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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