Central Nervous System News and Research

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Angiochem presents data on ANG1005 paclitaxel-peptide drug conjugate at 50th ASCO annual meeting

Angiochem, a clinical stage biotechnology company developing drugs that are uniquely capable of crossing the blood-brain barrier (BBB), today announced the presentation of data for its lead drug candidate, ANG1005, a novel paclitaxel-peptide drug conjugate, at the American Society of Clinical Oncology 50th Annual Meeting in Chicago, IL.

31 May 2014

Patients with AIDS-related lymphomas may face increased risk of CNSi

Patients with AIDS-related lymphomas (ARL) may face an increased risk of central nervous system involvement (CNSi) compared to other lymphomas. The effect of CNSi on survival outcomes, however, hasn't been thoroughly examined until now.

31 May 2014

Newron Pharmaceuticals submits safinamide NDA to FDA

Newron Pharmaceuticals S.p.A. ("Newron"), a research and development company focused on novel CNS and pain therapies, and its partner Zambon S.p.A., an international pharmaceutical company strongly committed to the CNS therapeutic area with a long experience in respiratory disease therapies, woman care and primary care, announce that the New Drug Application (NDA) for safinamide was submitted today to the US Food and Drug Administration (FDA).

30 May 2014

Lyme disease bacteria older than human race, says study

Lyme disease is a stealthy, often misdiagnosed disease that was only recognized about 40 years ago, but new discoveries of ticks fossilized in amber show that the bacteria which cause it may have been lurking around for 15 million years - long before any humans walked on Earth.

30 May 2014

Synexus starts new state of art clinical trial centre in Bochum, Germany

On 28th May, 2014, Synexus officially opened a new state of the art clinical trial centre in Bochum, Germany.

From AES - Accelerated Enrollment Solutions 29 May 2014

Stem cells in outer blood vessel wall appear to involve in brain reaction following stroke

Two years ago, a new type of stem cell was discovered in the brain that has the capacity to form new cells.

28 May 2014

Study suggests that stiff arteries alone enough to cause high BP in "virtual human"

High blood pressure is highly age-related and affects more than 1 billion people worldwide. But doctors can't fully explain the cause of 90 per cent of all cases. A computer model of a "virtual human" suggests that stiff arteries alone are enough to cause high blood pressure.

27 May 2014

Erlotinib, gefitinib have similar efficacy in NSCLC patients with EGFR mutation

Disease progression-free survival is similar for patients with non-small-cell lung cancer and epidermal growth factor receptor mutations whether they receive erlotinib or gefitinib, show the results of a South Korean study.

21 May 2014

New compound restores learning, memory and other symptoms of AD in mice

A molecular compound developed by Saint Louis University scientists restored learning, memory and appropriate behavior in a mouse model of Alzheimer's disease, according to findings in the May issue of the Journal of Alzheimer's Disease.

21 May 2014

Serious complications due to anesthesia during childbirth are very rare

Expectant mothers concerned about receiving an epidural, spinal or general anesthesia during childbirth can breathe a little easier. According to a study published in the June issue of Anesthesiology, the official medical journal of the American Society of Anesthesiologists, serious complications due to anesthesia during childbirth are very rare, occurring in one out of every 3,000 deliveries.

21 May 2014

Edison Pharmaceuticals' EPI-743 granted orphan designation for Leigh syndrome in Japan

Edison Pharmaceuticals has announced that the Japanese Ministry of Health, Labor and Welfare (MHLW) has granted Orphan Designation to EPI-743 for the treatment of Leigh syndrome.

21 May 2014

FDA approves Takeda's Entyvio for severe active ulcerative colitis and Crohn's disease

Takeda Pharmaceutical Company Limited and its wholly-owned subsidiary, Takeda Pharmaceuticals U.S.A., Inc., has announced that the United States (U.S.) Food and Drug Administration (FDA) simultaneously approved a new biologic therapy, Entyvio™ (vedolizumab), for the treatment of adults with moderately to severely active ulcerative colitis (UC) and Crohn's disease (CD).

21 May 2014

Abbott signs definitive agreement to acquire CFR Pharmaceuticals

Abbott today announced a definitive agreement to acquire Latin American pharmaceutical company CFR Pharmaceuticals, more than doubling its Latin American branded generics pharmaceutical presence and further expanding Abbott's presence in fast-growing markets.

16 May 2014

CNS stimulant no more effective than placebo for alleviating lung cancer fatigue

Patients with advanced non-small-cell lung cancer who received the central nervous system stimulant modafinil reported no greater reduction in fatigue than patients given placebo, show study results.

13 May 2014

New implantable cuff with 24 electrodes helps reduce high blood pressure

Freiburg researchers develop new method for lowering high blood pressure without side effects. High blood pressure is the greatest health risk worldwide behind smoking and alcohol consumption.

12 May 2014

Shift switches pain sensor from cold-sensitive to hot-sensitive

Ice cream lovers and hot tea drinkers with sensitive teeth could one day have a reason to celebrate a new finding from Duke University researchers. The scientists have found a very small change in a single protein that turns a cold-sensitive receptor into one that senses heat.

9 May 2014

New study associates sex difference in brain with MS

A newly identified difference between the brains of women and men with multiple sclerosis (MS) may help explain why so many more women than men get the disease, researchers at Washington University School of Medicine in St. Louis report.

9 May 2014

Pharmaceutical Executive Magazine names COPAXONE therapy as 2014 "Brand of The Year"

Teva Pharmaceutical Industries Ltd., today announced that COPAXONE (glatiramer acetate injection), the #1 global therapy for relapsing multiple sclerosis, has been named the 2014 "Brand of The Year" by Pharmaceutical Executive Magazine, a leading print and online publication for the biopharmaceutical industry.

9 May 2014

Cellectricon, Neusentis to host webinar on phenotypic screening approaches in pain research

Cellectricon, a leading provider of advanced cell-based screening technologies and services, will co-host a webinar with Neusentis, describing the use of native cells to develop an assay with improved physiological relevance over traditional approaches in pain drug discovery research.

From Cellectricon 8 May 2014

Naurex's two lead antidepressant programs achieve major milestones

Naurex Inc., a privately held biopharmaceutical company leveraging its unique platform to develop novel drugs for diseases of the central nervous system (CNS), today announced that its two lead antidepressant programs achieved major milestones.

6 May 2014

Central Nervous System News and Research

Angiochem presents data on ANG1005 paclitaxel-peptide drug conjugate at 50th ASCO annual meeting

Patients with AIDS-related lymphomas may face increased risk of CNSi

Newron Pharmaceuticals submits safinamide NDA to FDA

Lyme disease bacteria older than human race, says study

Synexus starts new state of art clinical trial centre in Bochum, Germany

Stem cells in outer blood vessel wall appear to involve in brain reaction following stroke

Study suggests that stiff arteries alone enough to cause high BP in "virtual human"

Erlotinib, gefitinib have similar efficacy in NSCLC patients with EGFR mutation

New compound restores learning, memory and other symptoms of AD in mice

Serious complications due to anesthesia during childbirth are very rare

Edison Pharmaceuticals' EPI-743 granted orphan designation for Leigh syndrome in Japan

FDA approves Takeda's Entyvio for severe active ulcerative colitis and Crohn's disease

Abbott signs definitive agreement to acquire CFR Pharmaceuticals

CNS stimulant no more effective than placebo for alleviating lung cancer fatigue

New implantable cuff with 24 electrodes helps reduce high blood pressure

Shift switches pain sensor from cold-sensitive to hot-sensitive

New study associates sex difference in brain with MS

Pharmaceutical Executive Magazine names COPAXONE therapy as 2014 "Brand of The Year"

Cellectricon, Neusentis to host webinar on phenotypic screening approaches in pain research

Naurex's two lead antidepressant programs achieve major milestones

Event guide: The 7th CNS Drug Delivery Summit eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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