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Researchers discover protein that may open door to new method of treating type 2 diabetes

The STK25 protein contributes to cell growth. Researchers at Sahlgrenska Academy have discovered that the protein also affects metabolism, demonstrating that elevated levels accelerate the progress of diabetes in mice.

3 Sep 2014

Bypassing politics, insurers pay for end of life talks

These doctor-patient conversations had been labeled "death panels" by opponents of the Affordable Care Act. Meanwhile, in a bid to reduce backlogs, Medicare offers a deal to hospitals to pay 68 percent of short-term stay medical claims that were rejected by outside auditors.

3 Sep 2014

XBiotech reports interim results from Phase III study for anti-cancer agent Xilonix

XBiotech announced today interim results from its fast-tracked Phase III study being conducted in the US for its anti-cancer agent Xilonix.

2 Sep 2014

Nomination signals new approach to drug abuse policy

The nomination of Michael Botticelli to head the Office of National Drug Control Policy symbolizes the shift toward dealing with drug use as a public health rather than as a criminal justice issue, writes The Washington Post. Reuters looks at how opioid abuse fears keep cancer patients from getting pain relief.

2 Sep 2014

MEI Pharma completes patient enrollment in Pracinostat Phase II trial for treatment of MDS

MEI Pharma, Inc., an oncology company focused on the clinical development of novel therapies for cancer, announced today that it has completed enrollment in a randomized Phase II clinical trial of its lead investigational drug candidate Pracinostat in combination with azacitidine in patients with previously untreated intermediate-2 or high-risk myelodysplastic syndrome (MDS).

2 Sep 2014

VentiRx's motolimod receives FDA Fast Track designation for ovarian cancer treatment

VentiRx Pharmaceuticals, Inc., a clinical stage biopharmaceutical company committed to the development and commercialization of novel Toll-like receptor 8 (TLR8) immunotherapies, today announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation to the investigation of motolimod (VTX-2337) when administered in combination with pegylated liposomal doxorubicin (PLD) for the treatment of women with ovarian cancer whose disease has progressed on or recurred after platinum-based chemotherapy.

2 Sep 2014

Synthetic announces positive results from final preclinical toxicology study of SYN-004

Synthetic Biologics, Inc., a developer of novel anti-infective biologic and drug candidates targeting specific pathogens that cause serious infections and diseases, announced today positive results from its final preclinical toxicology study of SYN-004.

2 Sep 2014

Concordia's subsidiary signs collaboration deal with Orphan Canada for PHOTOFRIN

Concordia Healthcare Corp., a diverse healthcare company focused on legacy pharmaceutical products, orphan drugs, and medical devices for the diabetic population, today announced that its subsidiary, Pinnacle Biologics, Inc., a biopharmaceutical research and development company specializing in rare diseases, has signed a collaboration agreement for PHOTOFRIN® with Orphan Canada, a Toronto-based specialty pharmaceutical company that in‐licenses therapies for rare disorders and specialty medicines within Canada.

2 Sep 2014

American scientists develop another groundbreaking click concept: SuFEx

The coupling of molecular building blocks nearly as easy as “snapping” them together can be realized by means of the “click chemistry” tool kit. American scientists have now introduced another achievement for the click concept in the journal Angewandte Chemie: the sulfur fluoride exchange reaction (SuFEx) can be used to form robust inorganic bridges between carbon centers and opens up a fully unexplored area of chemistry with countless new molecules that could form the basis for new drugs, diagnostics, plastics, “intelligent” materials, and many other products.

2 Sep 2014

New vaccine in bid to move away from needles and syringes to skin delivery procedures

Drug delivery technologies that improve access and overall efficacy are becoming an essential part of the entire drug development process.

2 Sep 2014

Family dinners may help protect teens from cyberbullying, also be beneficial for mental health

Bottom Line: Cyberbullying was associated with mental health and substance use problems in adolescents but family dinners may help protect teens from the consequences of cyberbullying and also be beneficial for their mental health.

2 Sep 2014

Drugs plus biofeedback show promise for dysfunctional voiding

Research shows that the use of α1-blockers in combination with uroflowmetry biofeedback is more effective than either treatment alone for improving urinary symptoms and quality of life in women with dysfunctional voiding and recurrent urinary tract infection.

1 Sep 2014

New polypill increases adherence to treatment following myocardial infarction

A new polypill increases adherence to treatment following a myocardial infarction (MI), according to results from the FOCUS Study presented for the first time at ESC Congress 2014 today by principal investigator Dr Valentin Fuster, director of Mount Sinai Heart in New York, US.

1 Sep 2014

'Good' cholesterol turns 'bad' by sugar-derived substance

Scientists at the University of Warwick have discovered that 'good' cholesterol is turned 'bad' by a sugar-derived substance.

1 Sep 2014

Scientists develop synthetic amino acid that can impact 3D structure of bioactive peptides

One of the greatest challenges in modern medicine is developing drugs that are highly effective against a target, but with minimal toxicity and side-effects to the patient. Such properties are directly related to the 3D structure of the drug molecule.

1 Sep 2014

Measuring coronary artery blockage in heart attack patients can help avoid surgery

A method for measuring coronary artery blockage in heart attack patients can help more than one fifth of them avoid stents or surgery, according to a British study presented at the ESC Congress 2014 today.

1 Sep 2014

Antihypertensive therapy decreases risk of mortality, CV events, strokes in older adults

Antihypertensive therapy reduces the risk of cardiovascular (CV) events, strokes and mortality in hypertensive older adults, according to research presented at ESC Congress 2014 today by Dr Maciej Ostrowski from Poland.

1 Sep 2014

Wockhardt receives coveted QIDP status from FDA for WCK 771 and WCK 2349 drugs

Wockhardt Limited today announces a major boost to the New Drug Discovery program in Anti-Infective research when two of its drugs, WCK 771 and WCK 2349, received the coveted Qualified Infectious Disease Product (QIDP) status from U.S. Food & Drug Administration.

1 Sep 2014

Novel document on ventricular arrhythmias published in EP Europace

The first expert consensus on ventricular arrhythmias is published today. The novel document compiles current evidence on the diagnosis and management of ventricular arrhythmias and was agreed by international experts from three continents.

30 Aug 2014

Investigational LCZ696 drug: A real breakthrough for patients with heart failure

An investigational new heart failure drug could be poised to change the face of cardiology based on Hot Line results presented today at ESC Congress 2014.

30 Aug 2014

Drugs News and Research

Researchers discover protein that may open door to new method of treating type 2 diabetes

Bypassing politics, insurers pay for end of life talks

XBiotech reports interim results from Phase III study for anti-cancer agent Xilonix

Nomination signals new approach to drug abuse policy

MEI Pharma completes patient enrollment in Pracinostat Phase II trial for treatment of MDS

VentiRx's motolimod receives FDA Fast Track designation for ovarian cancer treatment

Synthetic announces positive results from final preclinical toxicology study of SYN-004

Concordia's subsidiary signs collaboration deal with Orphan Canada for PHOTOFRIN

American scientists develop another groundbreaking click concept: SuFEx

New vaccine in bid to move away from needles and syringes to skin delivery procedures

Family dinners may help protect teens from cyberbullying, also be beneficial for mental health

Drugs plus biofeedback show promise for dysfunctional voiding

New polypill increases adherence to treatment following myocardial infarction

'Good' cholesterol turns 'bad' by sugar-derived substance

Scientists develop synthetic amino acid that can impact 3D structure of bioactive peptides

Measuring coronary artery blockage in heart attack patients can help avoid surgery

Antihypertensive therapy decreases risk of mortality, CV events, strokes in older adults

Wockhardt receives coveted QIDP status from FDA for WCK 771 and WCK 2349 drugs

Novel document on ventricular arrhythmias published in EP Europace

Investigational LCZ696 drug: A real breakthrough for patients with heart failure

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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