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New collaborative fundraising effort focuses on AYA cancer

Leaders from Case Western Reserve University and University Hospitals this evening announced a new collaborative fundraising effort focused on Adolescent and Young Adult (AYA) cancer.

2 Jul 2014

New gene therapy for Acute Intermittent Porphyria

Angeles suffers from a severe and rare genetic disease called Acute Intermittent Porphyria (AIP). This means, one of her genes restrains her liver to produce a specific protein needed for the metabolism of the blood. During an AIP attack Angeles usually feels intense abdominal pain, and her mental status changes. Women live at an increased risk to trigger the symptoms, because porphyria is related to the menstrual cycle.

2 Jul 2014

Australian immunologists uncover additional role for antibody-making 'B cells'

A discovery by Australian immunologists, uncovering an additional role for antibody-making 'B cells', is considered important enough by the American Association of Immunologists to rank it among the top 10% of articles in the latest issue of The Journal of Immunology, off the press today.

2 Jul 2014

CHOP study: Children with specific gene variants may require higher doses of pain-control drugs

In the first genome-wide analysis of postsurgical pain in children, pediatric researchers identified variations in genes that affect a child's need for pain-control drugs. The findings suggest that at some point physicians may calibrate pain-medication dosages according to a child's individual genetic makeup.

2 Jul 2014

Researchers identify new biomarker that predicts effectiveness of glioblastoma treatment

Researchers at the University of California, San Diego School of Medicine have identified a new biomarker that predicts whether glioblastoma - the most common form of primary brain cancer - will respond to chemotherapy. The findings are published in the July print issue of Oncotarget.

2 Jul 2014

Drug everolimus fails to improve overall survival in advanced liver cancer patients

Despite strong preclinical data, the drug everolimus failed to improve overall survival in patients with advanced liver cancer, compared to placebo, according to a study in the July 2 issue of JAMA.

2 Jul 2014

More music therapists needed in psychiatric health care, says researcher

Music can help those without the means to express themselves to communicate. There is a need for more music therapists in psychiatric health care, says researcher Karin Mössler at Uni Research in Bergen, Norway.

1 Jul 2014

Aspirin, smoking influence aging processes of female genome connected to colorectal cancer

The risk of developing cancer increases with age. Factors like smoking and regular aspirin use also affect the risk of cancer - although in the opposite sense. Researchers from the University of Basel were now able to show that aspirin use and smoking both influence aging processes of the female genome that are connected to colorectal cancer.

1 Jul 2014

Proton beam therapy improves head and neck cancers free survival compared to IMRT

A new study by radiation oncologists at Mayo Clinic comparing the world's literature on outcomes of proton beam therapy in the treatment of a variety of advanced head and neck cancers of the skull base compared to intensity modulated radiation therapy (IMRT) has found that proton beam therapy significantly improved disease free survival and tumor control when compared to IMRT.

1 Jul 2014

Elderly mRCC patients should not be excluded from targeted therapy option

Advanced age is not a reason to preclude patients from receiving vascular endothelial growth factor-targeted therapy for metastatic renal cell carcinoma, show study findings from a mixed-age patient population.

1 Jul 2014

Partial nephrectomy predicts survival among metastatic RCC patients

Cytoreductive nephrectomy predicts improved survival among patients with metastatic renal cell carcinoma and synchronous metastases who have received first-line treatment with sunitinib, indicate study findings.

1 Jul 2014

LINX Reflux Management System safe for patients suffering from GERD, shows new data

Torax Medical today announced the release of new data from two leading U.S. medical centers that further establishes the LINX Reflux Management System as a safe and effective procedure for patients suffering from gastroesophageal reflux disease (GERD).

1 Jul 2014

State highlights: Caring for Texans injured on-the-job; heroin deaths in Md.; pertussis in Calif.

In formerly depressed South Texas, gas flares from the fracking boom can be seen from outer space. While Texas has a Division of Workers' Compensation, it is the only state that doesn't require any private employer to carry workers' compensation insurance or a private equivalent, so more than 500,000 people have no occupational benefits when they get injured at work. That means they often rely on charities or taxpayers to pay for their care (Root, 6/29)

1 Jul 2014

CTI completes recruitment in PERSIST-1 clinical trial of pacritinib for treatment of myelofibrosis

CTI BioPharma Corp. announced today that it has completed recruitment in the PERSIST-1 pivotal Phase 3 clinical trial of pacritinib, a novel oral JAK2/FLT3 inhibitor that is being evaluated for the treatment of myelofibrosis.

From Baxter International Inc. 1 Jul 2014

HIV-positive people with early-stage cancer less likely to get cancer treatment

HIV-infected people diagnosed with cancer are two to four times more likely to go untreated for their cancer compared to uninfected cancer patients, according to a new, large retrospective study from researchers in Penn Medicine's Abramson Cancer Center and the National Cancer Institute (NCI) published online ahead of print in the Journal of Clinical Oncology.

1 Jul 2014

New approach may help develop more effective immunotherapy for metastatic melanoma

A new approach demonstrated that the recognition of unique cancer mutations appeared to be responsible for complete cancer regressions in two metastatic melanoma patients treated with a type of immunotherapy called adoptive T-cell therapy.

1 Jul 2014

Researchers develop new way to identify potential therapeutic targets for drug resistant melanoma

Moffitt Cancer Center researchers developed a new way to identify possible therapeutic targets for patients with drug resistant melanoma. It involves using liquid chromatography-multiple reaction monitoring mass spectrometry to measure biomarkers or molecules in blood and tissue that indicates cancer is present. These measurements can help researchers determine if a patient is responding to treatment.

1 Jul 2014

Research could help to reduce health care charges

Recently published findings in Annals of Internal Medicine by Steven Lipshultz, M.D., Wayne State University professor and chair of pediatrics and pediatrician-in-chief at the Children's Hospital of Michigan, part of the Detroit Medical Center, and colleagues could help to reduce health care charges while also protecting childhood cancer survivors from heart ailments caused by drug therapy.

1 Jul 2014

Researchers find unique cell type that can protect against uveitis

Researchers at the National Eye Institute (NEI) have found a unique cell type that, in tests on mice, can protect against uveitis—a group of inflammatory diseases that affect the eye and can cause vision loss.

1 Jul 2014

18F-FGD-PET measures predict mRCC TKI response

Positron emission tomography could be used to predict the response of metastatic renal cell carcinoma to tyrosine kinase inhibitor therapy within a couple of weeks of a patient beginning treatment, research suggests.

30 Jun 2014

Therapy News and Research

New collaborative fundraising effort focuses on AYA cancer

New gene therapy for Acute Intermittent Porphyria

Australian immunologists uncover additional role for antibody-making 'B cells'

CHOP study: Children with specific gene variants may require higher doses of pain-control drugs

Researchers identify new biomarker that predicts effectiveness of glioblastoma treatment

Drug everolimus fails to improve overall survival in advanced liver cancer patients

More music therapists needed in psychiatric health care, says researcher

Aspirin, smoking influence aging processes of female genome connected to colorectal cancer

Proton beam therapy improves head and neck cancers free survival compared to IMRT

Elderly mRCC patients should not be excluded from targeted therapy option

Partial nephrectomy predicts survival among metastatic RCC patients

LINX Reflux Management System safe for patients suffering from GERD, shows new data

State highlights: Caring for Texans injured on-the-job; heroin deaths in Md.; pertussis in Calif.

CTI completes recruitment in PERSIST-1 clinical trial of pacritinib for treatment of myelofibrosis

HIV-positive people with early-stage cancer less likely to get cancer treatment

New approach may help develop more effective immunotherapy for metastatic melanoma

Researchers develop new way to identify potential therapeutic targets for drug resistant melanoma

Research could help to reduce health care charges

Researchers find unique cell type that can protect against uveitis

18F-FGD-PET measures predict mRCC TKI response

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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