Therapy News and Research

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Shark antibodies reveal evolutionary principles of immunoglobulins

Custom-tailored antibodies are regarded as promising weapons against a multitude of serious illnesses. Since they can accurately recognize specific structures on the surface of viruses, bacteria or cancer cells, they are already being deployed successfully in cancer diagnostics and therapy, as well as against numerous other diseases. The stability of the sensitive antibodies is a decisive factor in every step, from production and storage to therapeutic application.

15 May 2014

New tech could take light-based cancer treatment deep inside the body

Photodynamic therapy (PDT) is an effective treatment for easily accessible tumors such as oral and skin cancer.

15 May 2014

Cord Blood America's total revenue decreases 3% to $1.42 million in Q1 2014

Cord Blood America, Inc. today announced financial results for the quarter ended March 31, 2014.

15 May 2014

Inspire Medical Systems completes $40 million Series E financing

Inspire Medical Systems, Inc. announced today that it has completed a Series E financing of $40 million. The financing round was strategically timed to coincide with the commercial launch of the Inspire Upper Airway Stimulation (UAS) therapy in the United States.

15 May 2014

Study: Lorazepam drug not effective in treating pediatric status epilepticus

A National Institutes of Health-sponsored study published in the Journal of the American Medical Association showed that lorazepam - a widely used but not yet Food and Drug Administration approved drug for children - is no more effective than an approved benzodiazepine, diazepam, for treating pediatric status epilepticus.

15 May 2014

In-office treatment using balloon sinus dilation is as effective as FESS for chronic sinusitis

New results from a randomized trial published in the American Journal of Rhinology and Allergy demonstrate the benefits of in-office balloon dilation for sufferers of chronic sinusitis.

15 May 2014

Astellas reports efficacy, safety data of isavuconazole invasive aspergillosis SECURE study at ECCMID

Astellas reported today that the efficacy and safety data of the isavuconazole invasive aspergillosis study (SECURE) were presented at the European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) in Barcelona, Spain.

15 May 2014

Scientists find new way to predict response to platinum-based chemotherapy in women with triple-negative breast cancer

Researchers from University Hospitals (UH) Case Medical Center's Seidman Cancer Center will present findings from a study that found the presence of tumor-infiltrating lymphocytes, a type of white blood cell, ahead of treatment may help predict response to platinum-based chemotherapy in women with triple-negative breast cancer.

15 May 2014

UofL institute and physician-director receive 2 MediStar awards

An institute at the University of Louisville and the physician-director of UofL's James Graham Brown Cancer Center won two MediStar awards presented May 13 at the Hyatt Regency Louisville.

15 May 2014

Scripps Research Institute scientists show AIDS vaccine could work against changeable site on HIV

A vaccine or other therapy directed at a single site on a surface protein of HIV could in principle neutralize nearly all strains of the virus-thanks to the diversity of targets the site presents to the human immune system.

15 May 2014

Study: Wider use of medications may help reduce substance abuse, related hospital admissions

A comparatively new form of a medication for alcohol and opioid dependence that's injected once a month instead of taken orally once a day appears to be significantly more effective than some other medications - because more patients actually continue the prescribed regimen.

15 May 2014

Investigators find effective treatment for life-threatening angioedema attacks in ED

Investigators at the University of Cincinnati have found a safe and effective treatment for life-threatening angioedema attacks in the emergency department.

15 May 2014

Inotropic agents support epoprostenol initiation in severe PAH

Researchers have published a protocol for use of inotropic agents during initiation of epoprostenol therapy in patients with severe pulmonary arterial hypertension.

14 May 2014

Autoimmune epilepsy diagnostics: an interview with Dr. Joseph J. Higgins, Medical Director, Neurology, Athena Diagnostics, a business of Quest Diagnostics

Epilepsy is a group of neurological disorders often characterized by seizures and cognitive impairment due to electrical disturbances in the brain.

From Quest Diagnostics 14 May 2014

Isis Pharmaceuticals reports positive data from ISIS-GCGRRx Phase 2 study in patients with type 2 diabetes

Isis Pharmaceuticals, Inc. announced today positive data from a Phase 2 study of ISIS-GCGRRx in patients with type 2 diabetes uncontrolled on stable metformin therapy.

14 May 2014

Researchers develop new high-tech device for transferring DNA into cells

The ability to transfer a gene or DNA sequence from one animal into the genome of another plays a critical role in a wide range of medical research-including cancer, Alzheimer's disease, and diabetes.

14 May 2014

Nimotuzumab enhances chemo-radiosensitivity by promoting autophagic cell death in ESCC cells

A study which will be published in the May 2014 issue of Experimental Biology and Medicine was aimed at determining whether an EGFR-targeted therapy combined with chemo-radiotherapy can improve local tumor control effectively, compared to cytotoxic agents or irradiation alone.

14 May 2014

MedImmune to present Phase IIb asthma data on benralizumab and tralokinumab at ATS conference

AstraZeneca today announced that MedImmune, its global biologics research and development arm, will present Phase IIb data on two novel investigational molecules – benralizumab and tralokinumab – at the upcoming American Thoracic Society 2014 International Conference being held in San Diego, California, 16-21 May.

14 May 2014

Intensive insulin treatment improves survival for diabetic heart attack patients

Long-term follow-up of the DIGAMI 1 trial – a landmark study of type 2 diabetes in Sweden – shows that intensive insulin treatment prolonged life by more than 2 years in patients with diabetes after a heart attack, compared with standard treatment for diabetes, reports Dr Viveca Ritsinger from the Unit of Cardiology of the Department of Medicine, Karolinska Institute, Stockholm, Sweden and colleagues in The Lancet Diabetes & Endocrinology.

14 May 2014

Minimally invasive TAVR procedure saves more lives than open-heart surgery, shows study

For the first time, a minimally invasive transcatheter valve - tested by Baylor Research Institute in Dallas (BRI) - has been shown to save more lives than open-heart surgery, according to new research revealed at the American College of Cardiology's 2014 Scientific Sessions and published in The New England Journal of Medicine.

From Medtronic 14 May 2014

Therapy News and Research

Shark antibodies reveal evolutionary principles of immunoglobulins

New tech could take light-based cancer treatment deep inside the body

Cord Blood America's total revenue decreases 3% to $1.42 million in Q1 2014

Inspire Medical Systems completes $40 million Series E financing

Study: Lorazepam drug not effective in treating pediatric status epilepticus

In-office treatment using balloon sinus dilation is as effective as FESS for chronic sinusitis

Astellas reports efficacy, safety data of isavuconazole invasive aspergillosis SECURE study at ECCMID

Scientists find new way to predict response to platinum-based chemotherapy in women with triple-negative breast cancer

UofL institute and physician-director receive 2 MediStar awards

Scripps Research Institute scientists show AIDS vaccine could work against changeable site on HIV

Study: Wider use of medications may help reduce substance abuse, related hospital admissions

Investigators find effective treatment for life-threatening angioedema attacks in ED

Inotropic agents support epoprostenol initiation in severe PAH

Autoimmune epilepsy diagnostics: an interview with Dr. Joseph J. Higgins, Medical Director, Neurology, Athena Diagnostics, a business of Quest Diagnostics

Isis Pharmaceuticals reports positive data from ISIS-GCGRRx Phase 2 study in patients with type 2 diabetes

Researchers develop new high-tech device for transferring DNA into cells

Nimotuzumab enhances chemo-radiosensitivity by promoting autophagic cell death in ESCC cells

MedImmune to present Phase IIb asthma data on benralizumab and tralokinumab at ATS conference

Intensive insulin treatment improves survival for diabetic heart attack patients

Minimally invasive TAVR procedure saves more lives than open-heart surgery, shows study

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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