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Penn researchers find common thread linking almost all TNR expansion diseases

In a class of roughly 30 neurological disorders that includes ALS, Huntington's Disease and Fragile X Syndrome, the relevant mutant gene features sections of repeating base pair sequences known as short tandem repeats, or STRs. Healthy people have STRs of normal lengths distributed across their DNA.

19 Sep 2018

Study: CXCL14 protein is secreted by brown adipose tissue and has beneficial effects in metabolic diseases

A scientific team found that the CXCL14 protein, associated with tumor progression and organogenesis, causes beneficial effects to metabolic diseases such as obesity and diabetes.

19 Sep 2018

Scientists discover new molecules that work together to remove unwanted DNA

Scientists have discovered a new family of molecules that work together to precisely remove unwanted DNA during reproduction in single-celled, freshwater organisms called ciliates.

19 Sep 2018

Three research projects from UNIST selected as the 2018 Basic Research Projects

Three research projects proposed by UNIST researchers in the first half of this year have been selected as the 2018 Basic Research Projects in Science and Engineering.

19 Sep 2018

Researchers acquire new insights into DNA polymerases

Complex biological systems can be described as a network of chemical processes that take place in molecules. The scientists of the "ChemLife" research initiative at the University of Konstanz are working together in an equally active network with dynamic interconnections - both subject-specific and interdisciplinary.

19 Sep 2018

Tweaking nuclear pores could provide new avenue to battle against cancer

If the cell nucleus is like a bank for DNA, nuclear pores are the security doors around its perimeter. Yet more security doors aren't necessarily better: some cancer cells contain a dramatic excess of nuclear pores.

19 Sep 2018

Potential drugs to treat neurodegenerative diseases garner $3 million grant

A new four-year, $3 million grant will enable Scripps Research scientists to advance compounds that may protect neurons in diseases caused by toxic protein accumulation, including Parkinson's, ALS, Alzheimer's and Creutzfeldt-Jakob disease.

18 Sep 2018

Researchers use CRISPR screen to reveal new targets in squamous cell carcinomas

A little p63 goes a long way in embryonic development - and flaws in p63 can result in birth defects like cleft palette, fused fingers or even missing limbs.

18 Sep 2018

Microbiota in the intestines and cell stress cause colon cancer

"With our study we originally wanted to study the role of bacteria in the intestines in the development of intestinal inflammation," explains Professor Dirk Haller from the Department of Nutrition and Immunology at the Weihenstephan Science Centre of the TUM.

18 Sep 2018

Logos Biosystems releases new electrophoretic tissue clearing system with twice the features in half the space

Logos Biosystems has released the latest system for electrophoretic tissue clearing, the X-CLARITY™ Tissue Clearing System II. The new system has been upgraded with new features that make it streamlined, easier to use and more intuitive.

From Logos Biosystems 18 Sep 2018

Study aims to investigate risk factors for PPCs in surgical patients with gastric cancer

As one of the most common malignant tumors, gastric cancer occupies the second leading cause of cancer-related deaths worldwide with an increasing trend.

18 Sep 2018

Scientists find the genetic code underlying limb growth

Researchers at the Ecole Polytechnique Fédérale de Lausanne have discovered the gene code that sets the pace and order of fetal development.

18 Sep 2018

NUS researchers develop new device for quick and accurate screening of diseases

A multidisciplinary team of researchers at the National University of Singapore has developed a portable, easy-to-use device for quick and accurate screening of diseases.

18 Sep 2018

Researchers find way to map mysterious content of non-coding RNA

Researchers from the University of North Carolina have found a way of categorising long non-coding RNAs (lnc-RNAs) by their probable function.

18 Sep 2018

Zika virus vaccine shows promise for treatment of fatal glioblastoma

An international team of researchers has successfully deployed a Zika virus vaccine to target and kill human glioblastoma brain cancer stem cells, which had been transplanted into mice.

18 Sep 2018

Purifying Proteins from Mammalian Cell Culture

In many cases mammalian cells are the only option to produce recombinant proteins with correct post-translational modifications, e.g. glycosylation, which are required for proper function of the therapeutic protein.

From Sartorius 18 Sep 2018

New compound could prevent malaria parasites from maturing inside mosquito

Researchers have identified compounds that could prevent malaria parasites from being able to infect mosquitoes, halting the spread of disease.

18 Sep 2018

Researchers analyze how exposure to silver nanoparticles affects zebrafish

Silver nanoparticles are increasingly being used in consumer products, such as clothing and personal care products, in the medical and pharmaceutical industry, and in the food industry.

18 Sep 2018

People more likely to believe those with confident tone of voice than with accent

A recently published study shows that unless they speak in a confident tone of voice, you're less likely to believe someone who speaks with an accent.

18 Sep 2018

Key signaling molecule that helps stem cells make healthy bone declines as we age

With age, expression of a small molecule that can silence others goes way up while a key signaling molecule that helps stem cells make healthy bone goes down, scientists report.

18 Sep 2018