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Scientists determine trajectory and pathophysiology of post-COVID-19 syndrome

A new study utilizes multisystem imaging, along with biomarker analysis, to better understand the pathogenesis of COVID-19.

30 May 2022

Researchers gain understanding of biosynthetic mechanisms for producing cyanobacterin

Researchers in the groups of Prof. Tobias Gulder from TU Dresden and Prof. Tanja Gulder from Leipzig University have succeeded in understanding the biosynthetic mechanisms for the production of the natural product cyanobacterin, which in Nature is produced in small quantities by the cyanobacteria Scytonema hofmanni.

27 May 2022

Penn biologists show evidence of a two-sided genomic arms race involving repetitive DNA

Biological arms races are commonplace in nature. Cheetahs, for example, have evolved a sleek body form that lends itself to rapid running, enabling them to feast upon similarly speedy gazelles, the fastest of which may evade predation.

27 May 2022

A polymer-nanoparticle hydrogel to subcutaneously deliver broadly neutralizing antibodies against SARS-CoV-2

Researchers compared the polymer-nanoparticle hydrogel system and standard routes of delivery of broadly neutralizing antibodies against SARS-CoV-2 in a mouse model.

27 May 2022

Cell membrane-bound enzyme is essential for SARS-CoV-2 infectivity, study shows

The membrane-bound form of angiotensin converting enzyme 2 (ACE2) is essential for enabling infection with SARS-CoV-2, the virus that causes COVID-19, according to a study published in the journal Cell.

26 May 2022

New biomarker may enable rapid, inexpensive diagnosis of Parkinson's disease

Researchers at Kobe University and Hiroshima University have successfully developed a biomarker that will enable Parkinson's disease to be rapidly and inexpensively diagnosed from blood serum samples.

26 May 2022

Gut bacteria can reduce the effectiveness of certain blood pressure drugs

A new study from The University of Toledo College of Medicine and Life Sciences has shown gut bacteria can reduce the effectiveness of certain blood pressure drugs.

26 May 2022

Researchers report novel interactions between the SARS-CoV-2 S protein and estrogen receptor alpha

Researchers profiled the binding sites of the entire SARS-CoV-2 spike protein sequence.

26 May 2022

Study assesses the safety of breastfeeding during maternal SARS-CoV-2 infection

Researchers assessed the presence of anti-SARS-CoV-2 antibodies in human breast milk.

26 May 2022

SARS-CoV-2 variants BA.4 and BA.5 show substantial immune escape compared with BA.1 and BA.2

In a recent study posted to the bioRxiv* pre-print server, researchers characterized the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant of concern (VOC) Omicron’s new sub-lineages, BA.4, BA.5, and BA.3.

26 May 2022

After SARS-CoV-2 infection, anti-chemokine antibodies correlate with better outcomes

A recent study posted to the bioRxiv* preprint server illustrated that specific chemokine antibodies aid in recognizing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) convalescent individuals with a desirable disease course.

26 May 2022

Study illustrates risk of Omicron infection in fully vaccinated individuals

Scientists studied SARS-CoV-2 humoral responses in a healthy young person who was infected by the Omicron BA.1.15 after receiving booster vaccination.

25 May 2022

The role of pyroptosis in COVID-19

Researchers investigate the mechanisms by which SARS-CoV-2 induces NLRP3 inflammasome formation leading to pyroptosis.

25 May 2022

NYU Abu Dhabi research could pave the way for more effective cancer treatments

A team led by Professor of Biology, Senior Vice Provost of Research at NYU Abu Dhabi, and UAE national Sehamuddin Galadari, has discovered a novel structural modification in AMP-activated protein kinase (AMPK) during anticancer therapy that could pave the way for the development of more effective cancer treatments.

25 May 2022

Development of a rapid, inexpensive and highly accurate diagnostic method to fight African Swine Fever

While the attention of public health authorities has been rivetted on the current COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, many other viruses have been stealthily circling the globe, causing serious disease and death in humans and other animals.

25 May 2022

Study measures viral antigen and inflammatory biomarkers in CSF of COVID-19 patients in relation to neurologic symptoms and disease severity

Researchers investigated the impact of coronavirus disease 2019 (COVID-19) on biomarkers in the cerebrospinal fluid (CSF).

25 May 2022

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

In a recent study under review at the Scientific Reports journal and posted to the Research Square* preprint server, researchers evaluated the efficacy of messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccine BNT162b2 in cancer patients under treatment with immune checkpoint inhibitors (ICIs).

25 May 2022

Biodegradable, non-ionic polymeric nanovesicles efficiently encapsulate and deliver siRNA

Small interfering RNAs, or siRNAs, hold promise to treat tumors, through their ability to specifically knock down oncogenes that promote tumor growth, without the toxicity that accompanies chemotherapy. However, the siRNAs need a delivery vehicle to protect them from degradation and clearance on their journey through the bloodstream to the cancer tumor.

25 May 2022

Computational modeling fine tunes RBD-1C aptamer against SARS-CoV-2 S protein

Researchers used the SARS-CoV-2 sequence against aptamers to perform the in silico selection of an aptamer against the SARS-CoV-2 S protein.

24 May 2022

NIH awards first part of $30 million grant to USC team for stroke project

When administered soon after the onset of acute ischemic stroke, current approved treatments for the condition can dramatically improve patient outcomes.

24 May 2022

Enzyme News and Research

Scientists determine trajectory and pathophysiology of post-COVID-19 syndrome

Researchers gain understanding of biosynthetic mechanisms for producing cyanobacterin

Penn biologists show evidence of a two-sided genomic arms race involving repetitive DNA

A polymer-nanoparticle hydrogel to subcutaneously deliver broadly neutralizing antibodies against SARS-CoV-2

Cell membrane-bound enzyme is essential for SARS-CoV-2 infectivity, study shows

New biomarker may enable rapid, inexpensive diagnosis of Parkinson's disease

Gut bacteria can reduce the effectiveness of certain blood pressure drugs

Researchers report novel interactions between the SARS-CoV-2 S protein and estrogen receptor alpha

Study assesses the safety of breastfeeding during maternal SARS-CoV-2 infection

SARS-CoV-2 variants BA.4 and BA.5 show substantial immune escape compared with BA.1 and BA.2

After SARS-CoV-2 infection, anti-chemokine antibodies correlate with better outcomes

Study illustrates risk of Omicron infection in fully vaccinated individuals

The role of pyroptosis in COVID-19

NYU Abu Dhabi research could pave the way for more effective cancer treatments

Development of a rapid, inexpensive and highly accurate diagnostic method to fight African Swine Fever

Study measures viral antigen and inflammatory biomarkers in CSF of COVID-19 patients in relation to neurologic symptoms and disease severity

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

Biodegradable, non-ionic polymeric nanovesicles efficiently encapsulate and deliver siRNA

Computational modeling fine tunes RBD-1C aptamer against SARS-CoV-2 S protein

NIH awards first part of $30 million grant to USC team for stroke project

Understanding the DNA Damage Response in Innate Immunity eBook

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