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New discoveries on genes implicated in Fanconi anaemia

An international research consortium, which included the participation of the Mutagnesi Group from the UAB, has made outstanding progress in the study of Fanconi anaemia.

3 Jun 2007

New tests for leishmaniasis and leprosy

The Seattle-based Infectious Disease Research Institute (IDRI) and Chembio Diagnostics, Inc. have entered into two research and development agreements for the development of rapid diagnostic tests for Leishmaniasis and Leprosy, two "neglected diseases" targeted by IDRI.

1 Jun 2007

Human antibodies protect mice from H5N1 avian influenza

An international team of scientists, including researchers from the National Institute of Allergy and Infectious Diseases (NIAID), report using antibodies derived from immune cells from recent human survivors of H5N1 avian influenza to successfully treat H5N1-infected mice as well as protect them from an otherwise lethal dose of the virus.

30 May 2007

Natalizumab returns to market

Just months after receiving FDA approval, natalizumab, a medication for the treatment of multiple sclerosis (MS) and other inflammatory disorders, was voluntarily withdrawn by its manufacturers after three patients developed a brain infection known as Progressive Multifocal Leukoencephalopathy (PML).

28 May 2007

Significant breakthrough in the search for an effective malaria vaccine

One person dies of it every 30 seconds, it rivals HIV and tuberculosis as the world's most deadly infection and the vast majority of its victims are under five years old.

28 May 2007

Significant breakthrough in the search for an effective malaria vaccine

One person dies of it every 30 seconds, it rivals HIV and tuberculosis as the world's most deadly infection and the vast majority of its victims are under five years old.

24 May 2007

T helper cells and depletion in HIV

Scientists have refuted a longstanding theory of how HIV slowly depletes the body's capacity to fight infection, in new research published.

24 May 2007

Macrophages may have role blocking obesity

Macrophages - the scavenger cells of the body's immune system - are known as troublemakers for the role they play in obesity, but Stanford University School of Medicine researchers have found that the cells can also be saviors when it comes to metabolism.

22 May 2007

Potential therapeutic target for autoimmune vasculitis

A potential therapeutic target for autoimmune vasculitis has been identified by researchers of the Franz Volhard Clinic for Cardiovascular Diseases (FVK) of the Charity – University Medicine Berlin/HELIOS-Klinikum and the Max Delbruck Center for Molecular Medicine (MDC) Berlin-Buch.

16 May 2007

Atypical pathogen treatment vital in hospitalized community-acquired pneumonia patients

Hospitalized patients with community-acquired pneumonia (CAP) who received treatment regimens against atypical disease-causing pathogens reached clinical stability quicker, had fewer days of hospitalization, and had lower mortality rates as a result of their disease, according to a large new study.

16 May 2007

Natural antibodies and tissue injury

Lack of blood flow to the intestines during surgery, to the heart during a heart attack or to the brain during a stroke can cause damage to the organ involved.

15 May 2007

Inherited variations in certain genes linked to toxicity of leukemia therapy

Investigators at St. Jude Children's Research Hospital have discovered inherited variations in certain genes that make children with acute lymphoblastic leukemia (ALL) susceptible to the toxic side effects caused by chemotherapy medications.

15 May 2007

Preoperative chemotherapy reduces chemo-related infections

Giving chemotherapy to women with operable breast cancer before they have surgery 'not after' helps physicians pin down the best treatment regimen and can reduce the extent of surgery, according to a new systematic review.

11 May 2007

Coarse particulate matter in outdoor air raises bad cholesterol

Breathing air containing coarse particulate matter such as road or construction dust may cause heart problems for asthma sufferers and other vulnerable populations, according to a new study led by the University of North Carolina at Chapel Hill School of Public Health.

10 May 2007

Fluorescent nanoparticles open up new possibilities for cellular imaging

Scientists from the University of Twente, the Netherlands, have successfully exploited the optical properties of fluorescent nanoparticles to broaden the scope of single-cell microscopy.

9 May 2007

Promising new target for brain tumor therapy

A drug that targets the body's immune cells may be effective in treating malignant brain tumors, according to a new study led by researchers from Duke's Preston Robert Tisch Brain Tumor Center.

9 May 2007

How inhaled anthrax paralyzes the body's defenses

University of Florida researchers have revealed how the inhaled form of anthrax paralyzes the body's defenses and prevents immune cells from reaching the site of infection.

8 May 2007

Hepatitis C increases risk for non-Hodgkin's lymphoma

Researchers in the U.S. have found that an infection with the hepatitis C virus increases the risk of a person developing non-Hodgkin's lymphoma.

8 May 2007

Molecule that destroys bone also protects it

An immune system component that is a primary cause of bone destruction and inflammation in autoimmune diseases such as rheumatoid arthritis actually protects bone in the oral cavity from infectious pathogens that play a major role in periodontal disease in humans, research at the University at Buffalo has shown.

7 May 2007

Variants of two genes involved in the inflammatory system linked to cognitive decline after heart surgery

Duke University Medical Center researchers believe their findings could help physicians identify patients at risk of suffering mental decline after heart surgery and raises the possibility that these patients could be treated with drugs that are known to dampen the inflammatory response.

2 May 2007