Protein C News and Research

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Scientists find new signal pathway that plays vital role in learning, processing of sensory input

Scientists at Johannes Gutenberg University Mainz in Germany have discovered a new signal pathway in the brain that plays an important role in learning and the processing of sensory input. It was already known that distinct glial cells receive information from neurons.

16 Dec 2014

Ortho-Clinical Diagnostics announces availability of NEPHROCHECK Test System for AKI patients

Ortho-Clinical Diagnostics, Inc. today announced the nationwide availability to hospitals of the NEPHROCHECK Test System designed to help healthcare providers identify patients at risk of developing moderate or severe acute kidney injury (AKI) within 12 hours of patient assessment.

From Ortho-Clinical Diagnostics, Inc. 16 Dec 2014

Centenary researchers find potential way to stop spread of tumors

By blocking a widespread enzyme, Centenary researchers have shown they can slow down the movement of cells and potentially stop tumours from spreading and growing.

16 Dec 2014

TSRI scientists awarded $2.3 million grant to find ways to erase traumatic memories

Scientists from the Florida campus of The Scripps Research Institute have been awarded $2.3 million from the Department of Health and Human Services of the National Institutes of Health to better understand how memories are stored in the hopes of eventually being able to treat posttraumatic stress disorder (PTSD) by erasing traumatic memories without altering other, more benign ones.

16 Dec 2014

UC Davis researchers uncover complex relationship between p53 and Rbm38 proteins

Scientists have long known the p53 protein suppresses tumors. However, a recent animal study by UC Davis researchers has uncovered a complicated relationship between p53 and another protein, Rbm38, highlighting how the body calibrates protein levels. Too much Rbm38 reduces p53 levels, increasing the risk of cancer.

16 Dec 2014

Study provides evidence for presence of enterovirus in pancreatic islets of type 1 diabetic patients

Norwegian scientists with European partners have found evidence for the presence of Enterovirus in pancreatic islets of type 1 diabetic patients. This provides evidence consistent with the theory that a low grade Enteroviral infection in the pancreatic islets contribute to disease progression in humans.

16 Dec 2014

New MIT study implicates RNA-binding proteins in regulation of cancer

A new study from MIT implicates a family of RNA-binding proteins in the regulation of cancer, particularly in a subtype of breast cancer. These proteins, known as Musashi proteins, can force cells into a state associated with increased proliferation.

16 Dec 2014

Trastuzumab drug improves long-term survival of patients with HER-2 positive breast cancer

VCU Massey Cancer Center physician-researcher Charles E. Geyer, Jr., M.D., was the National Protocol Officer for one component of a large national study involving two National Cancer Institute-supported clinical trials that demonstrated that trastuzumab significantly improves the long-term survival of HER-2 positive breast cancer patients.

16 Dec 2014

Researchers map B cell response to non-gluten proteins of wheat in celiac disease

Researchers at Columbia University Medical Center have found that, in addition to gluten, the immune systems of patients with celiac disease react to specific types of non-gluten protein in wheat. The results were reported online in the Journal of Proteome Research.

16 Dec 2014

FL118 agent shows efficacy as personalized, targeted therapy for certain cancer tumors

A team led by Fengzhi Li, PhD, and Xinjiang Wang, PhD, of Roswell Park Cancer Institute has reported new findings regarding therapeutic targets of the novel anticancer agent FL118. Previous studies from these researchers have showed that FL118 induces cancer cell death, or apoptosis, by inhibiting expression of multiple cell-survival proteins (survivin, Mcl-1, XIAP or cIAP2).

15 Dec 2014

Higher levels of selenium linked to decreased risk of colorectal cancer

Higher levels of selenium are associated with a decreased risk of colorectal cancer, according to new research published in the International Journal of Cancer (December).

15 Dec 2014

Children who skip meals more likely to have excess body fat, increased cardiometabolic risk

Children who skip main meals are more likely to have excess body fat and an increased cardiometabolic risk already at the age of 6 to 8 years, according to a Finnish study. A higher consumption of sugary drinks, red meat and low-fat margarine and a lower consumption of vegetable oil are also related to a higher cardiometabolic risk.

15 Dec 2014

UT Southwestern researchers identify possible therapy to treat neurofibromatosis type 1

UT Southwestern Medical Center researchers have identified a possible therapy to treat neurofibromatosis type 1 or NF1, a childhood neurological disease characterized by learning deficits and autism that is caused by inherited mutations in the gene encoding a protein called neurofibromin.

15 Dec 2014

ADIPOQ gene variations linked to colorectal cancer risk, new study reveals

Adiponectin, a collagen-like protein secreted by fat cells, derives from the ADIPOQ gene. Variations in this gene may increase risk for type 2 diabetes, cardiovascular disease, and various cancers. A new study that links specific variations in the ADIPOQ gene to either higher or lower colorectal cancer risk is published in Genetic Testing and Molecular Biomarkers, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

15 Dec 2014

Maf1 protein that makes other proteins also controls fat levels in the body

Like a smart sensor that adjusts the lighting in each room and a home's overall temperature, a protein that governs the making of other proteins in the cell also appears capable of controlling fat levels in the body.

14 Dec 2014

New study compares usefulness of two biomarkers released into the blood after TBI

In cases of traumatic brain injury (TBI), predicting the likelihood of a cranial lesion and determining the need for head computed tomography (CT) can be aided by measuring markers of bone injury in the blood.

14 Dec 2014

Researchers uncover mechanism that helps white fat cells to become browner

White adipose tissue stores excess calories as fat that can be released for use in other organs during fasting. Mammals also have small amounts of brown adipose tissue, which primarily acts as an effective fat burner for the production of heat. Now researchers from the University of Southern Denmark have uncovered the mechanism by which white fat cells from humans gets reprogrammed to become browner.

14 Dec 2014

UR researchers on track to solve mystery of weight gain

University of Rochester researchers believe they're on track to solve the mystery of weight gain - and it has nothing to do with indulging in holiday eggnog.

12 Dec 2014

Danish researchers working on new type of vaccine that targets disease causing bacterium

When we acquire diarrhea on a vacation, it is often caused by a bacterial infection. Now a Danish research team is working on a new type of vaccine design targeting the disease causing bacterium - if it works it may very well revolutionize not only the prevention of this disease, but also offer protection against other pathogens with a heavy disease burden such as Mycobacterium tuberculosis and antibiotic-resistant Staphylococcus aureus (MRSA).

12 Dec 2014

Three studies reveal effects of blocking androgen receptors in breast cancer

Three studies presented by University of Colorado Cancer Center researchers at the San Antonio Breast Cancer Symposium 2014 demonstrate the effects of blocking androgen receptors in breast cancer.

12 Dec 2014

Protein C News and Research

Scientists find new signal pathway that plays vital role in learning, processing of sensory input

Ortho-Clinical Diagnostics announces availability of NEPHROCHECK Test System for AKI patients

Centenary researchers find potential way to stop spread of tumors

TSRI scientists awarded $2.3 million grant to find ways to erase traumatic memories

UC Davis researchers uncover complex relationship between p53 and Rbm38 proteins

Study provides evidence for presence of enterovirus in pancreatic islets of type 1 diabetic patients

New MIT study implicates RNA-binding proteins in regulation of cancer

Trastuzumab drug improves long-term survival of patients with HER-2 positive breast cancer

Researchers map B cell response to non-gluten proteins of wheat in celiac disease

FL118 agent shows efficacy as personalized, targeted therapy for certain cancer tumors

Higher levels of selenium linked to decreased risk of colorectal cancer

Children who skip meals more likely to have excess body fat, increased cardiometabolic risk

UT Southwestern researchers identify possible therapy to treat neurofibromatosis type 1

ADIPOQ gene variations linked to colorectal cancer risk, new study reveals

Maf1 protein that makes other proteins also controls fat levels in the body

New study compares usefulness of two biomarkers released into the blood after TBI

Researchers uncover mechanism that helps white fat cells to become browner

UR researchers on track to solve mystery of weight gain

Danish researchers working on new type of vaccine that targets disease causing bacterium

Three studies reveal effects of blocking androgen receptors in breast cancer

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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