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Researchers develop tissue engineered bone grafts for healing large bone defects

Bone is one of the most frequently transplanted tissues. And the demand is rising. Transplants treat large defects like those caused by trauma, complicated fractures, tumour resection or osteoporosis.

20 Jun 2014

New model for HIV-1 infection offers promising option for clinical research

HIV-1, the virus responsible for most cases of AIDS, is a very selective virus. It does not readily infect species other than its usual hosts — humans and chimpanzees.

20 Jun 2014

Osteoarthritis may be treated with stem cell mobilization therapy

Researchers in Taiwan have found that peripheral blood stem cells can be "mobilized" by injection of a special preparation of granulocyte colony-stimulating factor (G-CSF) into rats that modeled osteoarthritis (OA).

20 Jun 2014

Yap1 oncogene drives recurrence and progression of pancreatic cancer

Pancreatic cancer tumors addicted to mutant Kras signaling for their growth and progression have a ready-made substitute to tap if they're ever forced to go cold-turkey on the mutant oncogene, scientists at The University of Texas MD Anderson Cancer Center report in the journal Cell.

20 Jun 2014

New research reveals gene's role in type 1 diabetes

New research describes details of how a diabetes-related gene functions on a biological pathway that affects the release of insulin. The study authors say that finding drugs that act on that pathway may eventually lead to a new treatment for type 1 diabetes.

20 Jun 2014

Researchers shed new light on how gliomas cells migrate in brain and cause devastating tumors

Researchers at the University of Alabama at Birmingham have shed new light on how cells called gliomas migrate in the brain and cause devastating tumors.

20 Jun 2014

Neurosurgeons implant new type of electrical stimulator to control seizures

On June 18, neurosurgeons at the University of Alabama at Birmingham implanted a new type of electrical stimulator to control seizures in patients with difficult-to-control epilepsy.

20 Jun 2014

Arthritis drug promotes hair growth in hairless man

A man with almost no hair on his body has grown a full head of it after a novel treatment by doctors at Yale University.

20 Jun 2014

Men with prostate cancer achieve stronger muscles and remain active through playing football

Men with prostate cancer aged 43‒74 achieve bigger and stronger muscles, improve functional capacity, gain positive social experiences and the desire to remain active through playing football for 12 weeks.

20 Jun 2014

Clinical trial shows that selumetinib drug can delay progression of metastatic uveal melanoma

For the first time, a therapy has been found that can delay progression of metastatic uveal melanoma, a rare and deadly form of melanoma of the eye.

20 Jun 2014

New driver of atherosclerosis may prove to be promising therapeutic target

A new driver of atherosclerosis has been identified by researchers at UT Southwestern Medical Center. This molecule, known as 27HC (27-hydroxycholesterol), has been found to exacerbate the development of the condition, and may prove to be a promising therapeutic target.

20 Jun 2014

Playing football could help lower blood pressure in women aged 35-50

The World Cup in Brazil may be attracting a global armchair audience of millions, but new research has shown that playing football could help lower blood pressure in women aged 35-50.

20 Jun 2014

CBT reduces urge to obey command hallucinations

The COMMAND trial shows that cognitive behaviour therapy can bring about a “clinically meaningful” reduction in the rate at which patients comply with command hallucinations.

19 Jun 2014

March of Dimes Canada, U of T sign deal to advance research in brain injuries, stroke

Today, March of Dimes Canada and the University of Toronto (U of T) signed a $1.5 million agreement to advance research in recovery from brain injuries and stroke, making the donation to the University the largest made by the national charitable organization in its over 60 year history.

19 Jun 2014

Review on effects of treating cholera with antimicrobial drugs

Researchers from the Cochrane Infectious Diseases Group, co-ordinated through the editorial base in LSTM, conducted an independent review of the effects of treating cholera with antimicrobial drugs, published in The Cochrane Library today.

19 Jun 2014

Researchers find shared genetic link in autoimmune response among PV patients

Autoimmune disease occurs when the body's own natural defense system rebels against itself. One example is pemphigus vulgaris (PV), a blistering skin disease in which autoantibodies attack desmoglein 3 (Dsg3), the protein that binds together skin cells.

19 Jun 2014

New article explores ethical issues and global health impact of counterterrorism

The surge in murders of polio vaccination workers in Pakistan has made headlines this year, but little attention has been devoted to the ethical issues surrounding the global health impact of current counterterrorism policy and practice. An essay in the Hastings Center Report reviews the range of harms to population health traceable to counterterrorism operations.

19 Jun 2014

Apitope starts preclinical development of ATX-GD-459 for Graves' disease treatment

Apitope, the drug discovery and development company focused on disease-modifying treatments for patients with autoimmune and allergic diseases, announced today that it has started preclinical development of its novel peptide therapy ATX-GD-459 for the treatment of Graves' disease.

19 Jun 2014

UT Arlington researchers use portable device to map brain activity responses during cognitive activities

UT Arlington researchers have successfully used a portable brain-mapping device to show limited prefrontal cortex activity among student veterans with Post Traumatic Stress Disorder when they were asked to recall information from simple memorization tasks.

19 Jun 2014

UC Irvine Health to use $3.4 million NIH grant to examine "Transition of Care in CKD"

UC Irvine Health will use a $3.4 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health to examine the "Transition of Care in Chronic Kidney Disease (CKD)."

19 Jun 2014

Therapy News and Research

Researchers develop tissue engineered bone grafts for healing large bone defects

New model for HIV-1 infection offers promising option for clinical research

Osteoarthritis may be treated with stem cell mobilization therapy

Yap1 oncogene drives recurrence and progression of pancreatic cancer

New research reveals gene's role in type 1 diabetes

Researchers shed new light on how gliomas cells migrate in brain and cause devastating tumors

Neurosurgeons implant new type of electrical stimulator to control seizures

Arthritis drug promotes hair growth in hairless man

Men with prostate cancer achieve stronger muscles and remain active through playing football

Clinical trial shows that selumetinib drug can delay progression of metastatic uveal melanoma

New driver of atherosclerosis may prove to be promising therapeutic target

Playing football could help lower blood pressure in women aged 35-50

CBT reduces urge to obey command hallucinations

March of Dimes Canada, U of T sign deal to advance research in brain injuries, stroke

Review on effects of treating cholera with antimicrobial drugs

Researchers find shared genetic link in autoimmune response among PV patients

New article explores ethical issues and global health impact of counterterrorism

Apitope starts preclinical development of ATX-GD-459 for Graves' disease treatment

UT Arlington researchers use portable device to map brain activity responses during cognitive activities

UC Irvine Health to use $3.4 million NIH grant to examine "Transition of Care in CKD"

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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