Therapy News and Research

RSS

Weight loss most important factor for improving cardiovascular health in obese OSA patients

Obesity and obstructive sleep apnea (OSA) tend to co-exist and are associated with a variety of cardiovascular risk factors, including inflammation, insulin resistance, abnormal cholesterol, and high blood pressure. While effective therapies are available for OSA, researchers are still unclear about what interventions are most effective in reducing the burden of risk factors for cardiovascular disease associated with OSA in obese patients.

13 Jun 2014

Dancing eases hip or knee pain and helps older adults move better

Dancing eases hip or knee pain and helps older adults move better, according to a small Saint Louis University study.

13 Jun 2014

New class of tumor-targeting agents can seek out dozens of solid tumors

Scientists at the University of Wisconsin Carbone Cancer Center (UWCCC) report that a new class of tumor-targeting agents can seek out and find dozens of solid tumors, even illuminating brain cancer stem cells that resist current treatments.

13 Jun 2014

Cranial ultrasound has greater sensitivity than temporal artery biopsy in diagnosis of GCA

A new study presented for the first time today at the European League Against Rheumatism Annual Congress (EULAR 2014), shows that cranial ultrasound has a greater sensitivity than temporal artery biopsy,* and a comparable specificity in the diagnosis of Giant Cell Arteritis (GCA).

13 Jun 2014

Sutter Health invests $11.5M to install patient safety equipment across Northern California

Today, not-for-profit Sutter Health announces an $11.5 million commitment to install overhead patient lifts at 19 intensive care units and acute rehabilitation centers across its Northern California network.

12 Jun 2014

BRI researchers use tetramer technology to find T cells that drive rheumatoid arthritis

Researchers at Benaroya Research Institute at Virginia Mason used cutting-edge tetramer technology developed at BRI to find the T cells that drive rheumatoid arthritis (RA). "By using tetramer technology, we were able to examine whether T cells in people with rheumatoid arthritis were increased in number or were unique in other ways," says BRI Associate Director Jane Buckner, MD, who led the study with BRI Tetramer Core Laboratory Manager Eddie James, PhD.

12 Jun 2014

One-third of PsA patients not receiving adalimumab doses to achieve optimal clinical benefit

Data presented today at the European League Against Rheumatism Annual Congress showed that a significant number of patients with psoriatic arthritis (PsA) were not receiving doses of the tumour necrosis factor-alpha (TNFα) inhibitor adalimumab necessary to achieve optimal clinical benefit.

12 Jun 2014

New path may lead to powerful adjunctive novel therapy for PTSD treatment

There are currently only two FDA-approved medications for the treatment of posttraumatic stress disorder (PTSD) in the United States. Both of these medications are serotonin uptake inhibitors. Despite the availability of these medications, many people diagnosed with PTSD remain symptomatic, highlighting the need for new medications for PTSD treatment.

12 Jun 2014

DNA methylation identified as potential anti-TNF response biomarker for RA

DNA methylation has been identified as a potential biomarker of response to etanercept and adalimumab in patients with rheumatoid arthritis (RA) according to preliminary results from one of the largest methylome-wide investigations of treatment response to anti-TNF therapies.

12 Jun 2014

Cancer drug offers protection against thrombosis

Case Western Reserve University researchers have discovered that an existing drug used to help cancer patients has the potential to protect thousands of others from the often-deadly impact of vascular clots.

12 Jun 2014

Janssen, Viiv Healthcare to develop single tablet regimen for maintenance treatment of HIV

Janssen R&D Ireland Ltd announced today that they have entered into a collaboration with ViiV Healthcare to develop and commercialize a new single tablet regimen containing Janssen's Non-Nucleoside Reverse Transcriptase Inhibitor rilpivirine (marketed as EDURANT®) and ViiV's Integrase Inhibitor dolutegravir(marketed as TIVICAY®) as the sole active ingredients for the maintenance treatment of people living with Human Immunodeficiency Virus (HIV).

12 Jun 2014

Ferrer recruits first patient in second phase III trial of Ozenoxacin for treatment of impetigo

Ferrer, a privately-held Spanish pharmaceutical company, today announces that the first patient has been recruited into a second phase III trial of Ozenoxacin, formulated as a topical treatment for infectious dermatological conditions in adult and paediatric patients with impetigo. The study is scheduled to complete in Q1, 2015.

12 Jun 2014

TxCell receives Certificate of GMP compliance for cell therapy manufacturing facility in France

TxCell SA, a biotechnology company developing innovative, personalized cell-based immunotherapies using antigen specific regulatory T-cells (Ag-Tregs) for severe chronic inflammatory and autoimmune diseases, announces today that it has been granted Certificate of Good Manufacturing Practice (GMP) compliance for its cell therapy manufacturing facility in Besançon, France.

12 Jun 2014

Researchers study structural aspects of DNA-particle/lipid interface directly using x-ray scattering

Scientists seeking ways to engineer the assembly of tiny particles measuring just billionths of a meter have achieved a new first-the formation of a single layer of nanoparticles on a liquid surface where the properties of the layer can be easily switched.

11 Jun 2014

Molecular mechanisms regulating tumour initiation in skin SCC uncovered

Advanced online publication in Nature: Researchers at the Université libre de Bruxelles, ULB uncover the molecular mechanisms regulating tumour initiation and cancer stem cells functions in skin squamous cell carcinoma.

11 Jun 2014

Auxilium and Prasco introduce authorized generic version of Testim

Auxilium Pharmaceuticals, Inc., a fully integrated specialty biopharmaceutical company, today announced that it has partnered with Prasco, LLC ("Prasco") to introduce an Authorized Generic version of Testim® (testosterone gel).

11 Jun 2014

New research collaboration aims to develop better therapies for autoimmune diseases

Seattle Children's Research Institute and biotechnology company Kineta, Inc. today launched the Alliance for Children's Therapeutics (ACT), a first-of-its-kind pediatric research and funding collaboration designed to speed development of new medications for children and teens with lupus nephritis and other autoimmune diseases like multiple sclerosis, Type 1 diabetes and rheumatoid arthritis.

11 Jun 2014

Therapy News and Research

Weight loss most important factor for improving cardiovascular health in obese OSA patients

Dancing eases hip or knee pain and helps older adults move better

New class of tumor-targeting agents can seek out dozens of solid tumors

Cranial ultrasound has greater sensitivity than temporal artery biopsy in diagnosis of GCA

Sutter Health invests $11.5M to install patient safety equipment across Northern California

BRI researchers use tetramer technology to find T cells that drive rheumatoid arthritis

One-third of PsA patients not receiving adalimumab doses to achieve optimal clinical benefit

New path may lead to powerful adjunctive novel therapy for PTSD treatment

DNA methylation identified as potential anti-TNF response biomarker for RA

Cancer drug offers protection against thrombosis

Janssen, Viiv Healthcare to develop single tablet regimen for maintenance treatment of HIV

Ferrer recruits first patient in second phase III trial of Ozenoxacin for treatment of impetigo

TxCell receives Certificate of GMP compliance for cell therapy manufacturing facility in France

Researchers study structural aspects of DNA-particle/lipid interface directly using x-ray scattering

Molecular mechanisms regulating tumour initiation in skin SCC uncovered

Auxilium and Prasco introduce authorized generic version of Testim

New research collaboration aims to develop better therapies for autoimmune diseases

‘Real-world’ ambrisentan data unveiled

Hunterdon Regional Cancer Center offers immuno-therapy clinical trial for lung cancer

Text messages to smokers' mobile phones help quit smoking

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

Latest News