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Modified Nurr1 protein may pave way for new Parkinson's therapy

Researchers have modified the protein Nurr1 so that it can enter cells from the outside. Nurr1 deficiency may be one of the causes of Parkinson's disease.

31 Aug 2018

Researchers predict how splicing errors impact disease risk

No one knows how many times in a day, or even an hour, the trillions of cells in our body need to make proteins.

31 Aug 2018

Jaw joint bone appears to evolve based on animal's size rather than its diet

Chewing: We don't think about it, we just do it. But biologists don't know a lot about how chewing behavior leaves telltale signs on the underlying bones.

31 Aug 2018

Neurons play active role in triggering a defense mechanism that leads to their own damage

Rasmussen's encephalitis is a rare autoimmune disease that primarily affects children and can lead to seizures.

31 Aug 2018

Researchers discover materials which form new presynapses for release of transmitters

Synapses are the interfaces for information exchange between neurons. Teams of scientists working with Professor Dr. Volker Haucke, Director at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie and Professor at the Freie Universitaet Berlin, and Professor Dr. Stephan Sigrist at the Freie Universität Berlin discovered the materials, which form new presynapses for the release of transmitters. The findings may help to design better nerve-regenerating therapies in the future.

31 Aug 2018

Research may hold key to unlocking cause and finding treatment for age-related hearing loss

Age-related hearing loss is among the top three chronic conditions affecting adults 65 years or older, according to the National Center for Health Statistics.

31 Aug 2018

Leukogene receives STTR grant to optimize compound for treatment-resistant multiple myeloma

A $2 million phase 2 Small Business Technology Transfer grant to optimize a promising new compound that has shown efficacy in preclinical studies against treatment-resistant multiple myeloma has been awarded to a Medical University of South Carolina startup company, Leukogene Therapeutics, Inc., in collaboration with MUSC researcher and company founder, Nathan G. Dolloff, Ph.D. Dolloff is an assistant professor in the Department of Cell and Molecular Pharmacology & Experimental Therapeutics at MUSC and a member of MUSC Hollings Cancer Center.

31 Aug 2018

Specific protein promotes processes associated with cancer aggressiveness, reports study

Japanese researchers have revealed for the first time that a specific protein plays a critical role in the development and metastasis of highly aggressive prostate and breast cancer cells.

31 Aug 2018

Gut bacteria helps develop more beige fat with restricted calorie intake

Mice with a lower calorie intake live longer and are both healthier and leaner. A team of researchers funded by the SNSF may have found the reason for this positive effect: much of it is down to gut microbial communities and how they affect the immune system.

31 Aug 2018

Muscle dystrophy treatment in dogs with Crispr gene editing

Researchers in the United States have shown that genetically caused muscular dystrophy in dogs could be corrected using genetic editing tools. Muscular dystrophy is one of the most common fatal genetic conditions seen in children and is also seen in dogs

31 Aug 2018

Research team to investigate how blood flow influences formation of plaque

Atherosclerosis - the narrowing of arteries due to plaque buildup - is the underlying reason for the majority of strokes and heart attacks. When atherosclerosis occurs in the arteries that carry blood to the heart muscle, it is called coronary artery disease, the No. 1 killer of Americans.

30 Aug 2018

Researchers discover potential new approach to block growth of HER2 positive breast cancer

Researchers at Mayo Clinic have identified an important new pathway by which HER2 positive breast cancers grow and have discovered that a dietary supplement called cyclocreatine may block the growth of HER2 positive breast cancer.

30 Aug 2018

TGHRI scientists detail role of insulin as a boost to the immune system

The role of insulin as a boost to the immune system to improve its ability to fight infection has been detailed for the first time by Toronto General Hospital Research Institute scientists.

30 Aug 2018

Fluorescent protein sensor detects changes in cellular oxygen levels with very high sensitivity

Based on a protein from E. coli, scientists at Tokyo Institute of Technology have developed a fluorescent protein sensor able to provide real-time information on dynamic changes in oxygen levels with very high sensitivity.

30 Aug 2018

Researchers provide new virulence clues through genomic study of anthrax strains

By analyzing genomic sequences from more than 400 strains of the bacterium that causes anthrax, researchers have provided the first evidence that the severity - technically known as virulence - of specific strains may be related to the number of copies of certain plasmids they carry.

30 Aug 2018

B Cell News and Research

Modified Nurr1 protein may pave way for new Parkinson's therapy

Researchers predict how splicing errors impact disease risk

Jaw joint bone appears to evolve based on animal's size rather than its diet

Neurons play active role in triggering a defense mechanism that leads to their own damage

Researchers discover materials which form new presynapses for release of transmitters

Research may hold key to unlocking cause and finding treatment for age-related hearing loss

Leukogene receives STTR grant to optimize compound for treatment-resistant multiple myeloma

Specific protein promotes processes associated with cancer aggressiveness, reports study

Gut bacteria helps develop more beige fat with restricted calorie intake

Muscle dystrophy treatment in dogs with Crispr gene editing

Research team to investigate how blood flow influences formation of plaque

Researchers discover potential new approach to block growth of HER2 positive breast cancer

TGHRI scientists detail role of insulin as a boost to the immune system

Fluorescent protein sensor detects changes in cellular oxygen levels with very high sensitivity

Researchers provide new virulence clues through genomic study of anthrax strains

Study shows B cells could play reciprocal roles in pathogenesis of systemic sclerosis

Study: Matcha green tea kills breast cancer stem cells

Modified T lymphocytes prevent nerve cell damage in encephalitis

HKBU chemists discover metal-based inhibitor to treat triple-negative breast cancer

New model could predict personalized waiting time for progression in colorectal cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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