B Cell News and Research

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Scientists explore DNA replication errors that can lead to cancer

Scientists at Hollings Cancer Center at the Medical University of South Carolina have found that some cells can divide without a molecule that was previously thought necessary.

30 Aug 2018

Researchers discover brain cells that express sense of time within experiences, memories

Researchers at the Kavli Institute for Systems Neuroscience in Trondheim, Norway have discovered a network of brain cells that express our sense of timewithin experiences and memories.

30 Aug 2018

Novel approach reveals metabolic vulnerabilities in kidney cancer

In order to halt the growth of cancer cells, you have to know what feeds them. Researchers at the nationally recognized Kidney Cancer Program at UT Southwestern's Harold C. Simmons Comprehensive Cancer Center have developed a novel approach using glucose that may open up new opportunities for therapeutic intervention.

30 Aug 2018

Study adds more evidence to underlying autoimmune mechanisms in type 1 diabetes

Immune reactions are usually a good thing - the body's way of eliminating harmful bacteria and other pathogens. But people also rely on molecular "brakes," or checkpoints, to keep immune systems from attacking their own cells and organs and causing so-called autoimmune disease.

29 Aug 2018

Soluble versions of immune cell protein could help treat Alzheimer's disease, study reveals

Researchers at the University of Florida have discovered that a modified version of an important immune cell protein could be used to treat Alzheimer's disease.

29 Aug 2018

Using novel gene therapy to cure infants born with severe combined immunodeficiency

Out of every 60,000 births, a baby arrives to face the world without a fully functioning immune system leaving them unequipped to fight even the most common infections.

29 Aug 2018

Scientists discover potential treatment for Alzheimer’s disease

Scientists discovered a modified version of an immune cell receptor called a toll-like receptor that could be used as a treatment for Alzheimer’s disease.

29 Aug 2018

Researchers uncover why some cancers grow faster than others

University of Toronto researchers have uncovered why some cancers grow faster than others. The team led by Liliana Attisano, Professor in U of T's Donnelly Centre for Cellular and Biomolecular Research, has identified a protein called NUAK2, which is produced by cancer cells to boost their proliferation and whose presence in tumors is associated with poor disease prognosis.

29 Aug 2018

Researchers discover reason why many bladder cancer patients do not respond to immunotherapy

Mount Sinai researchers have discovered that a particular type of cell present in bladder cancer may be the reason why so many patients do not respond to the groundbreaking class of drugs known as PD-1 and PD-L1 immune checkpoint inhibitors, which enable the immune system to attack tumors.

29 Aug 2018

Cherwell confirms support for conference addressing key challenges in aseptic manufacturing of ATMPs

Cherwell Laboratories, supplier of environmental monitoring and process validation products, has confirmed its continued support for the Pharmaceutical & Healthcare Sciences Society - UCL Q3P Annual Conference 2018.

29 Aug 2018

Protein aggregates may play protection role against toxic stresses

Protein aggregates have a bad reputation in conditions such as Alzheimer’s disease and Parkinson’s disease, but in bacteria, inheritance of aggregates by daughter cells may help protect against the same toxic stresses that triggered them in parental cells, according to a new study publishing 28 August in the open access journal PLOS Biology, by Sander Govers, Abram Aertsen, and colleagues at KU Leuven, Belgium.

29 Aug 2018

Study suggests new strategies for using cell metabolism to treat cancer

Researchers at the University of Cincinnati College of Medicine have discovered that cell metabolism plays an important role in the ability of cells to start a survival program called autophagy, an unwanted side effect of some anti-cancer drugs that helps some tumor cells dodge treatment and eventually regrow into new tumors.

29 Aug 2018

New approach to assess kidney tumors could prevent patients from undergoing unnecessary surgery

A research team from Roswell Park Comprehensive Cancer Center has discovered a way to use computed tomography imaging to assess kidney tumors that test positive for the biomarker CD117 and accurately determine before surgery, whether the tumor is benign or malignant.

29 Aug 2018

Researchers find how NF2 gene mutations lead to out-of-control cellular proliferation

A team of Massachusetts General Hospital Cancer Center researchers has determined one way that mutations in a gene involved in a rare, hereditary cancer syndrome lead to out-of-control cellular proliferation.

29 Aug 2018

Researchers identify neutrophil progenitor in the bone marrow of mice and humans

Neutrophils - short-lived, highly mobile and versatile - outnumber all other immune cells circulating through the blood stream.

29 Aug 2018

New technique for mapping flow of biomolecules in tumor microenvironment

Cancer researchers struggle to identify tumor cells that are interspersed within nonmalignant tissues because tumor cells exploit the tissue environment and monopolize available resources to continue growing.

29 Aug 2018

Scientists reveal how immune system strives to protect the lungs of infants with flu

The immune system appears to put a premium on maintaining lung function in infants infected with the influenza virus by mounting a rapid response to repair damaged cells, according to research led by St. Jude Children’s Research Hospital. The findings appear today in the scientific journal Immunity.

29 Aug 2018

Researchers enlist genes that control production of cellular energy stored in ATP molecules

Everything the body does--your brain thinking, your heart beating, your cells growing--requires energy. Consequently, it comes as no surprise that disruptions in energy production can contribute to a wide range of diseases.

29 Aug 2018

Study could open new therapeutic avenues to attack herpesviruses

Human cytomegalovirus is a leading cause of birth defects and transplant failures. As it's evolved over time, this virus from the herpes family has found a way to bypass the body's defense mechanisms that usually guards against viral infections. Until now, scientists couldn't understand how it manages to do so.

28 Aug 2018

A non-canonical approach may improve radiation treatment for cancer

Although the success or failure of radiation therapy for cancer has long been associated with the intrinsic radio-resistance or radio-sensitivity of tumor cells, a new approach is demonstrating that radiation can take credit for an additional benefit - causing highly effective secondary immune responses that can enhance anti-tumor immunity.

28 Aug 2018

B Cell News and Research

Scientists explore DNA replication errors that can lead to cancer

Researchers discover brain cells that express sense of time within experiences, memories

Novel approach reveals metabolic vulnerabilities in kidney cancer

Study adds more evidence to underlying autoimmune mechanisms in type 1 diabetes

Soluble versions of immune cell protein could help treat Alzheimer's disease, study reveals

Using novel gene therapy to cure infants born with severe combined immunodeficiency

Scientists discover potential treatment for Alzheimer’s disease

Researchers uncover why some cancers grow faster than others

Researchers discover reason why many bladder cancer patients do not respond to immunotherapy

Cherwell confirms support for conference addressing key challenges in aseptic manufacturing of ATMPs

Protein aggregates may play protection role against toxic stresses

Study suggests new strategies for using cell metabolism to treat cancer

New approach to assess kidney tumors could prevent patients from undergoing unnecessary surgery

Researchers find how NF2 gene mutations lead to out-of-control cellular proliferation

Researchers identify neutrophil progenitor in the bone marrow of mice and humans

New technique for mapping flow of biomolecules in tumor microenvironment

Scientists reveal how immune system strives to protect the lungs of infants with flu

Researchers enlist genes that control production of cellular energy stored in ATP molecules

Study could open new therapeutic avenues to attack herpesviruses

A non-canonical approach may improve radiation treatment for cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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