Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Simple blood test may be a great advance for people with and at risk for Alzheimer's

A simple blood test for Alzheimer's would be a great advance for individuals with - and at risk for - the disease, families, doctors and researchers.

28 Jul 2020

New multi-analyte blood test may open up new potentials in personalized medicine

Similar to blood sugar, various biomarkers could in future be identified using just a few drops of blood. Researchers at Ruhr-Universität Bochum are developing a multi-analyte test strip for this purpose that will open up new potentials in personalised medicine by facilitating the continuous measurement of various parameters.

28 Jul 2020

Study identifies phosphorylation-based biomarkers to guide cancer therapy

Precision medicine in cancer treatment uses genetic changes in the cancer cells to select the best therapies for individual patients.

28 Jul 2020

OU physician receives $1.6 million NIH grant for knee osteoarthritis research

By the time they turn 65, at least half of people suffer from osteoarthritis, a condition that impairs quality of life and cannot be slowed by medication.

28 Jul 2020

UArizona aims to develop a device for quick and accurate detection of pathogens, biological threats

To better protect individuals serving on the front lines of battlefields or dealing with an event like the current COVID-19 health crisis or potential future pandemics, scientists at the University of Arizona College of Medicine - Phoenix are leading an effort to develop a device for easy, quick and accurate detection of pathogens and biological threats.

28 Jul 2020

Indiana University School of Medicine leads the first study of Diabetic Foot Consortium

Indiana University School of Medicine is leading the first study of the national Diabetic Foot Consortium sponsored by the National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

25 Jul 2020

First-ever multicenter network to study diabetic foot ulcers

Funded by the National Institutes of Health, six U.S. research institutions are launching the first-ever multicenter network to study diabetic foot ulcers, a common and burdensome complication of diabetes and the leading cause of lower limb amputations in the United States.

25 Jul 2020

Non-invasive urine test being offered free to the NHS to help clear bladder cancer diagnoses backlog

A HIGHLY accurate urine test which can rule out bladder cancer with a negative-predictive value of 99% using a hospital laboratory’s standard ELISA testing equipment is today being offered free to the NHS to help urologists clear the backlog of people waiting for a diagnosis and monitoring as a result of COVID-19 hospital closures.

25 Jul 2020

SphingoTec launches point-of-care test for bio-ADM, a biomarker for life threatening endothelial dysfunction

Diagnostics company SphingoTec GmbH today announced the launch of its IB10 sphingotest® bio-ADM®, a CE-IVD-marked point-of-care test to quantitatively determine blood levels of Bioactive Adrenomedullin. Blood levels of bio-ADM® reflect in real-time the functional status of the endothelium, the inner cell sheet of blood vessels.

24 Jul 2020

Epigenomic modifications play key role in the development of lung tumors

As cancer cells evolve, many of their genes become overactive while others are turned down. These genetic changes can help tumors grow out of control and become more aggressive, adapt to changing conditions, and eventually lead the tumor to metastasize and spread elsewhere in the body.

23 Jul 2020

Ultivue and OracleBio partner to help advance personalized tumor characterization and clinical oncology research using multiplex immunofluorescence

Ultivue and OracleBio partner to help further insights and advance personalized tumor characterization in translational and clinical oncology research.

From Ultivue 23 Jul 2020

C-Path gets positive response from FDA for drug-induced skeletal muscle injury safety biomarkers

Critical Path Institute announced today that the Biomarker Qualification Program at the Center for Drug Evaluation and Research in the U.S. Food and Drug Administration issued a positive response to the Letter of Intent developed by C-Path's Predictive Safety Testing Consortium and Duchenne Regulatory Science Consortium, for a panel of four safety biomarkers of acute drug-induced skeletal muscle injury.

23 Jul 2020

SphingoTec introduces a CE-IVD-marked point-of-care test to determine blood levels of bio-ADM

Diagnostics company SphingoTec GmbH today announced the launch of its IB10 sphingotest bio-ADM, a CE-IVD-marked point-of-care test to quantitatively determine blood levels of Bioactive Adrenomedullin (bio-ADM).

22 Jul 2020

Novel biomarkers for diagnosis of ureteropelvic junction obstruction in infants

One in every 500 babies is born with a condition called ureteropelvic junction obstruction (UPJO), an obstruction of the ureter that prevents urine from flowing from one or both of the kidneys into the bladder.

22 Jul 2020

Scientific evidence shows GLDH is a safe biomarker for drug-induced liver injury

Critical Path Institute (C-Path) announced today that the Biomarker Qualification Program (BQP) at the Center for Drug Evaluation and Research (CDER) from the U.S. Food and Drug Administration (FDA) issued a positive response to the Qualification Plan (QP) for glutamate dehydrogenase (GLDH) as a safety biomarker for drug-induced liver injury (DILI), developed by C-Path's Predictive Safety Testing Consortium (PSTC) and Duchenne Regulatory Science Consortium (D-RSC).

22 Jul 2020

Glycome shift in epidermal stem cells could serve as potential biomarker of aging

Age shows nowhere better than on the skin. The ravages of time on skin and the epidermal stem cells that differentiate to replenish its outer layer have been hypothesized, but there has been no method to evaluate their aging at the molecular level.

21 Jul 2020

Newly identified gene biomarker can distinguish atopic dermatitis and psoriasis with excellent accuracy

Mount Sinai researchers have pinpointed a single gene biomarker, nitride oxide synthase 2 (NOS2) that can distinguish atopic dermatitis (AD) and psoriasis with 100 percent accuracy using adhesive tape strips, a non-invasive alternative to skin biopsy. The research will be published online today in the Journal of Allergy and Clinical Immunology.

21 Jul 2020

GlobalData: Hematology tests can be a prognostic marker to predict severity of COVID-19 patients

With the rapid increase in the number of COVID-19 cases across India, identifying the critically ill COVID-19 patients in the early stage of infection can help in assessing the risk stratification and clinical management.

21 Jul 2020

Researchers identify underlying mechanism for metabolic memory and diabetic complications

For people with diabetes, vascular complications like kidney disease and atherosclerosis, which can lead to poor health and even death, are seen at increased rates.

20 Jul 2020

Current choline intake levels are too low for most Americans, say health and nutrition experts

On Wednesday, July 15, 2020, the Dietary Guidelines Advisory Committee (DGAC or Committee) - a group comprised of 20 nationally recognized health and nutrition experts - published the Scientific Report of the 2020 Dietary Guidelines Advisory Committee: Advisory Report to the Secretary of Agriculture and the Secretary of Health and Human Services.

20 Jul 2020

Biomarker News and Research

Further Reading

Simple blood test may be a great advance for people with and at risk for Alzheimer's

New multi-analyte blood test may open up new potentials in personalized medicine

Study identifies phosphorylation-based biomarkers to guide cancer therapy

OU physician receives $1.6 million NIH grant for knee osteoarthritis research

UArizona aims to develop a device for quick and accurate detection of pathogens, biological threats

Indiana University School of Medicine leads the first study of Diabetic Foot Consortium

First-ever multicenter network to study diabetic foot ulcers

Non-invasive urine test being offered free to the NHS to help clear bladder cancer diagnoses backlog

SphingoTec launches point-of-care test for bio-ADM, a biomarker for life threatening endothelial dysfunction

Epigenomic modifications play key role in the development of lung tumors

Ultivue and OracleBio partner to help advance personalized tumor characterization and clinical oncology research using multiplex immunofluorescence

C-Path gets positive response from FDA for drug-induced skeletal muscle injury safety biomarkers

SphingoTec introduces a CE-IVD-marked point-of-care test to determine blood levels of bio-ADM

Novel biomarkers for diagnosis of ureteropelvic junction obstruction in infants

Scientific evidence shows GLDH is a safe biomarker for drug-induced liver injury

Glycome shift in epidermal stem cells could serve as potential biomarker of aging

Newly identified gene biomarker can distinguish atopic dermatitis and psoriasis with excellent accuracy

GlobalData: Hematology tests can be a prognostic marker to predict severity of COVID-19 patients

Researchers identify underlying mechanism for metabolic memory and diabetic complications

Current choline intake levels are too low for most Americans, say health and nutrition experts

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