Clinical Trial News and Research

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Ingestible capsule can monitor vital signs from within the patient's GI tract

Diagnosing sleep disorders such as sleep apnea usually requires a patient to spend the night in a sleep lab, hooked up to a variety of sensors and monitors.

17 Nov 2023

Long-term monitoring of gene therapy patients crucial for safety, study says

Medical research has shown promising results regarding the potential of gene therapy to cure genetic conditions such as sickle cell disease and the findings of this study, published in Nature Medicine, offer important new insights into processes happening in the body after treatment.

16 Nov 2023

Landmark studies present new era for bladder cancer treatment

After 40 years of treating metastatic bladder cancer with chemotherapy as a primary treatment, scientists now present a new approach using immunotherapy combinations.

16 Nov 2023

Study reveals acupuncture and massage as effective pain management in advanced cancer

In a clinical trial, acupuncture and massage therapy significantly reduced pain, fatigue, and insomnia, enhancing quality of life in advanced cancer patients over 26 weeks.

16 Nov 2023

Fecal microbiota transplantation boosts survival in metastatic colorectal cancer treatment

A recent study in eClinicalMedicine found that fecal microbiota transplantation, combined with fruquintinib and tislelizumab, significantly improved survival rates in patients with microsatellite stable metastatic colorectal cancer, showing manageable safety and notable increases in progression-free and overall survival.

15 Nov 2023

Researchers discover genetic mechanism behind pancreatic cancer metastasis

Pancreatic cancer is tricky to manage because it spreads easily and early, and the tumors have a unique biological makeup.

15 Nov 2023

Scientists develop an improved method to study Parkinson's disease in the lab

A recent study published in Progress in Neurobiology and led by researchers at the University of Arizona College of Medicine – Tucson has developed an improved method to study Parkinson's disease in the lab.

15 Nov 2023

Experts question Pfizer's failure to inform pregnant women of safety signal in GSK RSV vaccine trial

A debate has broken out over whether Pfizer should have told pregnant women taking part in its maternal respiratory syncytial virus (RSV) vaccine trial that a trial of a similar GSK vaccine was stopped over a safety signal around preterm birth, an investigation by The BMJ can reveal.

15 Nov 2023

Autoimmune rheumatic disease patients benefit significantly from fourth COVID-19 vaccine dose

Patients with autoimmune rheumatic diseases, which include rheumatoid arthritis and other chronic disorders that cause inflammation, are at increased risk of SARS-CoV-2 infection, as well as death due to severe COVID-19.

15 Nov 2023

RNA-based molecular subtypes can help predict response to chemotherapy in muscle-invasive bladder cancer

RNA-based molecular subtypes modestly improved predictions for pathologic downstaging in muscle-invasive bladder cancer.

15 Nov 2023

Oral nicotine pouches fail to satisfy cravings of current smokers

Oral nicotine pouches, a tobacco-leaf-free product marketed as an alternative to cigarettes, do little to curb current smokers' nicotine cravings, according to a new study.

15 Nov 2023

Regenerative medicine takes leap forward with nasal cartilage-derived cartilage grafts

The Department of Biomedicine at the University of Basel and the University Hospital Basel, today announced that it delivered the first surgical procedure to treat Osteoarthritis (OA) in humans.

15 Nov 2023

Cannabis shows promise in easing endometriosis pain, new research suggests

The Journal of Clinical Medicine review explores cannabis as a self-management strategy for endometriosis pain, revealing its potential to reduce gut inflammation and improve gut permeability, thereby alleviating bloating and suppressing pain through interactions with the endocannabinoid system and gut microbiota.

14 Nov 2023

Delaying cord clamping could save lives of premature babies

Waiting for two minutes or longer to clamp the umbilical cord of a premature baby soon after birth could help reduce the risk of death, compared with immediately clamping the umbilical cord, or waiting a shorter time before doing so.

14 Nov 2023

Aspirin avoidance improves clinical outcomes in patients with advanced heart failure

Left ventricular assist devices (LVADs) are pumps that are used to circulate blood in patients with weakened hearts due to advanced heart failure. Mechanical stress on these implants can make patients susceptible to blood clots, and patients are required to take anti-clotting medications including vitamin-k antagonists (VKA) and aspirin.

14 Nov 2023

Vegan diet with soy significantly reduces hot flashes in postmenopausal women

A low-fat vegan diet that includes soy fosters changes in the gut microbiome that decrease postmenopausal vasomotor symptoms, or hot flashes, overall by 95%, according to a new study by the Physicians Committee for Responsible Medicine.

14 Nov 2023

Study provides insights into longevity of neutralizing antibodies in HIV-1 infection

An international team has for the first time researched the longevity of neutralizing antibodies in HIV-1-infected people.

14 Nov 2023

New app aims to ease burden on caregivers of dementia patients

With the number of Americans living with dementia expected to more than double to 13.8 million by 2060, two Regenstrief Institute research scientists and Indiana University professors have created an app to ease the burden on caregivers.

14 Nov 2023

IU researchers receive $5 million grant to improve care for adolescents with opioid use disorder

IU School of Medicine researchers are taking steps to improve the accessibility and quality of care for adolescents experiencing opioid use disorder (OUD) and other substance use disorders (SUDs), thanks to a new $5 million grant from the National Institute of Health's Helping to End Addiction Long-Term (HEAL) Initiative.

14 Nov 2023

Genetic test for antidepressants could save millions and improve patient outcomes

A special kind of genetic test that helps determine the best antidepressant for patients with moderate-to-severe depression could generate substantive health system savings and greatly improve patient outcomes, according to new research from the University of British Columbia.

14 Nov 2023

Clinical Trial News and Research

Ingestible capsule can monitor vital signs from within the patient's GI tract

Long-term monitoring of gene therapy patients crucial for safety, study says

Landmark studies present new era for bladder cancer treatment

Study reveals acupuncture and massage as effective pain management in advanced cancer

Fecal microbiota transplantation boosts survival in metastatic colorectal cancer treatment

Researchers discover genetic mechanism behind pancreatic cancer metastasis

Scientists develop an improved method to study Parkinson's disease in the lab

Experts question Pfizer's failure to inform pregnant women of safety signal in GSK RSV vaccine trial

Autoimmune rheumatic disease patients benefit significantly from fourth COVID-19 vaccine dose

RNA-based molecular subtypes can help predict response to chemotherapy in muscle-invasive bladder cancer

Oral nicotine pouches fail to satisfy cravings of current smokers

Regenerative medicine takes leap forward with nasal cartilage-derived cartilage grafts

Cannabis shows promise in easing endometriosis pain, new research suggests

Delaying cord clamping could save lives of premature babies

Aspirin avoidance improves clinical outcomes in patients with advanced heart failure

Vegan diet with soy significantly reduces hot flashes in postmenopausal women

Study provides insights into longevity of neutralizing antibodies in HIV-1 infection

New app aims to ease burden on caregivers of dementia patients

IU researchers receive $5 million grant to improve care for adolescents with opioid use disorder

Genetic test for antidepressants could save millions and improve patient outcomes

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