Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Genetic study helps identify obese diabetes patients who are at risk of developing NAFLD

A groundbreaking study of nearly 2,300 extremely obese diabetes patients, led by the Translational Genomics Research Institute, has identified genes associated with unhealthy liver function.

2 Oct 2013

NIH award strengthens pioneering work in cystic fibrosis at Dartmouth's School of Medicine

The National Institutes of Health (NIH) has awarded a $5.9 million grant to support an Institutional Development Award (IDeA) Lung Biology Center of Biomedical Research Excellence (COBRE) at the Geisel School of Medicine at Dartmouth.

1 Oct 2013

Scientists discover two new compounds that could help treat CF patients having common mutation

Cystic fibrosis is a lethal genetic disorder that in France affects one child per 4,500 births. An international team led by scientists at the Institut Fédératif de Recherche Necker-Enfants Malades (CNRS/Inserm/Université Paris Descartes), led by Aleksander Edelman, has recently discovered two new compounds that could be used to treat patients carrying the most common mutation.

30 Sep 2013

Scientists unravel secrets of mechanism that snips our genes

Certain diseases such as cystic fibrosis and muscular dystrophy are linked to genetic mutations that damage the important biological process of rearranging gene sequences in pre-messenger RNA, a procedure called RNA splicing.

27 Sep 2013

Scientists study genetic factors involved in complex diseases

Although heavily studied, the specific genetic causes of "complex diseases," a category of disorders which includes autism, diabetes and heart disease, are largely unknown due to byzantine genetic and environmental interactions.

27 Sep 2013

PneumRx performs over 1500 RePneu LVRC treatments for patients with severe emphysema

PneumRx, Inc., a leader in interventional pulmonology, announced that over 1500 procedures have been performed using the RePneu Lung Volume Reduction Coil System for patients with severe emphysema.

26 Sep 2013

Stem cell lines are ideal research tools for designing models to understand disease progression

Scientists from King's College London have announced that 16 human embryonic stem (hES) cell lines have been approved by the US National Institutes of Health (NIH) and placed on their Stem Cell Registry, making them freely available for federally-funded research in the USA.

25 Sep 2013

Simple traffic light test helps reduce drinking rates in people with risk of liver disease

A simple 'traffic light' test that detects hidden liver fibrosis and cirrhosis in high risk populations could reduce harmful drinking rates and potentially prevent hundreds of alcohol-related deaths a year.

25 Sep 2013

Abbvie, Galapagos Ink Up To $405M CF Collaboration

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24 Sep 2013

Karo Bio, 4D Science Team Up On Treatments For Fibrotic Diseases

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23 Sep 2013

MRE imaging technique accurately detects chronic liver disease in children

A new, non-invasive imaging technique, magnetic resonance elastography (MRE), can now help physicians accurately detect fibrosis (scarring) in children with chronic liver disease - a growing problem due in part to increasing obesity rates.

21 Sep 2013

IPF World Week underlines the need for integrated approach towards idiopathic pulmonary fibrosis

This year's IPF World Week (September 21-29) sees healthcare professionals, patient advocacy groups, people living with idiopathic pulmonary fibrosis (IPF), who have an estimated median survival time of two to five years, and their families calling for an integrated approach to further strengthen the national and international network of people working to support patients with this fatal orphan lung disease.

20 Sep 2013

Parenting stress among caregivers of children with chronic illness: A systematic review

The extra demands on parents of chronically ill children cause stress that affects the whole family, according to a systematic review conducted by Case Western Reserve University researchers that also explored what factors in the child's care most contribute to the added strain.

19 Sep 2013

VBP15 drug shows early promise for treatment of Duchenne muscular dystrophy

A preclinical study led by researchers at Children's National Medical Center has found that a new oral drug shows early promise for the treatment of Duchenne muscular dystrophy.

18 Sep 2013

Sigma-Tau Pharmasource, Aradigm Ink Manufacturing Deal For Respiratory Disease Treatment

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16 Sep 2013

Scientists discover promising potential drug target for cystic fibrosis

Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg and Regensburg University, both in Germany, and the University of Lisboa, in Portugal, have discovered a promising potential drug target for cystic fibrosis.

13 Sep 2013

New open access Journal of Clinical and Translational Endocrinology from Elsevier

Elsevier, a world-leading provider of scientific, technical and medical information products and services, is pleased to announce the launch of a new open access research publication - Journal of Clinical and Translational Endocrinology (JCTE).

12 Sep 2013

Biomarker analysis of Vectibix for mCRC published in New England Journal of Medicine

Amgen today announced the publication of a biomarker analysis of Vectibix (panitumumab) in combination with FOLFOX, a type of oxaliplatin-based chemotherapy, for the first-line treatment of patients with metastatic colorectal cancer.

12 Sep 2013

Improved lung function in patients with moderate asthma severity observed with investigational Tiotropium

Boehringer Ingelheim will present a pooled analysis of new data from the Phase 3 UniTinA-asthma® program at the European Respiratory Society (ERS) Annual Congress 2013 in Barcelona. The data from the individual MezzoTinA-asthma® Phase 3 studies (NCT01340209 and NCT00565266), from which the pooled data are derived, show the addition of tiotropium delivered via the Respimat® inhaler to medium-dose maintenance inhaled corticosteroid (ICS) therapy (defined as 400-800 µg budesonide/day or equivalent) improved lung function and provided sustained bronchodilation over 24 hours in patients with moderate asthma and airflow limitation. Tiotropium is being investigated to determine the medicine’s efficacy in treating asthma patients and is not currently approved for this indication.

11 Sep 2013

New advances toward making molecular prosthetics a reality

The vision for a new branch of medicine, inspired by the ancient field that began with peg legs and hand hooks, commanded the spotlight in a major address by its pioneer here today at the 246th National Meeting & Exposition of the American Chemical Society, the world’s largest scientific society.

11 Sep 2013

Fibrosis News and Research

Further Reading

Genetic study helps identify obese diabetes patients who are at risk of developing NAFLD

NIH award strengthens pioneering work in cystic fibrosis at Dartmouth's School of Medicine

Scientists discover two new compounds that could help treat CF patients having common mutation

Scientists unravel secrets of mechanism that snips our genes

Scientists study genetic factors involved in complex diseases

PneumRx performs over 1500 RePneu LVRC treatments for patients with severe emphysema

Stem cell lines are ideal research tools for designing models to understand disease progression

Simple traffic light test helps reduce drinking rates in people with risk of liver disease

Abbvie, Galapagos Ink Up To $405M CF Collaboration

Karo Bio, 4D Science Team Up On Treatments For Fibrotic Diseases

MRE imaging technique accurately detects chronic liver disease in children

IPF World Week underlines the need for integrated approach towards idiopathic pulmonary fibrosis

Parenting stress among caregivers of children with chronic illness: A systematic review

VBP15 drug shows early promise for treatment of Duchenne muscular dystrophy

Sigma-Tau Pharmasource, Aradigm Ink Manufacturing Deal For Respiratory Disease Treatment

Scientists discover promising potential drug target for cystic fibrosis

New open access Journal of Clinical and Translational Endocrinology from Elsevier

Biomarker analysis of Vectibix for mCRC published in New England Journal of Medicine

Improved lung function in patients with moderate asthma severity observed with investigational Tiotropium

New advances toward making molecular prosthetics a reality

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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