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Biosimilar drugs are cheaper than biologics. Are they similar enough to switch?

It took years for Elle Moxley to get a diagnosis that explained her crippling gastrointestinal pain, digestion problems, fatigue, and hot, red rashes.

23 Sep 2021

In-mouth production of volatile sulfur compounds causes children to dislike Brassica vegetables

Many children, as well as adults, dislike Brassica vegetables, such as broccoli, cauliflower, cabbage and Brussels sprouts.

22 Sep 2021

Gram-positive and -negative bacteria found to be involved in periodontal bone loss

Mouths are filthy, harboring the second largest microbiome of the human body. Some bacteria can help break down food, among other responsibilities; other bacteria can travel into the mouth on food, fingers, pen caps and more to contribute to gum disease and other oral infections.

22 Sep 2021

Doubling excise duties could prevent alcohol-attributable cancers

In a recent modeling study, scientists at Technische Universität Dresden have examined the impact of increasing taxes on alcoholic beverages on alcohol-attributable cancers in the World Health Organization (WHO) European Region.

22 Sep 2021

Novel anti-hormonal therapy may be a new treatment option for early-stage breast cancer

Early results from a UCLA-led clinical trial found treating women with estrogen receptor (ER)-positive and human epidermal growth factor receptor-2 (HER2)-negative early breast cancers with a novel type of anti-hormonal therapy, called an oral selective estrogen receptor degrader (SERD), led to clinically meaningful reductions in tumor activity prior to surgery.

21 Sep 2021

Higher white matter extracellular free-water related to cognitive dysfunction in lupus patients

Systemic lupus erythematosus (SLE) is an autoimmune disease in which the immune system attacks the body's own tissues, causing widespread inflammation and damage in the affected organs.

18 Sep 2021

Dentists chip away at uninsured problem by offering patients membership plans

Nevada dentist David White has seen diseased and rotted teeth in the mouths of patients who routinely put off checkups and avoided minor procedures such as fillings. While dental phobia is a factor, White said, the overriding reason people avoid treatment is cost.

17 Sep 2021

Long-term injectables plus counseling improve medication adherence in bipolar disorder patients

Researchers have found that adherence to taking medications improved in people with bipolar disorder with the use of long-term injectable meds combined with psychosocial intervention.

17 Sep 2021

UTSW researchers discover how vitamin A enters immune cells in the intestines

Immunologists and geneticists at UT Southwestern Medical Center have discovered how vitamin A enters immune cells in the intestines – findings that could offer insight to treat digestive diseases and perhaps help improve the efficacy of some vaccines.

16 Sep 2021

Live oral SARS-CoV-2 vaccine provides partial protection in Rhesus Macaques

A new study describes the partial protection against respiratory infection with SARS-CoV-2 following gut inoculation with a live attenuated virus.

16 Sep 2021

Rockefeller saliva test turns out to be easier and safer to administer than conventional COVID tests

In the early days of the pandemic, with commercial COVID tests in short supply, Rockefeller's Robert B. Darnell developed an in-house assay to identify positive cases within the Rockefeller community.

16 Sep 2021

Phase I trial investigates using antiparasitic nitazoxanide for treatment of COVID-19

In a recent study, researchers investigate the possibility of using the thiazolide antiparasitic nitazoxanide for the treatment of COVID-19.

15 Sep 2021

A sweet pill to swallow: oral nucleoside analog of Remdesivir improved SARS-CoV-2 pathogenesis in mice

A new study focused on in vitro antiviral activity in various cell models and in vivo therapeutic efficacy of oral GS-621763 in a mouse model of SARS-CoV-2 pathogenesis.

15 Sep 2021

Pregnancy complications with COVID-19

An important new article published in the Clinical Medicine Journal discusses pregnancy complicated with COVID-19.

14 Sep 2021

Gorillas at Atlanta Zoo have been infected by SARS-CoV-2

At Zoo Atlanta, 18 western lowland gorillas are currently receiving treatment for COVID-19 as initial and tests came back positive.

14 Sep 2021

Age-related differences in immune dynamics in rhesus macaques infected with SARS-CoV-2

In a recent study, authors explore the relationship between age and immune response to COVID-19.

13 Sep 2021

An oral COVID-19 vaccine induces mucosal and protective immunity

Researchers have collaborated to resolve the aforementioned problems associated with injection vaccines to create a thermostable vaccine that can be taken orally.

13 Sep 2021

Drugs that mimic effects of cigarette smoke could become a potential tool to fight COVID-19

Researchers have identified two drugs that mimic the effect of chemicals in cigarette smoke to bind to a receptor in mammalian cells that inhibits production of ACE2 proteins, a process that appears to reduce the ability of the SARS-CoV-2 virus to enter the cell.

12 Sep 2021

UGA research offers hope for a viable therapeutic to combat COVID-19

As COVID-19 cases continue to skyrocket across the U.S. and the world, few options are available for treating patients infected with the SARS-CoV-2.

11 Sep 2021

Restoring beneficial gut microbes to enhance the efficacy of cancer immunotherapy

The gut microbiome - the collection of bacteria, viruses, fungi, and other microorganisms that reside in our gastrointestinal tracts - can impact us in a variety of different ways, from our metabolism to our mood.

9 Sep 2021

Oral News and Research

Biosimilar drugs are cheaper than biologics. Are they similar enough to switch?

In-mouth production of volatile sulfur compounds causes children to dislike Brassica vegetables

Gram-positive and -negative bacteria found to be involved in periodontal bone loss

Doubling excise duties could prevent alcohol-attributable cancers

Novel anti-hormonal therapy may be a new treatment option for early-stage breast cancer

Higher white matter extracellular free-water related to cognitive dysfunction in lupus patients

Dentists chip away at uninsured problem by offering patients membership plans

Long-term injectables plus counseling improve medication adherence in bipolar disorder patients

UTSW researchers discover how vitamin A enters immune cells in the intestines

Live oral SARS-CoV-2 vaccine provides partial protection in Rhesus Macaques

Rockefeller saliva test turns out to be easier and safer to administer than conventional COVID tests

Phase I trial investigates using antiparasitic nitazoxanide for treatment of COVID-19

A sweet pill to swallow: oral nucleoside analog of Remdesivir improved SARS-CoV-2 pathogenesis in mice

Pregnancy complications with COVID-19

Gorillas at Atlanta Zoo have been infected by SARS-CoV-2

Age-related differences in immune dynamics in rhesus macaques infected with SARS-CoV-2

An oral COVID-19 vaccine induces mucosal and protective immunity

Drugs that mimic effects of cigarette smoke could become a potential tool to fight COVID-19

UGA research offers hope for a viable therapeutic to combat COVID-19

Restoring beneficial gut microbes to enhance the efficacy of cancer immunotherapy

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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