Transplant News and Research

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New treatment strategies increase lifespan of transplanted kidneys

New treatment strategies over the last few decades have meant that nowadays 95% of transplanted kidneys function well for at least one year and that the average lifespan of a transplanted organ is between 10 and 15 years.

29 May 2017

Diabetic donor kidneys may offer greater survival benefit to transplant candidates

A new study indicates that receiving donor kidneys from individuals with diabetes may offer a greater survival benefit than remaining on the waitlist for many transplant candidates.

27 May 2017

Experts outline new approach to total abdominal wall transplantation for complex cases

For some patients undergoing intestinal or multi-organ transplantation, closing the abdominal wall poses a difficult surgical challenge.

26 May 2017

New drug offers hope to patients with hepatitis C

Patients with hepatitis C who suffer from advanced stages of liver disease have renewed hope, thanks to findings by researchers who have discovered that a new drug significantly reduces their risk of death and need for transplantation.

26 May 2017

Diabetic donor kidneys could save lives of patients on transplant waitlist

There are more than 98,000 people currently awaiting a kidney transplant in the United States. But the organs are in short supply: only about 17,000 patients will receive transplants each year.

25 May 2017

U-M research reveals important clues about invasion of polyomaviruses

Every cell in our body runs like a tiny factory that makes specialized products, using the carefully guarded instructions kept in the CEO's office.

24 May 2017

Seattle Children’s opens first clinical trial to study IBD and GVHD in pediatric patients

In an effort to find new strategies to personalize treatment for pediatric patients, Seattle Children's has opened the first clinical trial applying next-generation T-cell receptor sequencing and single-cell gene expression analysis to better understand how the immune system drives both inflammatory bowel disease in pediatric autoimmunity patients and graft-versus host disease in pediatric bone marrow transplant patients.

From 10x Genomics, Inc. 23 May 2017

Study examines state-level factors contributing to variation in MVC-related pediatric mortality

Unintentional injury is the leading cause of pediatric death in the U.S. and motor vehicle crashes (MVCs) are the most common cause of injury.

23 May 2017

Researchers show how diesel fumes could potentially worsen underlying respiratory conditions

Scientists have shown how diesel fumes trigger respiratory reflexes which could potentially worsen underlying conditions, such as asthma.

22 May 2017

Study identifies two T cell biomarkers that may predict survival trajectory of IPF patients

Two T cell biomarkers appear to predict the survival trajectory of patients with idiopathic pulmonary fibrosis (IPF), a lung disease that has a varied, but ultimately devastating, impact on patients, according to new research presented at the ATS 2017 International Conference.

22 May 2017

Study: Angiotensin II can safely improve blood pressure among critically ill patients with hypotension

Sixty years after Cleveland Clinic researchers first isolated the role of angiotensin II in controlling blood pressure, a new international study led by Cleveland Clinic researchers shows that the compound can safely improve blood pressure among critically ill patients who are experiencing life-threatening hypotension, or low blood pressure.

22 May 2017

Researchers discover innovative way to produce hematopoietic stem cells

A study published on May 17 in Nature, discovers an innovative method to produce infinite supply of healthy blood cells from the readily available cells that line blood vessels. This achievement by the researchers at Weill Cornell Medicine marks the first time that any research group has generated such blood-forming stem cells.

18 May 2017

Researchers explore new treatment combination for pediatric patients with Hodgkin lymphoma

Pediatric and young adult patients whose Hodgkin lymphoma has recurred or is resistant to initial treatment can achieve remission and even cure with secondary treatments.

18 May 2017

Study highlights need to monitor transplant donor and recipient for identifying M. hominis infection

The way in which heart and lung transplant recipients acquired a specific species of bacteria, Mycoplasma hominis, had been previously undefined, and the bacterium was difficult to test.

16 May 2017

New IsoPSA assay detects prostate cancer more precisely than current tests

A team of researchers from Cleveland Clinic, Louis Stokes Cleveland VA Medical Center, Kaiser Permanente Northwest, and other clinical sites have demonstrated that a new blood test known as IsoPSA detects prostate cancer more precisely than current tests in two crucial measures - distinguishing cancer from benign conditions, and identifying patients with high-risk disease.

15 May 2017

Study finds no clear benefit of stem-cell transplant for double-hit lymphoma patients in remission

Patients with double hit lymphoma (DHL) who undergo autologous stem-cell transplantation (autoSCT) after achieving remission are not more likely to remain in remission or live longer than patients who do not undergo autoSCT, according to a new analysis from the Perelman School of Medicine and the Abramson Cancer Center of the University of Pennsylvania.

15 May 2017

Study provides insights into how HCMV infection causes birth defects

Fresh insights into how a common virus replicates could pave the way for new therapies to stop its spread.

15 May 2017

CUMC researchers create new organoids that mimic features of full-sized lung

New lung "organoids"-tiny 3-D structures that mimic features of a full-sized lung- have been created from human pluripotent stem cells by researchers at Columbia University Medical Center. The team used the organoids to generate models of human lung diseases in a lab dish, which could be used to advance our understanding of a variety of respiratory diseases.

11 May 2017

Cancer screening for transplant patients do not meet existing guidelines, new study finds

People who have received organ transplants are at higher risk of developing and dying of cancer than the general population. Yet their rates of cancer screening do not meet existing guidelines, a new study has found.

9 May 2017

Individuals who follow healthy lifestyle less likely to have colorectal cancer risk, survey finds

A Cleveland Clinic colon cancer risk assessment survey found that respondents who exercised more followed a healthy diet and did not smoke were less likely to have a personal history of colorectal cancer or colon polyps.

8 May 2017

Transplant News and Research

New treatment strategies increase lifespan of transplanted kidneys

Diabetic donor kidneys may offer greater survival benefit to transplant candidates

Experts outline new approach to total abdominal wall transplantation for complex cases

New drug offers hope to patients with hepatitis C

Diabetic donor kidneys could save lives of patients on transplant waitlist

U-M research reveals important clues about invasion of polyomaviruses

Seattle Children’s opens first clinical trial to study IBD and GVHD in pediatric patients

Study examines state-level factors contributing to variation in MVC-related pediatric mortality

Researchers show how diesel fumes could potentially worsen underlying respiratory conditions

Study identifies two T cell biomarkers that may predict survival trajectory of IPF patients

Study: Angiotensin II can safely improve blood pressure among critically ill patients with hypotension

Researchers discover innovative way to produce hematopoietic stem cells

Researchers explore new treatment combination for pediatric patients with Hodgkin lymphoma

Study highlights need to monitor transplant donor and recipient for identifying M. hominis infection

New IsoPSA assay detects prostate cancer more precisely than current tests

Study finds no clear benefit of stem-cell transplant for double-hit lymphoma patients in remission

Study provides insights into how HCMV infection causes birth defects

CUMC researchers create new organoids that mimic features of full-sized lung

Cancer screening for transplant patients do not meet existing guidelines, new study finds

Individuals who follow healthy lifestyle less likely to have colorectal cancer risk, survey finds

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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