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Cardiovascular deaths unrelated to COVID-19 increased during the pandemic, study finds

As the number of COVID-19 infections continues to rise nationwide, more than 360,000 Americans have already died from the potentially deadly viral infection.

13 Jan 2021

Bleeding disorder linked to poor clinical outcomes in COVID-19 patients

The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is the pathogen responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic. Approximately 20-55% of hospitalized COVID-19 patients are reported to have deranged hemostatic laboratory parameters, which suggests coagulopathy.

12 Jan 2021

Researchers discover a new approach to inhibit intrahepatic cholangiocarcinoma

Reprogramming the rich connective tissue microenvironment of a liver cancer known as intrahepatic cholangiocarcinoma (ICC) inhibits its progression and resistance to standard chemotherapy in animal models, researchers from Massachusetts General Hospital have found.

12 Jan 2021

Clinicians at leading cardiac center report burnout and high levels of distress

More than half the clinicians surveyed at the Peter Munk Cardiac Centre reported burnout and high levels of distress according to a series of studies published today in the Canadian Medical Association Journal Open.

12 Jan 2021

Endothelial tissue injury significantly contributes to ARDS in COVID-19 patients, finds study

A recent study conducted by scientists from the Yokohama City University, Japan, has revealed that elevated alveolar endothelial injury markers in coronavirus disease 2019 (COVID-19) patients with acute respiratory distress syndrome (ARDS) are the main causative factors for alveolar barrier disruption. In COVID-19 patients with ARDS, endothelial injury persists for a longer time than epithelial injury.

12 Jan 2021

Link between fever, diarrhea, severe COVID-19, and persistent anti-SARS-CoV-2 antibodies

A new preprint research paper appearing on the medRxiv server describes a link between the persistence of neutralizing antibodies against the virus, disease severity, and specific COVID-19 symptoms.

7 Jan 2021

Potential role of chitinase 3-like-1 in severity of COVID-19

Now, an intriguing preprint research paper on the bioRxiv server reports the identification of an enzyme called chitinase 3-like-1 (CHI3L1) that mediates this age-dependent impact of the virus and could serve as a powerful therapeutic approach in mitigating the severity of COVID-19 in this high-risk group.

7 Jan 2021

Statins may protect the heart from damaging side-effects of early breast cancer treatment

New research from UHN's Peter Munk Cardiac Centre (PMCC) shows statins, commonly prescribed to lower cholesterol and reduce the risk of heart disease and stroke, may also protect the heart from damaging side-effects of early breast cancer treatment.

6 Jan 2021

Inhibition of blood clotting factor reduces the formation of brain metastases in mice

Brain metastases can only develop if cancer cells first exit the fine blood vessels and enter into the brain tissue.

5 Jan 2021

Six clearly distinguishable subtypes of prediabetes identified

All prediabetes is not the same: in people in the preliminary stages of type 2 diabetes, there are six clearly distinguishable subtypes, which differ in the development of the disease, diabetes risk, and the development of secondary diseases.

4 Jan 2021

Smoking traditional cigarettes along with e-cigarettes causes harmful health effects

Smoking traditional cigarettes in addition to using e-cigarettes results in harmful health effects similar to smoking cigarettes exclusively, according to new research published today in the American Heart Association's flagship journal Circulation.

4 Jan 2021

First human clinical trial validates the practicality, accuracy of oxygen-sensing liquid bandage

In the first human clinical trial, researchers at Massachusetts General Hospital and surgeons at Beth Israel Deaconess Medical Center have validated the practicality and accuracy of an oxygen-sensing liquid bandage that measures the concentration of oxygen in transplanted tissue

22 Dec 2020

Clinical psychologist evaluates the dangers of race-based norms in cognitive testing

A UCSF clinical psychologist has taken aim at the National Football League (NFL) for "race norming" black players diagnosed with dementia, a practice that is depriving them of the monetary awards allocated to former footballers with neurodegenerative disorders.

22 Dec 2020

Virtual telehealth platform enables kidney transplant evaluation from home

A virtual telehealth platform is allowing the surgery program at the Medical University of South Carolina to evaluate and wait-list patients for kidney transplantation despite reductions in direct, in-person health care visits brought about by the Coronavirus Disease 2019 (COVID-19) pandemic.

21 Dec 2020

Prior use of renin-angiotensin system inhibitors linked to reduced risk of death in older COVID-19 patients with hypertension

A new study, appearing as a preprint on the medRxiv* server, demonstrates the protective effect of drugs in older COVID-19 patients with hypertension.

21 Dec 2020

Detecting SARS-CoV-2 sequences in blood monocytes

A meeting with doctors from Wuhan presented a compelling observation to Professor Laura Manuelidis, MD, from the Yale Medical School early in 2020.

21 Dec 2020

Researchers are developing new criteria for clinical research of antiphospholipid syndrome

An international team of more than 80 collaborators led by Hospital for Special Surgery (HSS) investigators is developing new classification criteria for clinical research of antiphospholipid syndrome (APS), a life-threatening autoimmune clotting disorder.

17 Dec 2020

Vascular News and Research

Cardiovascular deaths unrelated to COVID-19 increased during the pandemic, study finds

Bleeding disorder linked to poor clinical outcomes in COVID-19 patients

Researchers discover a new approach to inhibit intrahepatic cholangiocarcinoma

Clinicians at leading cardiac center report burnout and high levels of distress

Endothelial tissue injury significantly contributes to ARDS in COVID-19 patients, finds study

Link between fever, diarrhea, severe COVID-19, and persistent anti-SARS-CoV-2 antibodies

Potential role of chitinase 3-like-1 in severity of COVID-19

Statins may protect the heart from damaging side-effects of early breast cancer treatment

Inhibition of blood clotting factor reduces the formation of brain metastases in mice

Six clearly distinguishable subtypes of prediabetes identified

Smoking traditional cigarettes along with e-cigarettes causes harmful health effects

First human clinical trial validates the practicality, accuracy of oxygen-sensing liquid bandage

Clinical psychologist evaluates the dangers of race-based norms in cognitive testing

Virtual telehealth platform enables kidney transplant evaluation from home

Prior use of renin-angiotensin system inhibitors linked to reduced risk of death in older COVID-19 patients with hypertension

Detecting SARS-CoV-2 sequences in blood monocytes

Researchers are developing new criteria for clinical research of antiphospholipid syndrome

Fish oil supplements not associated with increases in bad cholesterol

Study shows high prevalence of back pain in patients undergoing neuroendovascular procedures

Impaired blood vessel and kidney function underlie heart disease risk in people with HIV

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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